Navigation Links
Radiation for Childhood Cancer Might Raise Diabetes Risk
Date:8/24/2012

FRIDAY, Aug. 24 (HealthDay News) -- Some childhood cancer survivors who underwent radiation therapy may have an increased risk of developing diabetes later in life, according to a new study that is the first to make a link between radiation and diabetes.

Researchers looked at more than 2,500 people in France and the United Kingdom who had been treated for cancer in childhood between 1946 and 1985, and survived for at least 20 years after undergoing treatment.

At age 45, diabetes had been diagnosed in 6.6 percent of the patients who had undergone radiation therapy and 2.3 percent of those who did not have radiation therapy, the study found.

The researchers determined how the radiation would have been applied to patients and found that the likelihood of being diagnosed with diabetes was much higher when the tail of the pancreas had been exposed to radiation. However, radiation exposure to other parts of the pancreas did not affect diabetes risk.

This difference may be due to the fact that the tail of the pancreas contains a type of cell involved in insulin production, the researchers suggested.

The study also found that people who received higher doses of radiation to the tail of the pancreas were nearly 13 times more likely to be diagnosed with diabetes within 20 years than those who did not receive radiation therapy.

Type of cancer also affected diabetes risk. By age 45, diabetes was diagnosed in nearly 15 percent of patients who had been treated for kidney cancer, compared with an average of 3 percent for other types of cancer included in the study, such as lymphoma.

Radiation therapy for kidney cancer often focuses in the abdominal area, which increases the chance that the tail of the pancreas will be exposed to radiation, the researchers noted.

The study was published online Aug. 23 in The Lancet Oncology.

"The pancreas needs to be regarded as a critical organ when planning radiation therapy, particularly in children. Until now, the pancreas was one of the few organs not considered at risk of normal tissue complication in the French and the U.K. national guidelines for cancer radiation therapy," Dr. Florent de Vathaire of the Centre for Epidemiology and Public Health of the National Institute for Health and Medical Research, in France, said in a journal news release.

"Our findings indicate that the pancreas is an organ at risk during radiation therapy and has to be contoured when planning treatment, to ensure a radiation dose of as low as possible," de Vathaire concluded.

While the study uncovered an association between radiation therapy in childhood and diabetes later in life, it did not prove a cause-and-effect relationship.

More information

The U.S. National Cancer Institute has more about the late effects of treatment for childhood cancer.

-- Robert Preidt

SOURCE: The Lancet Oncology, news release, Aug. 22, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
2. Diagnostic Scans Tied to Radiation Risk for Gastro Patients
3. CT Scans Deliver More Radiation to Obese People: Study
4. Intensity Modulated Radiation Therapy optimal for localized prostate cancer
5. Study examines adverse effects among different radiation therapies for prostate cancer
6. Chemo + Radiation Best for Bladder Cancer, Study Finds
7. Use of dedicated pediatric imaging departments for pediatric CT reduces radiation dose
8. APBI associated with more mastectomies, toxicities, complications, compared to traditional radiation
9. Cone beam CT proves better for visualizing some causes of hearing loss at half the radiation dose
10. Highly targeted irradiation as good as whole breast radiotherapy in early stage cancer
11. Novel biomarkers reveal evidence of radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Radiation for Childhood Cancer Might Raise Diabetes Risk
(Date:8/18/2017)... ... August 18, 2017 , ... ... asset protection assistance to communities in North-Central West Virginia, is embarking on a ... at-risk boys in the area. , The Chestnut Mountain Ranch (CMR) is a ...
(Date:8/18/2017)... ... 2017 , ... MLM Insurance Group, a Miami area provider ... is working to support the Take Stock In Children Foundation during a regional ... The Take Stock In Children Foundation (TSC) offers guidance and assistance to low ...
(Date:8/18/2017)... ... August 18, 2017 , ... Goss & Associates ... residential and commercial clients in the greater Houston region, is helping locally recognized ... the fight against cancer. , Founded by Tony and Amber Bender after losing ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... ... ... Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, Texas, has released a ... to the mother of the Savior whom the world calls “Mother Mary”. Yisrayl says when ... role of this historical woman. , “The world bows, kisses the feet of, cries ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... Mich. , Aug. 7, 2017 Diplomat Pharmacy, ... of Joel Saban as president, effective Aug. 7, ... Urick has decided to pursue other interests and will ... "During his tenure, Paul has served us in multiple leadership ... Specialty Pharmacy in Jun. 2015 and has provided decisive, strategic ...
(Date:8/7/2017)... 7, 2017  Endo International plc (NASDAQ: ... resolve virtually all known U.S. mesh product liability claims ... the known remaining U.S. claims at reasonable values. Under ... the fourth quarter of 2017 and continuing through the ... quarter 2017 results, the Company intends to increase its ...
(Date:8/4/2017)...  Agragen, LLC, a Cincinnati ... nutraceutical, and aquacultural feed sectors, announces a significant ... candidates, AGR131.  This drug is designed to trap ... of patients suffering from inflammatory conditions such as ... Biological pharmaceuticals currently ...
Breaking Medicine Technology: