Navigation Links
Ranibizumab Injections Reduce Retinal Swelling
Date:5/1/2008

Macular edema patients had doubling of vision angle, researcher says

THURSDAY, May 1 (HealthDay News) -- Injections of the drug ranibizumab can improve vision and reduce macular swelling caused by blockages in the retinal vein in people with macular edema, according to researchers at the Johns Hopkins Wilmer Eye Institute.

"Some patients stabilize after only a few injections, and some require several injections, but the results are very encouraging," Dr. Peter A. Campochiaro, a professor of ophthalmology and neuroscience, said in a prepared statement.

The study included 20 patients with macular edema due to central retinal vein occlusion and 20 patients with macular edema due to branch retinal vein occlusion. They were randomly selected to receive three monthly injections of ranibizumab. One month after the third injection, the average improvement was a doubling of the visual angle.

"This was a substantial improvement. Higher doses led to faster recovery that lasted somewhat longer, but had no effect on improving vision," Campochiaro said.

It's long been suspected that the protein vascular endothelial growth factor (VEGF) plays a role in blood vessel leakage and macular edema. Since ranibizumab binds VEGF, the results of this study suggest that VEGF is a major contributor to retinal vein occlusion-induced macular edema, Campochiaro said.

The results of the three-month endpoint of the study were published in the April issue of Molecular Therapy. Information about continued treatment and follow-up of patients was expected to presented Thursday at the Association of Research in Vision and Ophthalmologyannual meeting, in Fort Lauderdale, Fla.

Two phase III trials of ranibizumab are currently under way. Both are funded in part by drug maker Genentech.

More information

For more on macular edema, visit The National Eye Institute.



-- Robert Preidt



SOURCE: Johns Hopkins Medicine, news release, May 1, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Investigational New Drug Application for Fat Melting Injections Cleared by the FDA
2. Multiple corticosteroid injections in pregnant women may increase cerebral palsy
3. Consumer Safety Alert on Fat Dissolving Injections
4. Ultrasound-guided injections help ease chronic Achilles tendon pain
5. New study: Pine bark reduces perimenopausal symptoms
6. Different method of evaluating the urinary tract system reduces radiation dose
7. Saline Reduces Mortality for Brain Injury Patients
8. New approaches to reduce scarring
9. Fruity vegetables and fish reduce asthma and allergies
10. New study: Pine bark extract reduces ADHD symptoms in children
11. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may suffer ... unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid ... healthy coping following a traumatic event. , Trauma sufferers tend to feel a range ...
(Date:6/24/2016)... ... 24, 2016 , ... The Pulmonary Hypertension Association (PHA) learned ... receive two significant new grants to support its work to advance research and ... by recognizing patients, medical professionals and scientists for their work in fighting pulmonary ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA ... the Road To Recovery® program to drive cancer patients to and from their cancer ... ensure the highest quality of life and ongoing independence. Getting to and from ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data derived ... Assessment of major trends with potential impact on the market ... of market segmentation which comprises of sub markets, regional and ...
Breaking Medicine Technology: