Navigation Links
Rare Cells Linked to Pediatric Cancers
Date:7/15/2009

Discovery could pave the way for future targeted treatment,,,,

WEDNESDAY, July 15 (HealthDay News) -- Certain types of circulating blood cells appear to be important predictors of the spread of cancer in children, say French researchers.

They measured levels of circulating endothelial cells and endothelial progenitor cells in 23 children with localized cancer, 22 children with metastatic cancer and 20 healthy children. Circulating endothelial cells are rare cells shed from the lining of blood vessels after vascular damage. Endothelial progenitor cells are precursors of circulating endothelial cells.

"Not only were these cells found in higher levels in [cancer] patients compared to healthy volunteers, but endothelial progenitor cells were found in strikingly higher amounts in patients with metastatic disease," Francoise Farace, director of the department of biology of circulating cells at the Gustave Roussy Cancer Institute, said in a news release from the American Association for Cancer Research.

The finding that children with metastatic cancer had much higher levels of these cells than healthy children was a surprise, the researchers indicated.

"This implies that these endothelial cells most likely play a role in the development of cancer in children," Farace said. "We also observed a large range of cell levels in patients with various tumor types. In some cases, very high levels were observed, which means their role may be very important."

The study appears July 15 in Clinical Cancer Research.

Further research is needed to confirm whether these cells play a role in metastasis. If so, the researchers suggested, testing levels of the cells could improve early detection of metastatic cancer, and the cells could be targeted by new drugs to prevent the spread of cancer.

More information

The American Cancer Society has more about children and cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, July 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. DNA-damaged cells communicate with neighbors to let them know theyre in trouble
2. UCLA scientists identify how immune cells may help predict Alzheimers risk
3. Stem Cells' "Suspended" State Preserved by Key Step, Scientists Report
4. Human sperm created from embryonic stem cells
5. Genes Linked to Cholesterol in Cells Are Identified
6. Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow
7. Microscopic beads could help create designer immune cells that ignore transplanted organs
8. C-Section Stress Could Alter Babys Immune Cells
9. STEM CELLS Promotes Miodrag Stojkovic to Editor
10. Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
11. U.S. Doctors Treat Heart Attack With Mans Own Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rare Cells Linked to Pediatric Cancers
(Date:5/26/2016)... California (PRWEB) , ... May 26, 2016 , ... ... associated with discovery of thousands of defective respirators, according to court documents and ... the case of William and Becky Tyler v. American Optical Corporation, Case No. ...
(Date:5/26/2016)... , ... May 26, 2016 , ... On Memorial Day, ... women who lost their lives in military battle for the country. The nonprofit ... 2015 to provide more programs that empower independence for disabled military veterans, as well ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... MadgeTech will ... designed, engineered, and manufactured in Warner, New Hampshire at the MadgeTech headquarters. With products ... reliable monitoring solutions trusted by government agencies, including NASA. , In 2012, NASA ...
(Date:5/26/2016)... ... ... In an effort to provide hair restoration information to the widest possible audience, Dr. Parsa ... not use the app. Dr. Mohebi, the founder of Parsa Mohebi Hair Restoration, is making ... , Dr. Mohebi says, “The positive response to the Snapchat videos we started last month ...
(Date:5/26/2016)... Tampa, Fla. (PRWEB) , ... May 26, 2016 , ... ... Center (AHEC) to host a six-week smoking cessation class starting June 6 at their ... AHEC’s website, http://www.gnahec.org . , Additionally, the Lung Institute has created a free ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... Germany and GERMANTOWN, Maryland , ... QGEN ; Frankfurt Prime Standard: QIA) today announced ... agreement with Therawis Diagnostics GmbH to develop and commercialize predictive ... and market PITX2 as a marker to predict effectiveness of ... patients. "We are pleased to partner with Therawis, ...
(Date:5/25/2016)... 25, 2016 As illustrated by ... this month, the numbers and momentum of cannabis in ... into the billions, more research and development push the ... State of Legal Marijuana Markets Report  from from ArcView ... much of the increase in sector is attributed to ...
(Date:5/25/2016)... England , May 25, 2016 ... company employing the precision of circulating tumour DNA ... today announces the appointment of Professor Clive ... provide medical leadership across the clinical development programme, ... Inivata,s products help deliver significant improvements in clinical ...
Breaking Medicine Technology: