Navigation Links
Radio-guided surgery a safe and simple way to remove potentially cancerous nodules in the lung

Using tiny spheres of radioactive liquid to guide surgeons as they remove potentially cancerous material in the lungs is safe and more effective than other techniques, Italian researchers report at the European Multidisciplinary Conference in Thoracic Oncology (EMCTO), 24-26 February 2011, Lugano, Switzerland.

Dr Luca Bertolaccini, Dr Alberto Terzi and colleagues from Santa Croce e Carle Hospital in Cuneo, Italy, studied a technique known as radio-guided surgery in 19 patients. Each of the patients had been found to have 'single pulmonary nodules' in their lungs.

Single pulmonary nodules are solitary abnormalities in the lungs that are smaller than 3 cm in diameter. Improvements in scanning techniques such as computed tomography mean that these very small nodules are becoming more commonly found.

If such nodules are found to be malignant, then surgical treatment to remove them should be undertaken immediately, Dr Bertolaccini said. "The problem is that such lesions are usually peripheral, making bronchoscopic approaches to diagnosis unsuccessful, while the accuracy of CT-guided biopsy is hindered by the small diameter and by the patient's respiratory movements during the exam."

"Video-assisted thoracoscopic surgery (VATS) is nowadays the procedure of choice if we want to surgically biopsy and remove peripheral lung nodules. However, the use of VATS is limited by the difficulty in localizing small, deep, or non-solid lung nodules where direct finger palpation may not be possible during surgery."

Using radio-guided surgery appears to overcome these problems, the researchers found. First they inserted a needle into the lung to reach the lesion or the lung tissue surrounding it. A CT scan carried out while the needle was in place confirmed its exact position.

Next, they injected a solution of 0.3 ml of microspheres of human albumin serum labeled with Technetium󈟏m (99mTc), an element that is often used for medical tests. After injection, they used another CT scan and a technique called gamma scintigraphy --which visualizes the gamma radiation being emitted by the radioactive isotope-- to confirm precise staining of the nodule.

During surgery to remove the nodule, the researchers used a gamma detector probe to ensure they had removed all the radio-labeled tissue.

The researchers found that the technique was able to localize nodules in all 19 patients. On average it took 6 minutes to detect the nodule with the gamma probe.

Further analysis of the tissue that had been removed showed that it was a primary lung cancer in 8 cases, and a secondary lesion in 4 cases. The remaining 7 patients were found to have benign nodules. There were no complications during or after surgery.

This study shows that radio-guided surgery is a safe and simple technique for localizing single pulmonary nodules, Dr Terzi said. "Radio-guided thoracoscopy seems to be an effective procedure with fewer complications and failures than other techniques."

Commenting on the study, Dr Eric Lim, Consultant Thoracic Surgeon, Royal Brompton Hospital and Senior Lecturer, National Heart and Lung Institute, Imperial College, London, who was not involved in the study, said: "Dr Bertolaccini reports an innovative method to localize nodules that can be difficult for the surgeon to identify during routine surgery."

"This technology supports the current practice of video-assisted thoracoscopic lung resection as surgeons continuously strive to reduce incision size, pain and length of stay to increase the acceptability of surgery for lung cancer," said Dr Lim.


Contact: Vanessa Pavinato
European Society for Medical Oncology

Related medicine news :

1. Spinal Fusion Surgery May Leave Some Back Pain Patients Worse Off: Study
2. Kids With Perforated Appendix May Benefit From Early Surgery
3. Weight Loss Surgery May Cut Knee Osteoarthritis Pain
4. Views on Pitchers Elbow Surgery Called Disturbing
5. Misguided public perception on what Tommy John surgery can do apparent in new study
6. Study shows PRP, commonly used technique to improve healing, doesnt work in rotator cuff surgery
7. Inexpensive rinsing effective at reducing post-op infection following joint replacement surgery
8. National career symposium offers strategic advice to attract, advance women in surgery
9. NYU Langone Department of Orthopaedic Surgery chosen to participate in joint replacement registry
10. Scott & White Healthcare -- Round Rock performing surgery without incisions for heartburn
11. Facial Surgery May Offer Long-Term Migraine Relief for Some
Post Your Comments:
(Date:6/26/2016)... ... ... blind and certified personal trainer is helping to develop a weight loss fitness plan that ... the two major problems leading the fitness industry today:, , All ... They don’t eliminate all the reasons people quit their exercise program , ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due ... up a new, often overlooked aspect of head lice: the parasite’s ability to live away ... a common occurrence, but a necessary one in the event that lice have simply gotten ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 26, 2016 ... care operating models within the health care industry is ... financial efficiency , Deloitte offers a suite of ... business issues impacting efficient cost optimization: labor resource analysis, ... These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... Dublin ... of the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global ... including its applications in various applications. The report deals ... three main industries: pharmaceutical and biotechnology, food and beverage, ...
(Date:6/24/2016)... June 24, 2016 Research and Markets ... for Companion Diagnostic Tests" report to their offering. ... Companion Diagnostics The World Market for Companion ... medicine diagnostics. Market analysis in the report includes the following: ... (In Vitro Diagnostic Kits) by Region (N. America, EU, ROW), ...
Breaking Medicine Technology: