Navigation Links
Rare, Severe Form of Morning Sickness Appears to Be Genetic
Date:11/16/2010

TUESDAY, Nov. 16 (HealthDay News) -- A rare, but severe and potentially life-threatening form of morning sickness, called hyperemesis gravidarum, may be hereditary, researchers say.

Each year about 60,000 pregnant women in the United States are hospitalized due to hyperemesis gravidarum (HG), marked by chronic vomiting so frequent and severe that it can cause weight loss, dehydration and psychological trauma. The condition, although almost always treatable, can in rare cases lead to complications that force women to terminate their pregnancies.

The new study of 650 women included those who had been diagnosed with HG and a control group of women who had had at least two pregnancies and had not had HG. Women with sisters who had HG were 17.3 times more likely to develop the condition, the investigators found.

Women with HG were more than five times more likely than the control participants to have a sister who had severe morning sickness or HG. In addition, 33 percent of women with HG had an affected mother, compared with 8 percent of controls, according to the report.

Among women who had information about their grandmothers' pregnancies, 18 percent of HG patients had a maternal grandmother with HG and 23 percent had a paternal grandmother who had had the condition, the study authors noted.

"Pregnant women with a family history of extreme nausea in pregnancy should be aware that they may have it too, and health care providers should take a family history of nausea in pregnancy at the first visit with an obstetrician," lead author Marlena Fejzo, an assistant professor of hematology-oncology at the David Geffen School of Medicine at the University of California, Los Angeles, said in a UCLA news release. "The high familial prevalence strongly suggests a genetic component to this condition," Fejzo added.

"Because the incidence of hyperemesis gravidarum is most commonly reported to be 0.5 percent in the population, and the sisters of cases have as much as an 18-fold increased familial risk for HG compared to controls, this study provides strong evidence for a genetic component to extreme nausea and vomiting in pregnancy," the study authors concluded.

The study, led by researchers from the University of California, Los Angeles and the University of Southern California, was released online in advance of publication in an upcoming print issue of the American Journal of Obstetrics & Gynecology.

More information

The U.S. National Library of Medicine has more about hyperemesis gravidarum.

-- Robert Preidt

SOURCE: University of California, Los Angeles, news release, Nov. 4, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Global media campaign finds hidden children with rare, fatal aging disorder
2. Radiation does not improve survival for rare, invasive bladder cancer
3. Severe Acne May Up Suicide Risk: Study
4. A comparison of severe outcomes during the waves of pandemic (H1N1) 2009
5. Major clinical trial prompts call for change to treatment guidelines for severe malaria worldwide
6. Discovery shows promise against severe side effects
7. Severely injured should go directly to trauma center: Research
8. Johns Hopkins researchers turn off severe food allergies in mice
9. New treatment for severe aortic stenosis shown to save lives, Stanford researchers say
10. Disc Battery Ingestion May Cause Severe Injuries in Babies
11. Gene Rx May Fight Severe Blood Disorder
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rare, Severe Form of Morning Sickness Appears to Be Genetic
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s National ... 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. 12-15. ... for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, M.D., ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned and ... 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness will ... Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry Autograph ...
(Date:10/12/2017)... ... October 12, 2017 , ... In ... taxes a year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, ... overseas retirement havens have extremely low property-tax rates, which contributes to the relatively ...
(Date:10/12/2017)... ... October 12, 2017 , ... Farm ... California Berkeley, and other leading institutions in announcing the launch of the ... change the way animals are raised for food. , Founding members of the ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017   Montrium ... Master File solutions, today—from the IQPC Trial Master ... , NL)—announced that EastHORN Clinical Services has ... clinical programs and TMF management. EastHORN, a leading ... eTMF platform to increase transparency to enable greater ...
(Date:9/19/2017)... 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, ... three leadership team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform for ... the first annual edition of its Global CSR Risk and Performance Index. ... by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points ... ... ...
Breaking Medicine Technology: