Navigation Links
Ranexa(R) Significantly Reduces Incidence of CV Death, MI or Recurrent Ischemia in MERLIN TIMI-36 Patients With Elevated BNP
Date:11/5/2007

tion to the FDA seeking a new indication for first line angina and a significant reduction in cautionary language.

Ranexa is currently indicated for the treatment of chronic angina in patients who have not achieved an adequate response with other antianginal drugs, and should be used in combination with amlodipine, beta-blockers or nitrates.

Study Design

MERLIN TIMI-36 (Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary Syndromes) was a multi-national, double-blind, randomized, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of Ranexa during acute and long-term treatment in 6,560 patients (3,279 received ranolazine, 3,281 received placebo) with non-ST elevation ACS treated with standard therapy.

Within 48 hours of the onset of angina due to ACS, eligible hospitalized patients were enrolled in the study and randomized to receive intravenous Ranexa or placebo, followed by long-term outpatient treatment with Ranexa extended-release tablets or placebo. All patients also received standard therapy during both hospital-based and outpatient treatment. The doses of Ranexa extended-release tablets used in MERLIN TIMI-36 have been studied in previous Phase 3 clinical trials.

Participants in the MERLIN TIMI-36 study received current standard therapy, with approximately 96 percent of patients on aspirin, approximately 89 percent on beta blockers and approximately 82 percent on statins. Approximately 59 percent of study participants received coronary angiography during their initial hospitalization.

Previously published data from the MERLIN TIMI-36 study has shown that Ranexa was safe in this population of patients with coronary artery disease, which included nearly 1,100 patients with prior heart failure.

About CV Therapeutics

CV Therapeutics, Inc., headquartered in Palo Alto, California, is a biopharmaceutical company focused on applying molecula
'/>"/>

SOURCE CV Therapeutics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Prophylactic cranial irradiation in small cell lung cancer significantly increases survival
2. Elliott Extremely Dissatisfied With Genzyme Bid for Bioenvision; Believes Offer Significantly Undervalues Company
3. Study shows adverse drug events reported to the FDA have significantly increased
4. Rehabilitation significantly underused after heart attack and bypass surgery
5. Promising Phase 3 trial results show biologic therapy ustekinumab significantly improved psoriasis
6. National Domestic Violence Hotline Unveils 10-Year Blueprint to Significantly Reduce Domestic Violence in America
7. New Study Shows Arthritis Significantly Limits Millions of Americans Ability to Work
8. World Bank Group Report on Malaria in Africa Highlights Progress Towards Goal of Significantly Reducing Malaria Deaths
9. Psychiatrists, parents significantly differ in ADHD, psychiatric comorbidities perceptions
10. Phase II Study Shows that Nitazoxanide Significantly Improves Response to Standard of Care in Patients with Chronic Hepatitis C
11. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2015)... June 02, 2015 DiaTech Oncology, ... response profiling test to help oncologists provide personalized ... of American Pathologists (CAP) for its laboratories in ... certification is equivalent to the ‘Good Housekeeping’ seal ... chief executive officer for DiaTech. “It’s a rigorous ...
(Date:6/2/2015)... TU-Automotive Detroit is the biggest dedicated B2B ... include senior execs from GM, Chrysler, Mercedes, Ford, TomTom, ... crucial status update on the automotive technology industry and ... hours to secure one of the remaining passes. , ... tomorrow. There are 70 sessions looking across the connected ...
(Date:6/2/2015)... The health care leaders who established ... of value-based care will now offer health coverage for ... Counties. The newly launched Crystal Run Health Plans has ... Group Preferred Provider Organization (PPO) and Exclusive Provider Organization ... Partner and CEO, Hal Teitelbaum, MD, JD, MBA ...
(Date:6/2/2015)... Md. (PRWEB) June 02, 2015 ... its LCMS-8060 triple quadrupole mass spectrometer. The newest ... the LCMS-8060 combines Shimadzu’s proprietary ultrafast technologies (UF ... combination results in outstanding data quality and higher ... routine applications. , The LCMS-8060 features new technology, ...
(Date:6/2/2015)... (PRWEB) June 02, 2015 Recent findings ... indicate that while there has been a reduction in ... tripled and waterpipe vapor (hookah) usage has doubled among ... Pediatrician Dr. Russell Gombosi believes the national trend is ... could take 15 to 20 years to fully determine ...
Breaking Medicine News(10 mins):Health News:DiaTech Oncology Gains College of American Pathologists Accreditation for U.S. CorrectChemo Laboratory 2Health News:The Connected Car’s Biggest Event is Here – TU-Automotive Detroit 2015 2Health News:Leading Health Care Innovator Poised to Deliver New Health Coverage Options To The Hudson Valley Region 2Health News:Leading Health Care Innovator Poised to Deliver New Health Coverage Options To The Hudson Valley Region 3Health News:Shimadzu’s New LC-MS/MS Provides Superior Speed and Sensitivity for the Utmost in Quantitative Detection and High-Speed Analysis 2Health News:Susquehanna Health Pediatrician Warns of Adverse Effects of Teen E-Cigarette Usage 2Health News:Susquehanna Health Pediatrician Warns of Adverse Effects of Teen E-Cigarette Usage 3
... his first book in nine years and the first ... combines specific instructions for hunger-free weight loss with a ... April 28 Dr. Siegal,s Cookie Diet Book ... by physician Sanford Siegal, D.O., M.D., will be available ...
... hand sanitizer that really works at up to 50% off retail price. ... ... effort to help stop the spread of the swine flu epidemic, ReStockIt.com, ... announced that it is further discounting all of its Purell hand sanitizer ...
... it is joining the U.S. Department of Health and ... promoting National Women,s Health Week, which kicks off May ... to promote hearing health during National Hearing and Speech ... hearing test, the Across America Hearing Check Challenge ( ...
... suitable for a wide variety of markets and are used in ... are ideal in applications that require pivoting capability and where visual, ... Hinge - easier to assemble and more cost effective than the ... a demonstration and see Reell,s Torque Insert in use! , ...
... Research Group, Inc. released TreatmentTrends(R): US Nephrology, a syndicated ... US Nephrologists.In the ESA market, changes that have occurred ... while the overall use of ESAs has remained stable ... patients with Chronic Kidney Disease not on dialysis (CKD), ...
... JALISCO, Mexico, April 27 Grupo Aeroportuario del Pacifico, S.A.B. ... Company" or "GAP" today announced the following:On Sunday, April 26, ... Type A and B viruses in humans as well as ... Influenza (Swine Flu Virus). As a result of the alerts, ...
Cached Medicine News:Health News:Dr. Siegal's Cookie Diet Book by Physician, Author, and Weight-Loss Expert Sanford Siegal, D.O., M.D., Available May 22nd 2Health News:Dr. Siegal's Cookie Diet Book by Physician, Author, and Weight-Loss Expert Sanford Siegal, D.O., M.D., Available May 22nd 3Health News:Dr. Siegal's Cookie Diet Book by Physician, Author, and Weight-Loss Expert Sanford Siegal, D.O., M.D., Available May 22nd 4Health News:ReStockIt.com Greatly Cutting Prices on Hand Sanitizers, Masks to Help Combat Swine Flu Epidemic 2Health News:Better Hearing Institute Joins HHS, Office on Women's Health in Promoting National Women's Health Week and Hearing Health 2Health News:Better Hearing Institute Joins HHS, Office on Women's Health in Promoting National Women's Health Week and Hearing Health 3Health News:Better Hearing Institute Joins HHS, Office on Women's Health in Promoting National Women's Health Week and Hearing Health 4Health News:Reell Precision Manufacturing Creates a New Category of Torque Control Hinges, Check Out the Reell Torque Insert 2Health News:Product Shifts are Occurring in the Renal Anemia and Bone and Mineral Metabolism Markets According to the Most Recent TreatmentTrends(R): US Nephrology Report from BioTrends Research Group 2Health News:Grupo Aeroportuario del Pacifico, S.A.B. de C.V. Announcement Regarding Swine Flu Virus 2Health News:Grupo Aeroportuario del Pacifico, S.A.B. de C.V. Announcement Regarding Swine Flu Virus 3
(Date:6/2/2015)... 02, 2015 Research and Markets ( http://www.researchandmarkets.com/research/sn8mlw/picture_archiving ) ... Communication Systems (PACS) - Global Strategic Business Report" report ... analytics for the US, Canada , ... Asia-Pacific , Latin America , ... are provided for the period 2014 through 2020. Also, a ...
(Date:6/2/2015)... ATLANTA , June 2, 2015 ... (CSTE) joins over 150 major food companies, retailers, ... White House Forum on Antibiotic Stewardship. CSTE is ... of antibiotic-resistant bacteria, detect resistant strains, preserve the ... spread of resistant infections. CSTE continues ...
(Date:6/2/2015)... 2015 San MediTech, the industry leader in ... (CGM) for diabetics, announced its plan to attend the ... Boston on June 5 th ... Glucose Monitoring System (DGMS). The company plans to show ... innovative technologies and advancements made by Chinese medical device ...
Breaking Medicine Technology:Picture Archiving and Communication Systems (PACS) - Global Strategic Business Report 2015: User Demand Favors Integrated RIS/PACS Solutions 2San MediTech Showcases Smart Glucose Management Cloud Database at 75th ADA 2San MediTech Showcases Smart Glucose Management Cloud Database at 75th ADA 3San MediTech Showcases Smart Glucose Management Cloud Database at 75th ADA 4
... DIEGO, May 28 Aethlon Medical, Inc. (OTC Bulletin ... James A. Joyce, will present at the 2009 RedChip ... held in Fort Lauderdale, Florida. Mr. Joyce,s presentation ... June 16, 2009. The full presentation will be ...
... May 28 Amsterdam Molecular,Therapeutics (Euronext: AMT), a leader ... the European Medicines Agency has granted Orphan Drug,Designation to ... acute,intermittent porphyria (AIP). , Orphan ... market,exclusivity in Europe following marketing approval for AMT-021 if ...
Cached Medicine Technology:Aethlon Medical to Present at the 2009 RedChip Small-Cap Investor Conference on June 16, 2009 2Aethlon Medical to Present at the 2009 RedChip Small-Cap Investor Conference on June 16, 2009 3AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria 2AMT Receives EMEA Orphan Drug Designation for Acute Intermittent Porphyria 3
... memory two position control, back Illuminated ... sides, solid cast aluminum frame, armrest, ... armrests and headrest, securely locking hand ... sides, ergonomically contoured cushions with anti-viral ...
... chair for examination of the ... adjustable from 540 mm to ... an independent foot switch. The ... and incorporates a multi-adjustable headrest, ...
Heine Beta 200 Streak Retinoscope 3.5v w/Twist Lock for Welch-Allyn style handles....
Heine Beta 200 Streak Retinoscope 3.5v...
Medicine Products: