Navigation Links
Rapid and durable protection against ebola virus with new vaccine regimens
Date:9/8/2014

One shot of an experimental vaccine made from two Ebola virus gene segments incorporated into a chimpanzee cold virus vector (called chimp adenovirus type 3 or ChAd3) protected all four macaque monkeys exposed to high levels of Ebola virus 5 weeks after inoculation, report National Institutes of Health (NIH) scientists and their collaborators. The ability of the ChAd3 Ebola virus vaccine to elicit rapid protection in monkeys is notable as the world health community battles an ongoing Ebola virus disease outbreak in West Africa. While the protective effects of the single shot waned over time, two out of four inoculated animals were protected when challenged with Ebola virus 10 months after vaccination.

The research team, headed by Nancy J. Sullivan, Ph.D., of the National Institute of Allergy and Infectious Diseases Vaccine Research Center, also demonstrated increased levels of durable protection using an additional vaccine. They inoculated four macaques first with the ChAd3 Ebola vaccine, then 8 weeks later with a booster vaccine containing Ebola virus gene segments incorporated into a different vector (a poxvirus). Ten months after the initial inoculation, four out of four animals that received both shots were fully protected from infection with high doses of Ebola virus, demonstrating that the prime-boost regimen resulted in durable protection.


'/>"/>
Contact: NIAID Office of Communications
niaidnews@niaid.nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
www.twitter.com/NIAIDNews
Source:Eurekalert  

Page: 1

Related medicine news :

1. PhysicianOne Urgent Care Announces Rapid Multi-Location Expansion
2. Theresa Caputo Tickets in Kalamazoo at Wings Stadium, Saenger Theatre in New Orleans, Kiva Auditorium in Albuquerque and Rapid City at Don Barnett Arena Now Available
3. Infitrak, Inc. and Rapid Aid, Ltd. Announce Joint Development and Distribution Agreement to Deliver Cost-effective Logistics Solutions for Temperature Controlled Markets
4. Best Drug Rehabilitation Donates $1000 to Elk Rapids High School Fundraiser Featuring Retired Detroit Lions Superstar Herman Moore
5. Postmenopausal breast cancer risk decreases rapidly after starting reg. physical activity
6. Chinese Imitations vs Medtronic and DePuy Synthes: Rapid Growth Expected in the Chinese Spinal Implant Market
7. Bio Logic Aqua Research Founder Sharon Kleyne Discusses July 2014 Fiscal Times Article on Rapid Growth of Alternative Medicine
8. Diet Doc Medical Weight Loss Programs Announces Diet Plans That Melt Excess Fat Rapidly While Teaching Patients How to Avoid Obesity
9. Single Women Motorcycle Riders In Rapid Increase
10. Atlanta Special FX Rapidly Expanding Just Opens First International Corporate Office in Jamaica
11. Rapid surgical innovation puts patients at risk for medical errors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Rapid and durable protection against ebola virus with new vaccine regimens
(Date:6/26/2019)... ... June 26, 2019 , ... Dr. Michael Snell is a ... completed his residency in Internal Medicine from Case Western Reserve University/University Hospitals of ... of Cleveland. He also has a Ph.D. in Mathematics. , Dr. Snell has ...
(Date:6/25/2019)... BIRMINGHAM, Ala. (PRWEB) , ... June 25, 2019 ... ... Family Care (AFC), the nation’s leading provider of urgent care, accessible primary care ... spent more than 15 years on the front lines of the marketing industry ...
(Date:6/25/2019)... ... June 25, 2019 , ... The Global Smile Foundation will ... July thanks to 15-year-old Kylie Azizzadeh’s efforts fundraising for the mission. She has already ... before the mission takes place on July 15, 2019. , In 2018, Kylie ...
(Date:6/24/2019)... ... 24, 2019 , ... ASRC Federal Data Network Technologies has ... (SSIS) contract. Awarded under the NITAAC CIO-SP3 Small Business GWAC, the task order ... approximately $90 million. , The Data Network Technologies team will provide systems integration ...
(Date:6/20/2019)... ... 2019 , ... SightMD (or the “Company”), a leading multi-specialty ... partnership with Northern Westchester Ophthalmology, P.C. (“NWO”) and its founding ophthalmologist Morris I. ... the Company’s first location in Westchester County to SightMD’s current footprint of 30 ...
Breaking Medicine News(10 mins):
(Date:6/24/2019)... BROOK, Ill. (PRWEB) , ... June 24, 2019 ... ... USA-made personal protective equipment designed to provide breathability and comfort for the electrical ... improve their commitment to worker safety. , The guide, titled Developing a ...
(Date:6/20/2019)... ... ... Phlexglobal today announced an important industry advisory around the new European Medicines ... 2019, and promises to have far-reaching impacts on an organization’s TMF processes, technology, and ... and going into specific detail – unusual for most guidance documents – the new ...
(Date:6/19/2019)... ... June 19, 2019 , ... One is never too old to make dreams ... Home (LAJH). Known as a destination for Los Angeles-area seniors, LAJH has an environment ... and Mildred Moccio, it is also a point of embarkation: a place from which ...
Breaking Medicine Technology: