Navigation Links
Recent Genetic Discoveries Don't Improve Prediction of Breast Cancer
Date:7/11/2008

When added to risk assessment tool, SNPs made no difference, study finds

FRIDAY, July 11 (HealthDay News) -- The accuracy of predicting one's chances of developing breast cancer do not seem to improve even with the recent findings of some genetic markers for the disease, a new report says.

Scientists have identified seven single nucleotide polymorphisms (SNPs) that indicate a small but statistically significant increase in the risk of developing breast cancer. But when applied to existing models that use clinical factors, such as age and family history, to predict an individual's risk, they do not appear to change the prediction, according to a study in the July 8 online issue of the Journal of the National Cancer Institute.

Someone who is at high risk for breast cancer may choose to pursue more aggressive preventive strategies than a person at low risk, who may suffer side effects that far outweigh the benefits.

In the current study, Dr. Mitchell Gail of the National Cancer Institute found that adding the seven SNPs to the Breast Cancer Risk Assessment Tool (BCRAT) makes no improvement in the prediction accuracy. The BCRAT uses a woman's age, age at first menstruation and at birth of first child, family history of breast cancer, and breast biopsy results to predict her risk of disease to obtain its prediction.

"Experience to date and quantitative arguments indicate that a huge increase in the numbers of case patients with breast cancer and control subjects would be required in genome-wide association studies to find enough SNPs to achieve high discriminatory accuracy," Gail said in a prepared statement.

More information

The American Cancer Society has more about the risks of developing breast cancer.



-- Kevin McKeever


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Eat Seafood, See Weight Loss: Recent Study Finds Another Reason to Eat Seafood for a Fit Lifestyle
2. Health Insurance Premiums Rise 6.1 Percent in 2007, Less Rapidly Than in Recent Years But Still Faster Than Wages and Inflation
3. SearchMedica Finds Most Relevant and Now Most Recent Search Results
4. Lacey Veterinarian Awarded 2007 WSVMA Recent Graduate Award
5. Dr. Stephen Paget, Physician-in-Chief and Chairman, Division of Rheumatology, at Hospital for Special Surgery is Available to Comment on a Recent CDC Study on the Impact of Arthritis in the Work Place
6. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
7. Alcohol and cancer -- recent research and prevention opportunities
8. BioReliance Appoints Executive Chairman to be Interim CEO and Announces Recent Senior Executive Additions
9. Studies attribute recent increase in multiple myeloma survival to novel therapies
10. Congress Proclaims Support for Long Term Care Awareness Week; Recent Poll Shows Voters Want Long Term Care Included in Presidential Candidates Healthcare Proposals
11. Cell Therapeutics, Inc. (CTI) Reports Recent Accomplishments and Third Quarter 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Recent Genetic Discoveries Don't Improve Prediction of Breast Cancer
(Date:3/26/2015)... March 26, 2015 Visiting Nurse ... their 18th annual gala fundraiser, Lighting the Way, Brightening ... p.m. at The Madison Hotel in Morristown, NJ. ... entertainment by renowned musician Rio Clemente, delightful cuisine, an ... and Dave Hertzel. Additionally, two prestigious awards will be ...
(Date:3/26/2015)... 26, 2015 The Life Support ... to Hyperbaric Medicine” course, which is accredited by ... and the National Board of Diving & Hyperbaric ... course 4 times a year at several of ... tri-state region; registration is available on-line at: ...
(Date:3/26/2015)... On March 5, 2015, Portland Trail ... for the season with a torn Achilles tendon in ... Blazers were competing against Dallas, and was confirmed via ... Silva, M.D., who has treated many professional athletes, voiced ... could be prevented. , "Part of the problem ...
(Date:3/26/2015)... Volunteers will collectively walk hundreds of ... and funds to support the American Parkinson Disease ... Find the Cure. The Optimism Walk campaign ... more than 20 locations including, Boston, Chicago, Connecticut, Madison, ... Minnesota, Seattle, St. Louis, New York, Nevada, South Florida, ...
(Date:3/26/2015)... CT (PRWEB) March 26, 2015 CRN ... State Capitol Building to help celebrate the achievement of ... groundbreaking employment program serving some 500 people. , The ... The WorkPlace in partnership with the Connecticut ... and prepare long-term unemployed workers and place them at ...
Breaking Medicine News(10 mins):Health News:Morristown VNA Fundraiser to Honor Distinguished Community Members 2Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 2Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 3Health News:The Life Support Technologies Group (LST) Conducted its 30th Accredited “Introduction to Hyperbaric Medicine” Course for Health Care Professionals 4Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 2Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 3Health News:Sports Medicine Specialist Weighs In on Wesley Matthew’s Significant Tendon Injury; Can it be Prevented? 4Health News:American Parkinson Disease Association 2015 Optimism Walk Season Launches Nationwide 2Health News:CRN International Shows Support For Groundbreaking Connecticut Program To Aid The Unemployed 2
... 29 (HealthDay News) -- Not turning the clocks back an ... improve people,s health and well-being, according to an English expert. ... of "accessible" daylight hours during the fall and winter and ... senior fellow emeritus at the Policy Studies Institute in London. ...
... 29 (HealthDay News) -- More than half of the ... want to have full control over life-support choices and ... a new study. It included 230 surrogate decision ... who had about a 50 percent chance of dying ...
... THURSDAY, Oct. 28 (HealthDay News) -- Elderly kidney failure patients in ... transplant as they were in the mid-1990s, although the likelihood is ... in the United States have kidney failure, and 48 percent of ... upcoming issue of the Clinical Journal of the American Society ...
... Weill Cornell Medical College have identified a potential new treatment ... viruses for which there is currently no treatment or vaccine ... measles, mumps and the flu. The new research appears in ... Science (PLoS) Pathogens . The Nipah and Hendra viruses are ...
... Steven Reinberg HealthDay Reporter , THURSDAY, Oct. 28 ... pre-cancerous polyps and colon tumors appears to be more accurate ... test, Mayo clinic researchers say. The search for a highly ... sigmoidoscopy is a "Holy Grail" of colon cancer research. ...
... long life, but may do so at the expense of ... 11-year study of a population of wild sheep located on ... the animals, susceptibility to infection may give new insight into ... the same illness. The answer to this medical puzzle ...
Cached Medicine News:Health News:Is It Time to Ditch the Daylight Saving Time Switch? 2Health News:Most Health Proxies Would Make End-of-Life Decisions Themselves: Study 2Health News:Potential new treatment for deadly nipah and hendra viruses identified by Weill Cornell researchers 2Health News:Noninvasive Test for Colon Cancer Shows Promise in Early Trial 2Health News:Noninvasive Test for Colon Cancer Shows Promise in Early Trial 3Health News:Noninvasive Test for Colon Cancer Shows Promise in Early Trial 4Health News:Wild Scottish sheep could help explain differences in immunity 2Health News:Wild Scottish sheep could help explain differences in immunity 3
(Date:3/26/2015)... , March 26, 2015  The inaugural ... the use of health technology innovations that improve ... foster collaborations to improve development and adoption of ... the structures and processes within delivery systems that ... providers, investors, entrepreneurs, developers and other stakeholders, takes ...
(Date:3/26/2015)... , March 26, 2015 ... "Pharmacovigilance and Drug Safety Software Market by Functionality (Adverse ... On-demand/Cloud based (SAAS)), End-user (Pharma & Biotech Companies, ... by MarketsandMarkets, the Pharmacovigilance and Drug Safety Software ... of 6.5% during 2014-2019, and is expected to ...
(Date:3/26/2015)... -- Flexpoint Sensor Systems, Inc. (OTCBB: FLXT) today announced several ... shipped during the last 90 days. Flexpoint ... sensors for gloves and medical uses. Several new customers ... built for them. Some of these new clients include ... rehab; a major international electronics manufacturer who is using ...
Breaking Medicine Technology:HX360 To Highlight New, Innovative Technology-Based Solutions To Improve Care Coordination, Workflow, Patient Experience 2HX360 To Highlight New, Innovative Technology-Based Solutions To Improve Care Coordination, Workflow, Patient Experience 3HX360 To Highlight New, Innovative Technology-Based Solutions To Improve Care Coordination, Workflow, Patient Experience 4Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 2Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 3Pharmacovigilance and Drug Safety Software Market Worth $154.1 Million by 2019 4Flexpoint Sensor Systems, Inc. Expands Customer Base with New Orders of Sensors 2
Hard protective shields for post-operative or post-injury use. Universal, or Left/Right specific. Packaged 12 per box....
Hard protective shields for post-operative or post-injury use. Universal, or Left/Right specific. Packaged 12 per box....
Hard protective shields for post-operative or post-injury use. Universal, or Left/Right specific. Packaged 12 per box....
... precise episcleral, intrascleral, and intraocular hemostasis ... Rf diathermy delivers targeted coagulation with ... Eraser instruments, forceps and cables. This ... a high level of Wet-Field safety ...
Medicine Products: