Navigation Links
Rash Due to Lung Cancer Drug May Be Linked to Better Survival
Date:12/20/2010

MONDAY, Dec. 20 (HealthDay News) -- Lung cancer patients who develop a rash after treatment with the drug cetuximab (Erbitux) have better outcomes, according to a new study.

German researchers compared hundreds of patients with non-small cell lung cancer who received chemotherapy plus cetuximab and hundreds of patients who received chemotherapy alone. About 70 percent of the patients who received the combination therapy developed an acne-like rash within the first three weeks of treatment.

Compared to other patients, those who developed the rash lived longer (15 months vs. 8.8 months), had better progression-free survival (5.4 months vs. 4.3 months) and had a higher response rate (44.8 percent vs. 32 percent), according to the report by Dr. Ulrich Gatzemeier, from Hospital Grosshansdorf in Germany, and colleagues.

The findings, published online Dec. 19 in The Lancet Oncology, suggest that the early appearance of a skin rash may help identify patients who would be most likely to respond to treatment with cetuximab and gain the greatest survival benefit, the researchers noted.

The study authors concluded that further clinical trials are needed "to verify this finding and assess it fully in the context of possible clinical application."

In a commentary accompanying the report, Dr. Francesco Perrone from the Istituto Nazionale Tumori in Naples, Italy, added: "The only way to verify the hypothesis that skin rash predicts the benefit of cetuximab is a randomized trial that compares interruption versus continuation of cetuximab in patients with skin rash after three weeks of treatment with cetuximab and chemotherapy."

The findings, Perrone continued, "must be validated prospectively before we consider the introduction of cetuximab into clinical practice for the treatment of patients with advanced non-small cell lung cancer."

More information

The American Cancer Society has more a
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Enhancing arrest of cell growth to treat cancer in mice
2. Paxil Blocks Tamoxifen, Lowers Survival Odds Against Breast Cancer
3. The National Coalition for Cancer Survivorship Joins the Commission on Cancer
4. Low forms of cyclin E reduce breast cancer drugs effectiveness
5. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
6. Soft drinks may increase risk of pancreatic cancer
7. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
8. Genes Play Role in Prognosis With Non-Small Cell Lung Cancers
9. Single gene mutation induces endometrial cancer
10. Certain genetic profiles associated with recurrence-free survival for non-small cell lung cancer
11. Molecular pathways linked to sex, age affect outcomes in lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rash Due to Lung Cancer Drug May Be Linked to Better Survival
(Date:12/26/2014)... 26, 2014 Parker & Sons, ... best in heating, cooling and plumbing contractor services ... emergency services in 2014 with regard to air-conditioning ... Arizona is known for its incredibly hot summers. ... the intricacies and details of a wide variety ...
(Date:12/25/2014)... TX (PRWEB) December 26, 2014 The ... to 2023” focuses on the current treatment landscape, unmet ... cancer market. TS-1 is an anti-cancer drug which is ... orally and is also used for treating gastric cancer ... and otastat potassium. The drug was first approved in ...
(Date:12/25/2014)... 2014 The short film “Color of Honor” ... honor of a true 9/11 hero, Welles Remy Crowther. It ... the 24 hours of Nuremberg International Short Film Festival and ... Actress, screenwriter and director Luciana Lagana plays the ... with her husband, Gregory Graham - Graham plays ...
(Date:12/25/2014)... December 25, 2014 Recently, LunaDress.co.uk has updated its ... and related accessories. Now, all of the models at LunaDress.co.uk come ... a groom lifts the wedding veil can turn out to be ... charm. A wedding veil can always bring surprise to a wedding. ... on how to choose veils for a big day . ...
(Date:12/25/2014)... Dennis Thompson HealthDay Reporter ... could be closing in on a "fountain of youth" drug ... health of older adults, a new study suggests. Seniors ... a drug that targets a genetic signaling pathway linked to ... report. The experimental medication, a version of ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:LunaDress Provides Professional Tips On Shopping Wedding And Prom Dresses 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3
... Netherlands, May 8 LyondellBasell Industries,has completed ... of its management systems at its plants ... MonoPropyleneGlycol USP/EP,(MPG-USP/EP) is produced., HACCP is ... preventing,food safety hazards. The comprehensive nature of ...
... 8 PennWell Corporation is launching a,third dental ... -,7th, 2008. Registration is now open and available ... use,leading-edge technology to bring dental professionals together with,colleagues ... computer., "DDS Tech Fair is designed to ...
... Academies Keck FUTURES INITIATIVE announced today the recipients of ... research on aging and healthspan -- the period of ... The 15 projects chosen represent a wide range ... of the fifth annual FUTURES conference, "The Future of ...
... physicians across the country who lead small practices are ... FACP, president of the American College of Physicians (ACP) ... Dr. Dale emphasized that practices are medicines small businesses, ... Medicares flawed reimbursement rates and formulas. , Approximately 20 ...
... non-profit youth,development organization, has been awarded a $25,000 grant ... launched Healthy Communities Program,launched today in conjunction with District ... General Mills Foundation and the Mayor,s Commission,on Food and ... to focus on,helping children eat healthy and stay physically ...
... people discover mold on their bread, they immediately throw ... the tiny fungus. A University of Missouri scientist, along ... mechanism in the reproductive cycle of a certain species ... abnormalities by silencing unmatched genes during meiosis (sexual reproduction). ...
Cached Medicine News:Health News:Raising the Bar on MonoPropyleneGlycol USP/EP 2Health News:PennWell Announces DDS Tech Fair 2Health News:Keck Futures Initiative awards $1M for 15 research projects 2Health News:Keck Futures Initiative awards $1M for 15 research projects 3Health News:Keck Futures Initiative awards $1M for 15 research projects 4Health News:Keck Futures Initiative awards $1M for 15 research projects 5Health News:Keck Futures Initiative awards $1M for 15 research projects 6Health News:ACP says Medicare cuts will hurt physicians in small practices 2Health News:Brainfood Awarded $25,000 Grant from General Mills Foundation through DC Mayor Fenty's New Health Communities Program 2Health News:Bread mold may hold secret to eliminating disease-causing genes 2
(Date:12/24/2014)... , Dec. 24, 2014  Commonwealth Cornerstone Group (CCG) today ... Credits transaction on Tuesday to help fund the expansion and ... in Sharon . PHN ... Pennsylvania . It is the largest employer in ... than 150 people on staff. Currently, PHN Sharon ...
(Date:12/24/2014)... 2014  Conkwest, Inc., the Natural Killer Cell ... Killer (NK) cell-line platform, Neukoplast® (NK-92™) as an ... , NantWorks founder, physician scientist and biotechnology entrepreneur, ... approximately $48 million of the Company,s Class A ... will be named Co-Chairman of the Conkwest Board ...
(Date:12/24/2014)... 23, 2014 Echo Therapeutics, Inc. (NASDAQ: ... focused on skin permeation, continuous glucose monitoring and ... Hollander has been appointed Chief Executive Officer ... than 20 years of experience in the medical ... recently served as Vice President, Business Development, Otsuka ...
Breaking Medicine Technology:Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 2Commonwealth Cornerstone Group Announces $8 Million in Tax Credits to Expand and Consolidate Healthcare Services in Sharon 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 2Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 3Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 4Conkwest Announces $50m In Strategic Investments And Appoints NantWorks Founder, Dr. Patrick Soon-Shiong As Co-Chairman Of The Board 5Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3
... new approach to research, along with public policies that ... diseases with potentially devastating personal and financial consequences, such ... Ph.D., chairman, president and CEO of Eli Lilly and ... Thursday in London during a keynote address at The ...
... Mass., Feb. 9, 2011 New England Biolabs ... Journal of Visualized Experiments (JoVE) for the EpiMark™ ... suite of new and validated products designed to ... protocol describes a 3-step, PCR-based assay to identify ...
Cached Medicine Technology:Lilly CEO Says Industry, Public Policy Must Pave Way For Innovation 2Lilly CEO Says Industry, Public Policy Must Pave Way For Innovation 3New England Biolabs Releases JoVE Video Protocol Highlighting Assay to Quantitate 5-hmC in Epigenome 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: