Navigation Links
Rapid and durable protection against ebola virus with new vaccine regimens
Date:9/8/2014

One shot of an experimental vaccine made from two Ebola virus gene segments incorporated into a chimpanzee cold virus vector (called chimp adenovirus type 3 or ChAd3) protected all four macaque monkeys exposed to high levels of Ebola virus 5 weeks after inoculation, report National Institutes of Health (NIH) scientists and their collaborators. The ability of the ChAd3 Ebola virus vaccine to elicit rapid protection in monkeys is notable as the world health community battles an ongoing Ebola virus disease outbreak in West Africa. While the protective effects of the single shot waned over time, two out of four inoculated animals were protected when challenged with Ebola virus 10 months after vaccination.

The research team, headed by Nancy J. Sullivan, Ph.D., of the National Institute of Allergy and Infectious Diseases Vaccine Research Center, also demonstrated increased levels of durable protection using an additional vaccine. They inoculated four macaques first with the ChAd3 Ebola vaccine, then 8 weeks later with a booster vaccine containing Ebola virus gene segments incorporated into a different vector (a poxvirus). Ten months after the initial inoculation, four out of four animals that received both shots were fully protected from infection with high doses of Ebola virus, demonstrating that the prime-boost regimen resulted in durable protection.


'/>"/>
Contact: NIAID Office of Communications
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
www.twitter.com/NIAIDNews
Source:Eurekalert  

Page: 1

Related medicine news :

1. PhysicianOne Urgent Care Announces Rapid Multi-Location Expansion
2. Theresa Caputo Tickets in Kalamazoo at Wings Stadium, Saenger Theatre in New Orleans, Kiva Auditorium in Albuquerque and Rapid City at Don Barnett Arena Now Available
3. Infitrak, Inc. and Rapid Aid, Ltd. Announce Joint Development and Distribution Agreement to Deliver Cost-effective Logistics Solutions for Temperature Controlled Markets
4. Best Drug Rehabilitation Donates $1000 to Elk Rapids High School Fundraiser Featuring Retired Detroit Lions Superstar Herman Moore
5. Postmenopausal breast cancer risk decreases rapidly after starting reg. physical activity
6. Chinese Imitations vs Medtronic and DePuy Synthes: Rapid Growth Expected in the Chinese Spinal Implant Market
7. Bio Logic Aqua Research Founder Sharon Kleyne Discusses July 2014 Fiscal Times Article on Rapid Growth of Alternative Medicine
8. Diet Doc Medical Weight Loss Programs Announces Diet Plans That Melt Excess Fat Rapidly While Teaching Patients How to Avoid Obesity
9. Single Women Motorcycle Riders In Rapid Increase
10. Atlanta Special FX Rapidly Expanding Just Opens First International Corporate Office in Jamaica
11. Rapid surgical innovation puts patients at risk for medical errors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rapid and durable protection against ebola virus with new vaccine regimens
(Date:10/18/2018)... ... October 18, 2018 , ... ... company’s automated preclinical image data analysis tool, InVivoAX™, for quantitative bioluminescence tomography ... in preclinical imaging of small animal models of human disease. The research ...
(Date:10/17/2018)... ... October 17, 2018 , ... The Myers’ have been doing this for ... office, 11141 Tampa Ave., Northridge, CA 91326. , “The Harvest Festival is another way ... time help the kids at Children’s Hospital LA,” said Kris and Keith. , The ...
(Date:10/16/2018)... ... 16, 2018 , ... Bastyr University is pleased announce that ... and Medicine’s (AIHM) Visionary Award for his passionate efforts in forging a new ... as AIHM’s recipient of the Visionary Award due to his tireless effort in ...
(Date:10/16/2018)... ... October 16, 2018 , ... ... Compliance, an attorney experienced in employment law, writes frequently on employment law matters ... she authored a chapter in the Health Care Compliance Professional's Manual titled “Navigating ...
(Date:10/16/2018)... ... October 16, 2018 , ... ... clinical research networking-technology company founded by patient-survivors, and The Avoca Group, Inc., ... the clinical trial execution process, today announced its mutual collaboration that will ...
Breaking Medicine News(10 mins):
(Date:10/17/2018)... ... October 17, 2018 , ... Dr. Dan Holtzclaw, Chief Clinical ... the use of placental based growth factors for the treatment of nerve injuries ... our DIA Dental Implant Center locations in Austin and San Antonio, we occasionally ...
(Date:10/17/2018)... ... October 17, 2018 , ... The OMNISteth™ is the first ... platform and intuitive adjustments maximize the sound quality and performance during an exam. ... on the body, which automatically adjusts the listening frequency range to the proper ...
(Date:10/16/2018)... ... October 16, 2018 , ... Citrus Valley Health Partners and Keck School ... inclusive forum on the health care ecosystem of the San Gabriel Valley. , ... evidence-based dialogues and actionable solutions aimed at transforming the way health care is provided ...
Breaking Medicine Technology: