Navigation Links
Rare skin tumor responds better to treatment than melanoma
Date:2/2/2009

lar to malignant melanoma by surgically removing the lesion and in many cases also with a sentinel lymph node biopsy. The sentinel lymph node biopsy involves the removal and evaluation of one or a few lymph nodes nearest the skin lesion to determine whether the skin lesion has spread to the lymph nodes.

Ludgate and his team analyzed U-M's unique comprehensive melanoma database that has been collecting data for almost two decades for all cases of ASTs of uncertain biological potential between 1994 and 2007. Data were examined to learn the clinical features of a patient, whether the patient underwent a lymph node biopsy and the histological features of the tumor.

Of the 67 patients in the study, 57 had undergone wide excision and sentinel lymph node biopsy, and 27 biopsies were positive.

All 27 of AST patients with positive sentinel node biopsy are alive and disease-free at an average of about 44 months follow-up, researchers note.

"If AST were a form of melanoma, we would expect that at least some of the patients would have had the AST recur throughout the body by this time" Ludgate explains. "This study provides evidence that although ASTs have some features of melanoma microscopically, they do not behave as aggressively."

These findings can be interpreted in three ways, Ludgate says. "The first is that AST is not cancer at all, but has some ability to spread. The second possibility is that because ASTs often occur in younger people with intact immune systems, the body is able to successfully fight off the beginnings of metastatic disease. The third possibility is that AST is potentially deadly but removal of the primary AST lesion and the sentinel lymph node biopsy is curative."

Each of these possibilities is considered in the treatment strategy developed collectively as a result of this study. One result of this new strategy is that not every patient with AST must undergo a complete lymph node dissection or
'/>"/>

Contact: Katie Vloet
kgazella@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford study prevents pancreatic tumor growth in mice by inhibiting key protein
2. Oncogene inhibits tumor suppressor to promote cancer: Study links B-RAF and LKB1
3. Novartis Oncology Launches GIST Alliance™ for Healthcare Professionals Treating Gastrointestinal Stromal Tumors
4. Breast cancer drug shows promise for treating, preventing progestin-dependent tumors
5. New laser for neurosurgery allows greater precision and efficiency for removal of complex tumors
6. Gene may lead to early onset of brain tumor
7. New Institute Targets Brain Tumor Survival
8. New institute targets brain tumor removal
9. New criteria for measuring tumor size and progression will help ease workloads in clinical trials
10. David Welch, Friend, Advocate, Inspiration, Loses Courageous Battle to Brain Tumor
11. Gene therapy eliminates brain tumors through selective recruitment of immune cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... severe illness and even death are likely to result ... influenza. Now, however, a team of researchers based at ... the order of infection, the bacteria Streptococcus pneumoniae ... bad case of the flu. , The researchers ... as a bacterial virulence factor, might protect macrophagesa type ...
(Date:7/10/2014)... cancer were more likely to be diagnosed with ... and survived for shorter times than prostate cancer ... has found. , The negative outcomes may be ... against the mentally ill, depression,s impact on biological ... in his general health and disinterest in receiving ...
(Date:7/10/2014)... who experience hot flashes are unlikely to talk much ... silent suffering if they are willing to try ... University case study., After seven weeks of hypnotic relaxation ... following prostate cancer surgery showed a drastic decrease not ... in sleep quality, according to the study., The Baylor ...
(Date:7/9/2014)... the first time, researchers have access to detailed information ... health care. A new study, called Our Health Counts, ... challenges faced by urban Aboriginal people in Canada ... The findings, published today in BMJ Open , ... the general population. , Researchers interviewed 554 First Nations ...
(Date:7/9/2014)... active in almost all types of cancer sends the ... help fuel a tumour,s uncontrolled growth, new research suggests. ... identified a molecular trigger responsible for ratcheting up activity ... that makes the building blocks cancer cells need to ... pathway, called SREBP, controls the flow of messages to ...
Breaking Medicine News(10 mins):Health News:Bacterial colonization prior to catching the flu may protect against severe illness 2Health News:Depressed men with prostate cancer are diagnosed later stage, get less effective therapies 2Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 2Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 3Health News:Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about 4Health News:Urban Aboriginal people face unique health challenges 2Health News:Signal may send cancer's cellular factories into overdrive 2
... $10,000 Donation to Local Food Bank, WASHINGTON, Oct. ... Roundy,s Supermarkets Inc. have launched a,campaign to demonstrate the ... campaign will be conducted in 155 Pick ,n Save, ... 7-31, 2007., Shoppers can sample a smoothie recipe ...
... Agency recently honored Proctor & Gamble, Cincinnati, Ohio, ... risks., The company accepted a 2007 Children,s ... with the Children,s Environmental Health,Workshop in Washington D.C. ... to ensure clean drinking water for children by ...
... MARKET FORECAST FOR THE DRUG, WALTHAM, Mass., Oct. ... is available to discuss the impact of the Food ... integrase inhibitor drug which blocks the ability of the ... inhibitors are a novel class of HIV drugs aimed ...
... Central venous catheters are commonly used to provide permanent ... inserting a catheter through large vessels, has been commonly ... in Hemodialysis International finds that this treatment may block ... vena cava syndrome (SVC syndrome), a highly serious complication ...
... pleased to,announce the launch of a 5-year cooperative agreement ... of the program is to strengthen,the breadth and depth ... health informatics and encourage new explorations of innovations,at the ... to:, -- Train and educate the public health ...
... Ariz., Oct. 12 Langford IC Systems, Inc.,announces ... the only,Parametric Release(TM) liquid chemical instrument processor. The ... system that cleans and,reprocesses instruments at the point ... hospitals, medical clinics, and in any medical setting ...
Cached Medicine News:Health News:AISI and Roundy's Supermarkets Inc. Launch Program to Educate Shoppers on the Nutritional and Safety Benefits of Canned Food 2Health News:Proctor & Gamble Receives EPA Children's Environmental Health Excellence Award 2Health News:Impending FDA Approval Decision on the First HIV Integrase Inhibitor Can Have Significant Impact for Patients 2Health News:AMIA Announces Partnership with CDC to Enhance Public Health Informatics 2Health News:FDA Grants Clearance to Langford IC Systems, Inc. 2Health News:FDA Grants Clearance to Langford IC Systems, Inc. 3
(Date:1/15/2014)... 2014 AARP Foundation today announced it has established a ... the severe cold weather that has gripped much of the ... in need; so to support these emergency relief efforts AARP ... which could mean up to $500,000 in aid. The matching ...
(Date:1/15/2014)... Corporation (the "Company") (NASDAQ: CLSN ) today ... to purchase an aggregate of approximately $15 million of ... offering, led by a dedicated health care fund. ... these investors pursuant to which the Company agreed to ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) ... approval condition to the announced tender offer for all of the ... a result of the waiver, the transaction is no longer conditional ... on January 24, 2014 following the currently scheduled expiration time, subject ...
Breaking Medicine Technology:AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: