Navigation Links
Rare skin tumor responds better to treatment than melanoma
Date:2/2/2009

lar to malignant melanoma by surgically removing the lesion and in many cases also with a sentinel lymph node biopsy. The sentinel lymph node biopsy involves the removal and evaluation of one or a few lymph nodes nearest the skin lesion to determine whether the skin lesion has spread to the lymph nodes.

Ludgate and his team analyzed U-M's unique comprehensive melanoma database that has been collecting data for almost two decades for all cases of ASTs of uncertain biological potential between 1994 and 2007. Data were examined to learn the clinical features of a patient, whether the patient underwent a lymph node biopsy and the histological features of the tumor.

Of the 67 patients in the study, 57 had undergone wide excision and sentinel lymph node biopsy, and 27 biopsies were positive.

All 27 of AST patients with positive sentinel node biopsy are alive and disease-free at an average of about 44 months follow-up, researchers note.

"If AST were a form of melanoma, we would expect that at least some of the patients would have had the AST recur throughout the body by this time" Ludgate explains. "This study provides evidence that although ASTs have some features of melanoma microscopically, they do not behave as aggressively."

These findings can be interpreted in three ways, Ludgate says. "The first is that AST is not cancer at all, but has some ability to spread. The second possibility is that because ASTs often occur in younger people with intact immune systems, the body is able to successfully fight off the beginnings of metastatic disease. The third possibility is that AST is potentially deadly but removal of the primary AST lesion and the sentinel lymph node biopsy is curative."

Each of these possibilities is considered in the treatment strategy developed collectively as a result of this study. One result of this new strategy is that not every patient with AST must undergo a complete lymph node dissection or
'/>"/>

Contact: Katie Vloet
kgazella@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stanford study prevents pancreatic tumor growth in mice by inhibiting key protein
2. Oncogene inhibits tumor suppressor to promote cancer: Study links B-RAF and LKB1
3. Novartis Oncology Launches GIST Alliance™ for Healthcare Professionals Treating Gastrointestinal Stromal Tumors
4. Breast cancer drug shows promise for treating, preventing progestin-dependent tumors
5. New laser for neurosurgery allows greater precision and efficiency for removal of complex tumors
6. Gene may lead to early onset of brain tumor
7. New Institute Targets Brain Tumor Survival
8. New institute targets brain tumor removal
9. New criteria for measuring tumor size and progression will help ease workloads in clinical trials
10. David Welch, Friend, Advocate, Inspiration, Loses Courageous Battle to Brain Tumor
11. Gene therapy eliminates brain tumors through selective recruitment of immune cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/4/2015)... The medical device landscape is littered with ... or ignored or didn't know – the cardinal rule ... physician input before proceeding to design and develop a ... become so enamored of an innovative concept that they ... the device?” says Dr. Kathryn Stecco , physician, ...
(Date:3/3/2015)... (PRWEB) March 04, 2015 ... facilities design and construction event for New England, ... Massachusetts announced key building envelope related workshops. Sessions ... Workshops include: , Curtain Walls for ... many health care and laboratory facilities are often ...
(Date:3/3/2015)... Anik Singal's Profit Academy - ... marketers has become the talk of the town ... surrounding the course's general release has garnered the ... her to review the program's content and publish ... biggest keys to success with Internet marketing is ...
(Date:3/3/2015)... 2015 NOVAtime Technology, Inc. ( ... and Attendance / Workforce Management solutions, announced that ... SaaS Workforce Management / Time and Attendance ... , Since 2004, Innovative Services’ mission has ... the best quality of life. The company is ...
(Date:3/3/2015)... On February 21st, the rooftop of the Beverly ... day-long event that features a gathering of providers of ... by Debbie Durkin and Durkin Entertainment, Los Angeles’ leading ... Lounge saw many notable attendees. Among them was Chase ... Flash, Star Trek: Deep Space Nine and many, many ...
Breaking Medicine News(10 mins):Health News:Want to Succeed in Medical Technology? Don't Innovate in a Vacuum 2Health News:Want to Succeed in Medical Technology? Don't Innovate in a Vacuum 3Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 2Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 3Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 4Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 5Health News:Building Envelope Code and Regulation Sessions at MED-Ed Facilities 6Health News:Anik Singal's Profit Academy - Review Of New IM Training Program Released 2Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 2Health News:Innovative Services, Inc. Successfully Migrates to Cloud-Based NOVAtime Workforce Management Solution to Support Growth and Improve Payroll Processing Time 3Health News:Hollywood Star Chase Masterson and Choices Recovery Discuss Substance Abuse and Treatment at 2015 Oscars 2
... of genes that appear to raise the risk of adult-onset ... who is likely to develop the disease. ,An ... that are linked to the condition, which is caused both ... obesity and smoking. The five variants are thought together to ...
... with dengue is being held up as an example of ... ,Following a three-day meeting of a group of ... ,A roadmap for 2007 was laid out to ... ,Singapore's director-general of Public Health, Khoo Seow Poh, says ...
... smoke could face a higher heart disease risk, says a ... hand smoke exposure through levels of a nicotine by-product in ... the participants' recall of exposure. ,However, in the ... Nottingham, and other researchers measured the level of cotinine in ...
... delivered with the help of a Caesarean section or c-section, ... walls. ,Originally a life-saving procedure for mother ... on the safe side." ,Many women know ... reasons some women have no choice but to have a ...
... many of the same health problems as tobacco smoke, such ... to a new study by researchers at Yale School of ... illicit drug in the United States, and abuse of the ... today’s Archives of Internal Medicine. First author Jeanette M. Tetrault, ...
... working very long hours is linked to an ... safety problems for particular groups// of industrial employees, ... stronger effect on overall health, safety, and productivity, ... Occupational and Environmental Medicine, official publication of the ...
Cached Medicine News:Health News:Gene Test to Spot Adults Who Might Get Diabetes 2Health News:More Women Opting for Caesarean, Unaware of Consequences 2Health News:Long-term Marijuana Smoking Leads to Respiratory Complaints 2Health News:Concerns About Working Overtime May Be Misplaced 2
(Date:3/3/2015)... , March 3, 2015   VWR ... products, services and solutions, announced today the expansion ... Inc. (NEB®). This agreement allows VWR increased access ... support in the U.S. and Puerto Rico.  In ... products through VWR,s e-business platform, sales organization, and ...
(Date:3/3/2015)... Israel , March 3, 2015 /PRNewswire/ ... the "Company"), an Israeli biopharmaceutical company primarily ... for inflammatory and gastrointestinal diseases, including gastrointestinal ... , RedHill,s Chief Business Officer, will be ... online event, on Thursday, March 5, 2015, ...
(Date:3/3/2015)... , March 3, 2015  The eleventh annual Tucson ... of the world,s top research scientists, academics, oncologists and ... theories and learn about new outcomes in patient treatments ... Each year Ventana Medical Systems, Inc. ... sponsors the Tucson Symposium at the Hilton El Conquistador ...
Breaking Medicine Technology:VWR Announces Expansion of Distribution Agreement with New England Biolabs 2RedHill Biopharma to Present at VirtualInvestorConferences.com Online Event on March 5, 2015 2RedHill Biopharma to Present at VirtualInvestorConferences.com Online Event on March 5, 2015 3RedHill Biopharma to Present at VirtualInvestorConferences.com Online Event on March 5, 2015 4Global scientific collaborators to explore latest pathology and oncology advancements at Tucson Symposium 2
... Wash., March 1, 2011 Iverson Genetic Diagnostics, Inc. announced ... dverse Event R eduction f or A ... itiation) was initiated in major hospital systems nationwide to assess ... dose for individual patients to reduce their risk of serious ...
... GASTONIA, N.C., Feb. 28, 2011 Today, CaroMont Health ... Island Lake, NC. The acronym CLiC stands for convenient, ... 12 hours a day (8:30am-8:30pm), seven days a week, ... (Photo:   http://photos.prnewswire.com/prnh/20110228/CL56242 ) CLiC will ...
Cached Medicine Technology:WARFARIN Study Launched to Assess Impact of Genetic Testing in Reducing Hospitalizations and Deaths Caused by Warfarin 2WARFARIN Study Launched to Assess Impact of Genetic Testing in Reducing Hospitalizations and Deaths Caused by Warfarin 3CaroMont Health Opens Immediate Care Clinic in Mountain Island Lake 2CaroMont Health Opens Immediate Care Clinic in Mountain Island Lake 3
... The Slim-LOCTM Plate is a ... intervertebral body fixation. The Slim-LOC is ... design, modified by current market technology. ... versatility & integrated instrumentation. Reduced width ...
... The product is intended for supportive ... following anterior fusion. The device utilizes ... load sharing is enhanced through dynamic ... Anterior cervical single level interbody fusion. ...
... all patient follow-ups. This allows your office to ... in your office (analogous to putting a Holter ... interpreting the reports PDSHEART provides you. PDSHEART is ... to your reports 24 hours per day via ...
... been providing excellence in Ambulatory ECG ... of physicians in the diagnosis and ... conditions each year. State-of-the-art equipment and ... the highest standard of customer service ...
Medicine Products: