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Ragon Institute study finds HIV-specific CD4 cells that control viral levels
Date:2/29/2012

more successful suppression of viral levels suggests that inducing such responses with a vaccine may be beneficial, Streeck notes. In addition, the association of granzyme A expression with a more effective HIV-specific CD4 cell response suggests that measuring levels of the protein may allow prediction of disease outcome at the earliest stages of infection, something which is not currently possible. Future studies will need to explore the mechanisms underlying the cell-killing activities of the CD4 cell response and the functional and prognostic role of granzyme A.


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Contact: Sarah Dionne
smdionne@partners.org
617-726-6126
Massachusetts General Hospital
Source:Eurekalert

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