Navigation Links
Radioimmunotherapy After Chemo Safe for Common Lymphoma

Combo treatment improved overall survival rates in follicular non-Hodgkin lymphoma

THURSDAY, March 13 (HealthDay News) -- Radioimmunotherapy after chemotherapy is safe and effective for patients with follicular non-Hodgkin lymphoma (NHL), according to an Italian study.

It found that radioimmunotherapy with the radioactive drug yttrium-90 (90Y) ibritumombab tiuxetan, following chemotherapy with fludarabine and mitoxantrone is feasible, well-tolerated and effective in follicular NHL patients.

The study began with 61 patients who received six cycles of oral fludarabine and intravenous mitoxantrone. Of these, 57 (43 with complete response and 14 with partial response) were deemed eligible for subsequent radioimmunotherapy with 90Y- ibritumombab tiuxetan. After that treatment, 12 of the 14 partial response patients achieved complete response.

At a median follow-up of 30 months, three-year progression-free survival among the 57 patients was 76 percent, and three-year overall survival was 100 percent. Grade 3 or 4 hematological effects were noted in 36 of the 57 patients.

"This study has established the feasibility, tolerability, and efficacy of sequential treatment with six cycles of fludarabine and mitoxantrone chemotherapy followed by 90Y- ibritumombab tiuxetan as a front-line treatment for untreated patients with follicular NHL. In particular, the data represent the first evidence of a role of 90Y- ibritumombab tiuxetan after a fludarabine-containing regimen in the treatment of follicular NHL," the study authors concluded.

The findings were published online this week in The Lancet Oncology, and were expected to be published in the April print edition of the journal.

Follicular NHL -- the most common form of lymphoma in Europe and the United States -- accounts for about 30 percent of all newly diagnosed NHLs.

More information

The Lymphoma Research Foundation outlines common forms of lymphoma.

-- Robert Preidt

SOURCE: The Lancet, news release, March 12, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Work-Family Conflict Dogs Air Force Women After Deployment
2. Work-Family Conflict Dogs Air Force Women After Deployment
3. Stopping Statins After Stroke Doubles Death Risk
4. Billy Graham Home After Hospitalization:
5. Swelling After Knee Injury May Hinder Healing
6. Going on After Loss
7. Discover The Mutter Museum After Dark
8. Cialis Eases Erectile Dysfunction After Spinal Cord Injury
9. Perrigo Vice Chair Mori Arkin To Retire After 30 Years of Service
10. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
11. Pill Equals Injection in Preventing Clots After Hip Replacement
Post Your Comments:
Related Image:
Radioimmunotherapy After Chemo Safe for Common Lymphoma
(Date:11/30/2015)... (PRWEB) , ... November 30, 2015 , ... Newly reviewed ... His grandfather graduated from Tufts School of Dental Medicine in 1935. His ... for the Isola family being in dentistry as well as their commitment and passion ...
(Date:11/30/2015)... ... November 30, 2015 , ... ”Dying Words: The AIDS Reporting ... on December 1, 2015, to coincide with World AIDS Day. The multi-media project will ... covered the AIDS epidemic as he was dying of the disease. , A collaborative ...
(Date:11/30/2015)... ... November 30, 2015 , ... The American Society for Clinical ... of World AIDS Day 2015. On Nov. 30, ASCP shared its “Give a minute. ... World AIDS Day and the importance of getting tested for HIV. , ASCP has ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... last 15 years, announced today that Michigan-based Family Health Center (FHC) has selected ... over 45 years, FHC was awarded the largest Affordable Care Act grant for ...
(Date:11/30/2015)... ... November 30, 2015 , ... Medicalis, a leading ... Society of North America (RSNA) annual meeting, being held November 29 – December ... Throughout 2015, the company has completed installations for Integrated Delivery Network (IDN) ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , Nov. 30, 2015 ... global biopharmaceutical leader dedicated to delivering transformative ... underserved medical conditions, today announced the launch ... (Recombinant), PEGylated], an extended circulating half-life recombinant ... based on full-length ADVATE [Antihemophilic Factor (Recombinant)]. ...
(Date:11/30/2015)... 30, 2015 (HK$,000)For the Six Months Ended 30 September 2015 2014RestatedChange%Turnover 545,575 ... , 421,979 , 384,242 , ... 34,719 , (18.3) Medical Insurance Administration Service ... 16.1 Medical Devices and Accessories Sales , 89,645 ... Herbal Medicines Sales , 2,822 , 2,917 ...
(Date:11/30/2015)... India , November 30, 2015 ... market research report "Dental Lasers Market by Product (Soft Tissue, ... Periodontitis), End User (Hospitals, Clinics), and Geography - Global Forecast ... 224.7 Million by 2020, at a CAGR of 5.2% during ... Browse 140 market data Tables and 62 Figures spread through ...
Breaking Medicine Technology: