Navigation Links
Re-Routing Spinal Cord Signals Restores Movement in Paralyzed Rats
Date:5/31/2012

By Maureen Salamon
HealthDay Reporter

THURSDAY, May 31 (HealthDay News) -- In research that hints at new ways to tackle paralysis, a combination of drugs, electrical stimulation and "willpower-based training" prompted paralyzed rats to walk and even run.

But experts noted the treatment might not necessarily work in humans.

Researchers at the Swiss Federal Institute of Technology re-routed signals from the rats' brains to their spinal cords with chemical injections, electrodes and a chocolate reward that motivated them to walk voluntarily, supporting their entire weight on their hind legs.

"We expected that the rats would recover some degree of locomotor functions. We were, however, surprised about the extent of the recovery -- paralyzed rats were able to pass obstacles and run up stairs -- and the consistency with which we observed it," said study co-author Janine Heutschi, a doctoral student at the institute.

"Because the rats actively participate in the tasks, as opposed to automated movements, the brain is actively involved and is challenged to find new ways of controlling the hind limbs," she added. "Over time, new nerve connections are then formed."

The study findings are published in the June 1 issue of the journal Science.

About half of human spinal cord injuries lead to paralysis, which can be complete or partial. While the brain and spinal cord can often adapt and recover from moderate injury through a quality known as neuroplasticity, severe injuries can preclude recovery, the study authors noted.

In the new research, begun five years ago at the University of Zurich in Switzerland, rats with severed spinal cords were injected with chemicals known as monoamine agonists that replace the neurotransmitters dopamine, adrenaline and serotonin, which are released from the brains of healthy individuals to help coordinate lower body movement. About 10 minutes later, the
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Severely Obese Have More Complications With Spinal Surgery
2. Spinal cord injury researchers win Apple Award for article on niacin for dyslipidemia
3. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
4. High doses of load slows loss of bone in spinal cord injury
5. Spinal Manipulation, Home Exercise May Ease Neck Pain
6. Changes seen in cerebrospinal fluid levels before onset of Alzheimer dementia
7. Changes in Cerebrospinal Fluid May Signal Early Alzheimers
8. JSCM publishes revised International Standards for Neurological Classification of Spinal Cord Injury
9. Cleveland researchers find possible breakthrough to relieve pain following spinal cord injury
10. Spinal bleeding with brain injury may suggest abuse in young children
11. BMC selected spinal cord injury model system site by NIDRR
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Re-Routing Spinal Cord Signals Restores Movement in Paralyzed Rats
(Date:6/2/2015)... (PRWEB) June 02, 2015 Each year, ... Insiders’ Choice Beauty Awards. This year, the organization’s members ... the winner of the QVC® Beauty Quest Award at ... results-driven Micro Emulsion (ME) Technology and 2-in-1 approach to ... Also noting the brand’s loyal consumer and professional fan ...
(Date:6/2/2015)... 2015 SB 277 (CA Legislature, bit.ly/1Q0P8OY) ... to attend public or private school. SB277 cleared three ... the Appropriations Committee (Sacramento Bee, May 11, 2015, bit.ly/1Gh9jU7). ... , “We believe that this bill affects the ... than it will (the) affect public health of California.. ...
(Date:6/1/2015)... NY (PRWEB) June 02, 2015 ... Miriam Wirski as a 2015-2016 inductee into ... recognized with this prestigious distinction for leadership in business. ... professional women, boasting more than 700,000 members and over ... Miriam with this prestigious honor,” said NAPW President Star ...
(Date:6/1/2015)... June 02, 2015 The National ... Willey as a 2015-2016 inductee into its VIP ... with this prestigious distinction for leadership in safety, environment, ... networking organization exclusively for professional women, boasting more than ... "I’m pleased to present Lourinda with this important honor,” ...
(Date:6/1/2015)... The National Association of Professional Women ... (C), First Sergeant A Co., 15BSB , as a ... Circle. She is recognized with this prestigious distinction for ... networking organization exclusively for professional women, boasting more than ... “I'm pleased to recognize Sergeant Cornett with this important ...
Breaking Medicine News(10 mins):Health News:Scalisi Skincare Wins Coveted CEW QVC Beauty Quest Award for Innovative and Patented Formulation 2Health News:A Voice For Choice Releases A Statement As SB277 Is Referred To Single Assembly Committee And Bypasses Education and Judicial Scrutiny 2Health News:National Association of Professional Women Inducts Miriam Wirski, Holistic Life Coach, Into its VIP Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Lourinda Willey, Owner and Principal of Lourinda R. Willey LLC, Into its VIP Professional Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Lenita F. Cornett, First Sergeant of the US Military, Into its VIP Professional Woman of the Year Circle 2
... RIVERSIDE, California and NUREMBERG, Germany, June ... United States Food and Drug,Administration (FDA) has given 510k ... the Ziehm Vision(R) RFD, for marketing and,sales within the ... and interventional radiology, the Ziehm Vision RFD,mobile C-arm combines ...
... M.A.Z.E. ... is dedicated to helping parents save money and the giveaway is another chance for parents ... ... education with M.A.Z.E. Cord Blood Laboratories. M.A.Z.E. is offering a drawing to win a ...
... LONDON, June 10 ThirdForce, the UK,s leading,e-learning ... one of,the most respected care home companies in the UK, ... for Life,e-learning to enhance Barchester,s quality provision of care and ... a key component to the success of the,Barchester business; a ...
... percent of the 5.5 billion kilograms of toxic pollutant ... can be traced to just 30 substances from 15 ... according to the latest tri-national pollution report from the ... 2005, released today,represents the most complete picture of pollution ...
... difference to Ontario,s community mental health system? According to ... the answer is yes. Ontarians now have access to ... also highlights the system,s limited resources to serve all ... for Addiction and Mental Health (CAMH),s Dr. Paula Goering, ...
... New Tissue Dissection System Used by Italian Surgeons in Oncology ... PALO ALTO, Calif., June 10 PEAK Surgical, Inc., today ... surgeons in the European Union, where the innovative tissue dissection ... , Dr. Raul Pellini and Prof. Giuseppe Spriano, ear, nose ...
Cached Medicine News:Health News:SVS 2009: Ziehm Imaging Sets a New Standard in Mobile Imaging With the Ziehm Vision RFD 2Health News:SVS 2009: Ziehm Imaging Sets a New Standard in Mobile Imaging With the Ziehm Vision RFD 3Health News:M.A.Z.E. Cord Blood Laboratories Offers Expectant Parents The Chance To Win A $500 Savings Bond 2Health News:Barchester Healthcare Gains Skills for Life With ThirdForce 2Health News:Barchester Healthcare Gains Skills for Life With ThirdForce 3Health News:Latest trinational report presents most complete picture of North American industrial pollution 2Health News:Latest trinational report presents most complete picture of North American industrial pollution 3Health News:Evaluation shows $167 million investment improves community mental health system, but many still in need 2Health News:PEAK Surgical Announces First Use of PEAK PlasmaBlade(TM) in Europe 2Health News:PEAK Surgical Announces First Use of PEAK PlasmaBlade(TM) in Europe 3Health News:PEAK Surgical Announces First Use of PEAK PlasmaBlade(TM) in Europe 4
(Date:6/2/2015)... MADRID , June 2, 2015 /PRNewswire/ ...   10503), vorgestellt auf dem Jahrestreffen der ... PharmaMar teilt mit, dass Janssen Research ... multizentrischen Phase-3-Studie SAR3007 bekannt gegeben hat, ... (progression-free survival, PFS) mit Trabectedin (YONDELIS ® ...
(Date:6/1/2015)... 2, 2015 Amgen (NASDAQ: AMGN ... a Phase 1b study to evaluate the safety ... immunotherapy, in combination with Roche,s investigational anti-PDL1 therapy, ... triple-negative breast cancer and colorectal cancer with liver ... oncolytic immunotherapy designed to selectively replicate in tumors ...
(Date:6/1/2015)... June 1, 2015 /PRNewswire/ - Pivotal Therapeutics Inc. ... with a focus on Omega-3 therapies for cardiovascular ... highlights and financial results for the three months ... herein are in Canadian dollars unless otherwise stated. ... business strategies despite its limited financial resources," stated ...
Breaking Medicine Technology:PharmaMar gibt bekannt, Janssens Studie zeige, dass Trabectedin die Krankheitsbekämpfung bei Patienten mit fortgeschrittenem Weichgewebesarkom verbessert 2PharmaMar gibt bekannt, Janssens Studie zeige, dass Trabectedin die Krankheitsbekämpfung bei Patienten mit fortgeschrittenem Weichgewebesarkom verbessert 3PharmaMar gibt bekannt, Janssens Studie zeige, dass Trabectedin die Krankheitsbekämpfung bei Patienten mit fortgeschrittenem Weichgewebesarkom verbessert 4PharmaMar gibt bekannt, Janssens Studie zeige, dass Trabectedin die Krankheitsbekämpfung bei Patienten mit fortgeschrittenem Weichgewebesarkom verbessert 5PharmaMar gibt bekannt, Janssens Studie zeige, dass Trabectedin die Krankheitsbekämpfung bei Patienten mit fortgeschrittenem Weichgewebesarkom verbessert 6Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 2Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 3Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 4Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 5Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 6Amgen Announces Collaboration With Roche On Cancer Immunotherapy Study With Investigational Medicines Talimogene Laherparepvec And Atezolizumab 7Pivotal Therapeutics Announces First Quarter Financial Results 2Pivotal Therapeutics Announces First Quarter Financial Results 3Pivotal Therapeutics Announces First Quarter Financial Results 4Pivotal Therapeutics Announces First Quarter Financial Results 5
... (Nasdaq: GNTA ) today announced financial results and progress,for ... noted,significant recent milestones, including:, -- ... -- New oral product, G4544, completes initial Phase ... -- Tesetaxel, a leading oral taxane, becomes new ...
... Committee Recommends FDA Approve Novel Anesthesia Drug to Reverse Muscle ... ... Schering-Plough,(NYSE: SGP ) today announced that the U.S. ... Support has recommended,sugammadex for approval. After reviewing data on the ...
Cached Medicine Technology:Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 2Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 3Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 4Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 5Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 6Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 7Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 8Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 9Genta Incorporated Announces Fourth Quarter and Year End 2007 Financial Results and Corporate Highlights 10FDA Advisory Committee Unanimously Recommends U.S. Approval of Sugammadex, the First and Only Selective Relaxant Binding Agent 2FDA Advisory Committee Unanimously Recommends U.S. Approval of Sugammadex, the First and Only Selective Relaxant Binding Agent 3FDA Advisory Committee Unanimously Recommends U.S. Approval of Sugammadex, the First and Only Selective Relaxant Binding Agent 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: