Navigation Links
Ranibizumab Injections Reduce Retinal Swelling
Date:5/1/2008

Macular edema patients had doubling of vision angle, researcher says

THURSDAY, May 1 (HealthDay News) -- Injections of the drug ranibizumab can improve vision and reduce macular swelling caused by blockages in the retinal vein in people with macular edema, according to researchers at the Johns Hopkins Wilmer Eye Institute.

"Some patients stabilize after only a few injections, and some require several injections, but the results are very encouraging," Dr. Peter A. Campochiaro, a professor of ophthalmology and neuroscience, said in a prepared statement.

The study included 20 patients with macular edema due to central retinal vein occlusion and 20 patients with macular edema due to branch retinal vein occlusion. They were randomly selected to receive three monthly injections of ranibizumab. One month after the third injection, the average improvement was a doubling of the visual angle.

"This was a substantial improvement. Higher doses led to faster recovery that lasted somewhat longer, but had no effect on improving vision," Campochiaro said.

It's long been suspected that the protein vascular endothelial growth factor (VEGF) plays a role in blood vessel leakage and macular edema. Since ranibizumab binds VEGF, the results of this study suggest that VEGF is a major contributor to retinal vein occlusion-induced macular edema, Campochiaro said.

The results of the three-month endpoint of the study were published in the April issue of Molecular Therapy. Information about continued treatment and follow-up of patients was expected to presented Thursday at the Association of Research in Vision and Ophthalmologyannual meeting, in Fort Lauderdale, Fla.

Two phase III trials of ranibizumab are currently under way. Both are funded in part by drug maker Genentech.

More information

For more on macular edema, visit The National Eye Institute.



-- Robert Preidt



SOURCE: Johns Hopkins Medicine, news release, May 1, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Investigational New Drug Application for Fat Melting Injections Cleared by the FDA
2. Multiple corticosteroid injections in pregnant women may increase cerebral palsy
3. Consumer Safety Alert on Fat Dissolving Injections
4. Ultrasound-guided injections help ease chronic Achilles tendon pain
5. New study: Pine bark reduces perimenopausal symptoms
6. Different method of evaluating the urinary tract system reduces radiation dose
7. Saline Reduces Mortality for Brain Injury Patients
8. New approaches to reduce scarring
9. Fruity vegetables and fish reduce asthma and allergies
10. New study: Pine bark extract reduces ADHD symptoms in children
11. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/18/2017)... ... 2017 , ... Focused start-ups, not traditional health care organizations, ... the recent NEJM Catalyst Insights Report on the New Marketplace. , NEJM ... a qualified group of U.S. executives, clinical leaders, and clinicians at organizations directly ...
(Date:2/18/2017)... , ... February 17, 2017 , ... ... drvallecillos.com , Beverly Hills plastic surgeon Dr. Glenn Vallecillos ... , Dr. Vallecillos says, "Traditionally, plastic surgery has been centered around that idea ...
(Date:2/18/2017)... ... February 18, 2017 , ... ProParagraph Fashion Volume ... Studios ’ ProParagraph Fashion Volume 2 for all multi-line FCPX project needs. ... can pick and choose from hand-crafted trend-setting designs with smooth animations that will ...
(Date:2/17/2017)... , ... February 17, 2017 , ... Smiles by Seese ... Center in Davidson, NC. Dr. Brian Seese leads the practice as a skilled and ... under one roof. Smiles by Seese serves patients of all ages with excellence in ...
(Date:2/17/2017)... ... February 17, 2017 , ... The Alliance Healthcare Foundation ... to further positively impact the health and wellness of our community in San ... our duty to seriously consider releasing our assets beyond our 5% targeted distribution ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... , February 20, 2017 According to a ... (Solution, Suspension, Dry powder), Device Type (Metered dose, Dry Powder, Nebulizer)), Canister ... published by MarketsandMarkets, The market is projected to reach USD 52.37 Billion ... 6.5% during the forecast period. Continue Reading ... ...
(Date:2/20/2017)... VALLEY COTTAGE, New York , February 20, 2017 ... instruments a regularized absorption of calcium and phosphorous minerals ... pivotal role of vitamin D ingredients in maintaining a ... beverages or medicines containing vitamin D ingredients is growing ... attested the advantage of consuming vitamin D ingredients for ...
(Date:2/19/2017)... ORLANDO, Fla. , Feb. 19, 2017 /PRNewswire/ ... its revenue cycle portfolio and thought leadership at ... be receiving a category leader award from KLAS. ... Learn panel discussion focused on how market trends ... future -  particularly a sophisticated, comprehensive Patient Access ...
Breaking Medicine Technology: