Navigation Links
Rare Cells Linked to Pediatric Cancers
Date:7/15/2009

Discovery could pave the way for future targeted treatment,,,,

WEDNESDAY, July 15 (HealthDay News) -- Certain types of circulating blood cells appear to be important predictors of the spread of cancer in children, say French researchers.

They measured levels of circulating endothelial cells and endothelial progenitor cells in 23 children with localized cancer, 22 children with metastatic cancer and 20 healthy children. Circulating endothelial cells are rare cells shed from the lining of blood vessels after vascular damage. Endothelial progenitor cells are precursors of circulating endothelial cells.

"Not only were these cells found in higher levels in [cancer] patients compared to healthy volunteers, but endothelial progenitor cells were found in strikingly higher amounts in patients with metastatic disease," Francoise Farace, director of the department of biology of circulating cells at the Gustave Roussy Cancer Institute, said in a news release from the American Association for Cancer Research.

The finding that children with metastatic cancer had much higher levels of these cells than healthy children was a surprise, the researchers indicated.

"This implies that these endothelial cells most likely play a role in the development of cancer in children," Farace said. "We also observed a large range of cell levels in patients with various tumor types. In some cases, very high levels were observed, which means their role may be very important."

The study appears July 15 in Clinical Cancer Research.

Further research is needed to confirm whether these cells play a role in metastasis. If so, the researchers suggested, testing levels of the cells could improve early detection of metastatic cancer, and the cells could be targeted by new drugs to prevent the spread of cancer.

More information

The American Cancer Society has more about children and cancer.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, July 15, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. DNA-damaged cells communicate with neighbors to let them know theyre in trouble
2. UCLA scientists identify how immune cells may help predict Alzheimers risk
3. Stem Cells' "Suspended" State Preserved by Key Step, Scientists Report
4. Human sperm created from embryonic stem cells
5. Genes Linked to Cholesterol in Cells Are Identified
6. Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow
7. Microscopic beads could help create designer immune cells that ignore transplanted organs
8. C-Section Stress Could Alter Babys Immune Cells
9. STEM CELLS Promotes Miodrag Stojkovic to Editor
10. Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
11. U.S. Doctors Treat Heart Attack With Mans Own Stem Cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rare Cells Linked to Pediatric Cancers
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... Fisher House ... Vegas Mayor John J. Lee, Nevada Military Support Alliance president Scott Bensing, and Peggy ... at the VA Southern Nevada Healthcare System. This will be the first Fisher ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... the Pittsburgh metro area, celebrates the beginning of the latest charity campaign in ... social skills through art. Donations to this worthy cause are currently being accepted ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... , The print component of “Revolutionizing Cancer Care” is distributed within ... Washington DC/Baltimore, and Seattle, with a circulation of approximately 250,000 copies and an ...
(Date:2/12/2016)... ... February 12, 2016 , ... A lot has been reported about ... president has access to health and wellness resources most Americans could ever dream of ... individual has a schedule as frenetic as the U.S. President. , In honor ...
(Date:2/12/2016)... ... February 12, 2016 , ... Basketball is a game for everyone, not just ... PoppersTM series, sign language translation is featured in the top right of the screen. ... PoppersTM lessons has a sign language translator to teach kids the game and how ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... - Cardiac Marker Diagnostic ... and Cancer Therapy. - European Point of Care ... - Key Diagnostic Testing Markets. - Molecular ... Genetic Testing. - Molecular Diagnostics in Infectious Disease ... Diagnostic Products World Markets. - Point of Care ...
(Date:2/11/2016)... 11, 2016 Laboratory glassware and ... laboratories. These may range from microscope slides to large ... made from borosilicate glass because of its low weight ... other hand, started gaining popularity over the past decade ... replace glass with plastic in several applications due to ...
(Date:2/11/2016)... --  Health 2.0 , the premiere showcase and catalyst ... " 10 Year Global Retrospective ", a platform to ... ten years.   --> ... served as the preeminent thought-leader in the health tech ... companies, innovators, and patient-activists through an array of events ...
Breaking Medicine Technology: