Navigation Links
Rare pancreatic cancer patients may live longer when treated with radiation therapy

Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy, according to a largest of its kind study in the November 15 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

PNT is a very rare form of pancreatic cancer that can stay confined to the liver and often cause death from liver damage. Since it is usually unable to be removed by surgery, external beam radiation therapy (EBRT) is an attractive option for managing the disease, but the role of EBRT is largely unknown because of the low incidence of this tumor type and, as a result, very few related studies.

Researchers at the departments of radiation oncology and internal medicine, division of hematology/oncology and comprehensive cancer center biostatistics unit at the University of Michigan in Ann Arbor, Mich., sought to determine if PNTs are not as resistant to radiation therapy as was previously thought.

Records from 36 patients with PNTs who were treated between 1986 and 2006 with radiation therapy to 49 sites were reviewed and it was found that in 39 percent of patients the tumor shrunk to less than half its pretreatment size after being treated with EBRT. Also, radiation therapy treatments achieved high rates of local control and 90 percent of patients experienced palliation of symptoms such as pain, nausea, vomiting or obstructive jaundice.

Theodore S. Lawrence, M.D., Ph.D., FASTRO, an author on the study and chair of the University of Michigan Department of Radiation Oncology, said, "While this particular type of cancer can have potentially devastating effects on a patient, this study proves that using external beam radiation therapy may permit these patients to live longer, which is a very positive breakthrough for a disease that can have very negative outcomes."


Contact: Beth Bukata
American Society for Radiation Oncology

Related medicine news :

1. Is type 2 diabetes mellitus a risk factor for gallbladder, biliary and pancreatic cancer?
2. Congressman Fattah Supports Legislation to Address More Funds for Pancreatic Cancer Research
3. Hepatitis B does not increase risk for pancreatic cancer
4. Stem Cells Being Tested to Fight Pancreatic Cancer
5. New Hope for Treatment of Pancreatic Cancer
6. Pancreatic cancer: Researchers find drug that reverses resistance to chemotherapy
7. The Lustgarten Foundation Expresses Condolences as Pancreatic Cancer Claims Life of Myles Brand
8. The Lustgarten Foundation Says Patrick Swayzes Death Highlights the Need for Increased Research into Early Diagnosis and Treatment of Pancreatic Cancer
9. The Pancreatic Cancer Action Network Is Saddened by the Death of Actor Patrick Swayze
10. MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer
11. Pancreatic Cancer Deaths Higher for Blacks
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... For the first time, Vitalalert is donating ... Beat ” campaign. The partnership between the two groups began in 2014 with Vitalalert ... cause. , MAP International was founded in 1954 and is an international Christian-based health ...
(Date:11/25/2015)... ... 2015 , ... Dental professionals who would like to become more proficient on ... Dr. Mark Iacobelli’s Advanced Implant Mentoring (AIM) CE course. Courses will be held on ... co-founders of Advanced Implant Mentoring (AIM), Dr. Iacobelli and Dr. D’Orazio are proud to ...
(Date:11/25/2015)... ... 2015 , ... The McHenry County law firm of Botto Gilbert Lancaster, ... Francisco J. Botto and Alex C. Wimmer. Attorneys Botto and Wimmer represented the claimant ... (2d) 130884WC. , According to court documents, Adcock testified that on May 10, 2010 ...
(Date:11/25/2015)... ... November 25, 2015 , ... SCOTTSDALE, ... facial plastic surgeon specializing in both surgical and non-surgical treatments, announced the expansion ... at Hobgood Facial Plastic Surgery. , Highly trained and nationally recognized for ...
(Date:11/25/2015)... ... 25, 2015 , ... In an ongoing Clinical Study conducted by an independent ... UV Angel is evaluating the efficacy of its product and its disinfection protocol. This ... beds) from May 2014 through October 2015 at a 360-bed, acute-care, academic medical center ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... UTRECHT , Nederland, November 26, 2015 ... --> Een nieuwe aanpak combineert ... van gevorderde kanker. ... -->      (Photo: ... van het Leids Universitair Medisch Centrum (LUMC) ...
(Date:11/26/2015)... , November 26, 2015 3D bioprinting ... 2022, according to a new report by Grand View Research ... Disease (CKD) which demands kidney transplantation is expected to boost ... effective substitute for organ transplantation. --> 3D bioprinting ... 2022, according to a new report by Grand View Research ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Testing Market: Supplier Shares, Competitive ... offering.  --> ) ... "2016 Future Horizons and Growth Strategies ...
Breaking Medicine Technology: