Patient enrollment for the CAPTURE 2 trial is ongoing. The EXACT trial is closed and 30-day follow up has been completed.
About Stroke
Approximately 25 percent of strokes are caused by carotid artery disease. In carotid artery disease, arteries located on either side of the neck that supply blood to the brain become narrowed or blocked due to the deposition of fatty plaques that can lead to stroke. Stroke is the third leading cause of death in the United States and the number one cause of disability in adults, according to the American Heart Association. More than 700,000 Americans will have new (500,000) or recurrent (200,000) strokes each year, and more than 150,000 will die from the events.
About Carotid Artery Stenting
Carotid artery stenting is a minimally invasive alternative treatment
to surgery in which a stent is inserted into carotid arteries in the neck
in order to stabilize fatty plaque deposits and re-establish adequate blood
flow to the brain. Carotid stenting is usually accompanied by an embolic
protection filter designed to capture and remove any debris that becomes
dislodged during a carotid stenting procedure. Currently, carotid artery
stenting in the United States is approved by the FDA for treating patients
who are at high risk for experiencing adverse events from surgery or
carotid endarterectomy -- an invasive procedure in which the artery is
surgically opened and the plaque is removed. Abbott's carotid stenting
devices are also being investigated in a broader group of patients who are
not at high risk from surgery in two randomized clinical trials called
CREST and ACT I, which are comparing stentin
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