Navigation Links
Reach2HD, a Phase II study in Huntington's disease, launched
Date:6/7/2012

The Huntington Study Group (HSG), under the leadership of Ray Dorsey, M.D. with Johns Hopkins Medical and Diana Rosas, M.D. with Massachusetts General Hospital, is conducting a clinical trial in Huntington's disease (HD) throughout the United States and Australia, "A randomized, double-blind, placebo-controlled, study to assess the safety and tolerability, and efficacy of PBT2 in patients with early to mid-stage Huntington's disease" comparing a 100 mg dose or 250 mg dose versus placebo. The HSG is a not-for-profit group of physicians and other clinical researchers who are experienced in the care of HD patients and dedicated to clinical research of the disease. This trial is sponsored by Prana Biotechnology Limited (Melbourne, Australia) and is being managed by the University of Rochester Medical Center.

Huntington's disease is an inherited neurodegenerative disease which affects over 30,000 people in both the United States and Australia. HD is characterized by brain cell death that usually begins between the ages of 30 to 50, and results in motor, cognitive and behavioral signs and symptoms. While there are medications to help relieve some of the disease symptoms, there is no known treatment to address the cognitive impairment associated with HD.

Research has shown that normally occurring metals in the brain play a significant role in diseases such as Alzheimer's disease and more recently, HD. Researchers at Prana Biotechnology are identifying drugs designed to interrupt interactions between these biological metals and target proteins in the brain, to prevent deterioration of brain cells. One of the chemical compounds, called PBT2, has shown in animal models, and as well as in a small group of patients with Alzheimer's disease, that it may improve cognition. There is some indication in animal models of HD, that the drug may improve motor function and control, increase life span and reduce the amount of brain cell degeneration. Based on the
'/>"/>

Contact: Mark Michaud
mark_michaud@urmc.rochester.edu
585-273-4790
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ALS patients differ on treatment choices in later phases of disease
2. Study Suggests Vaccine May Help Kids With Brain Cancer
3. Study reveals how cancer drug causes diabetic-like state
4. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
5. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
6. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
7. No Added Cancer Risk From Hip Replacement Materials: Study
8. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
9. Early Study Finds Some Promise for Lung Cancer Vaccine
10. Narcissists Often Ace Job Interviews, Study Finds
11. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... (FQHCs) granted new patient appointments to Medicaid beneficiaries ... primary care practices (non-FQHCs), in addition to charging ... new 10-state University of Pennsylvania study published this ... data from a previous "secret shopper" study conducted ... FQHCs community health clinics that receive federal ...
(Date:9/30/2014)... research team has been awarded a three-year $1.7 ... (NIH) to develop new imaging technologies and data ... how large networks of neurons in the brain ... help researchers identify the precise interactions between millions ... and speaking, and alterations in these interactions that ...
(Date:9/30/2014)... Fat Burning Kitchen , the latest diet guide ... that is helping people learn the truth about so-called health ... in less than 24 hours has caught the attention of ... culture that is becoming so obsessed with diets and weight ... fact and fiction when it comes to health foods, eating ...
(Date:9/30/2014)... CA (PRWEB) September 30, 2014 ... providers in Turkey has gone up more than 79 ... The medical tourism company also reported total revenue tripled ... 2012. , The company’s professional strategy has allowed them ... — ultimately designed for patient comfort and privacy — ...
(Date:9/30/2014)... September 30, 2014 With the ... strains emerging every day, it’s a perfect time ... The EnviroShield system is an electro-static disinfectant delivery ... to surface normally missed with spray-on disinfectant applicators. ... that adds an electrostatic negative charge to the ...
Breaking Medicine News(10 mins):Health News:Medicaid and Uninsured patients obtain new patient appointments most easily at FQHCs 2Health News:UMD receives inaugural BRAIN Initiative Award 2Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 2Health News:Fat Burning Kitchen: Review Exposes Mike Geary’s 24-Hour Diet Transformation for Helping the Body Burn Fat Through a Natural Diet 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 4Health News:Columbus Janitorial Company Announces New Disinfecting System for your workplace 2
... delivers,winning practices for improving an organization,s operations - from ... in the Best,Practice Database, an online research repository managed ... review sample key findings and key metrics in these ... study at this address:, http://www3.best-in-class.com/dr287.htm , The Database ...
... are counting,down the days leading up to the holidays, ... of America reminds you that time is running out,to ... flexible spending,account., Made available through employers, flexible spending ... for out-of-pocket health expenses,such as an eye exam or ...
... Star will appear at Mattel Children,s Hospital UCLA,interacting with ... via ... Vapps, HighSpeedConferencing.com, NEW YORK, Dec. 12 ... technology and services worldwide, today,will premiere their inaugural "Vapps, ...
... to improve the sleep quality and comfort levels of ... according to research published today in the journal JAMA. ... the new drug dexmedetomidine with the commonly used sedative ... experienced by mechanically ventilated ICU patients and which help ...
... generator of beliefs about the world. The capacity of our ... force for controlling both behavior and emotion, but the basis ... , In the January issue of Annals ... in the lab of Mark Cohen, a professor of psychiatry ...
... December 12, 2007 Elsevier, a leading publisher ... announced that 45 French-language medical journals from Elsevier ... 3, 2008. , The titles, including Feuillets de ... represent a wide range of high-quality journals and ...
Cached Medicine News:Health News:Best Practice Database Adds New Research on Contract Management and New Product Development 2Health News:Ashlee Simpson to Read Holiday Stories to Children in Hospitals Throughout the Country Premiering 'Vapps' Holiday Storybook' Event 2Health News:Intensive care quality of sleep improved by new drug, reports study 2Health News:UCLA study shows different areas of the brain respond to belief, disbelief and uncertainty 2Health News:UCLA study shows different areas of the brain respond to belief, disbelief and uncertainty 3Health News:ScienceDirect to host French-language journals from Elsevier Masson 2
(Date:9/30/2014)... , Sept. 30, 2014  Decision Resources Group finds that the ... Australia , China , India ... at a strong rate through 2023. Dental implant procedure volumes will ... patient awareness rises. Other key findings from Decision Resources ... implant market: , Dental implant penetration: Penetration of ...
(Date:9/30/2014)... LOS ANGELES , Sept. 30, 2014   ... apnea shopping destination , today announced that it now ... ResMed . AirSense CPAPs are the first sleep apnea ... makes it simple and easy to track and share ... the overall effectiveness of their CPAP therapy.  In addition, ...
(Date:9/30/2014)... BRUNSWICK, N.J., Sept. 30, 2014 The ... Kessler Foundation and New Jersey Health Foundation (NJHF) ... and patient care programs has been announced by ... officer of Kessler Foundation and James M. ... "The experience of New Jersey Health ...
Breaking Medicine Technology:Asia Pacific Dental Implant Market Will Grow at a Strong Rate Through 2023 2Asia Pacific Dental Implant Market Will Grow at a Strong Rate Through 2023 3Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 2Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 3Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 4Kessler Foundation Partners with New Jersey Health Foundation To Start Innovative Companies To Change the Lives of People with Disabilities 2
... 8, 2011 PermaDerm™, an engineered skin substitute which ... prepared from a patient,s own skin cells, has been ... that the U.S. Department of Defense awarded more than ... of the therapeutic candidate for the treatment of severe ...
... a Carmel-headquartered software development and solutions firm has been ... 500 and mid-market businesses throughout the world since 1983. ... its extensive supply chain experience to develop supply chain ... Blue Horseshoe Intellectual Property (BHIP). Led ...
Cached Medicine Technology:PermaDerm™ Receives National Media Coverage 2Software Development Firm's New Intellectual Property Group, Blue Horseshoe IP Creates Solutions to Help Customers Optimize Supply Chain 2Software Development Firm's New Intellectual Property Group, Blue Horseshoe IP Creates Solutions to Help Customers Optimize Supply Chain 3
Curved left, Hardy Curettes, bayonet, working distance 120 mm, total length 241 mm....
Toothed pituitary rongeur. Straight....
Micro cup pituitary forceps, semi-malleable shafts....
Teardrop dissector. 90, 5 mm....
Medicine Products: