Navigation Links
Radiation does not improve survival for rare, invasive bladder cancer
Date:6/2/2010

DETROIT In the largest study to date of a rare and deadly form of bladder cancer, researchers at Henry Ford Hospital in Detroit found radiation therapy may not improve a patient's chances for survival.

While overall survival for adenocarcinoma of the bladder was poor, the study revealed several factors that may improve a patient's prognosis, including being diagnosed at age 60 or younger, and having cystectomy, a procedure that either removes all or a portion of the bladder.

"While this malignancy afflicts just one to two percent of people diagnosed with bladder cancer, chances of surviving it for five years are grim only 18 percent in part because it is usually detected at an advanced stage," says study lead author Naveen Pokala, M.D., an urologist at Henry Ford Hospital.

"By the time the primary cancer is found, it may already have penetrated all four walls of the bladder and spread to adjacent organs and beyond, including the peritoneum, lymph nodes, and lungs."

The study will be presented June 2 at the 2010 American Urology Association's annual meeting in San Francisco.

In 2009, the National Cancer Institute estimated 70,980 new cases of bladder cancer were diagnosed in the U.S., while 14,330 died of the disease. According to the American Cancer Society, only about 1 percent of bladder cancers are adenocarcinomas. It invades the mucous cells in the bladder lining, and is the result of chronic irritation and inflammation. Nearly all adenocarcinomas of the bladder are invasive.

For their study, researchers at Henry Ford Hospital studied more than 850 patients with adenocarcinoma of the bladder, all selected from the National SEER database.

Of the study group, 96 patients had had a partial cystectomy; 164 had a total cystectomy; 375 had an endoscopy procedure; and 202 had an unspecified surgery. Among this group, some patients were treated with radiation therapy.

The population-based study had a mean age of 66.9 years among 514 males and 338 women; 707 were white, 94 African American, and 51 other races.

Race, the year of diagnosis, and radiation therapy did not affect survival.

Their overall survival rate was poor. The factors found in better prognoses were age 60 or younger; a well-differentiated, localized tumor in the dome (top) of the bladder, or the urachus, a vestigial cord that once connected the fetal bladder and contributed to development of the umbilical cord; and a total or partial cystectomy.


'/>"/>

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System
Source:Eurekalert

Related medicine news :

1. Radiation for Prostate Cancer May Boost Fracture Risk
2. Radiation Not Needed in Many Older Breast Cancer Patients
3. John Theurer Cancer Center offers breakthrough radiation measurement technology
4. Motorcycle Cancer Risk and ELF EMF Radiation Invasion of Gastrointestinal Melatonin
5. Concerns over radiation exposure may overshadow life-saving benefits of cardiac imaging tests
6. Simple reduction technique decreases radiation dose associated with CT scans of the head
7. Radiation Risks Nearly Double for Younger CT Scan Patients
8. Novel nanoparticles prevent radiation damage
9. Researchers successfully lower radiation dose associated with pediatric chest CT scans
10. Terminal cancer patients do not receive appropriate radiation therapy
11. Too Much Radiation? The FDA Wants to Know
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... SAN LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... with Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for ... mean is the 90-day elimination period, when the family pays for care, is often ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor ... on sciatica in a new episode of "Success Files," which is an award-winning ... innovation and investigates each subject in-depth with passion and integrity. , Sciatica occurs ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, ... post-acute health care, have expanded their existing home health joint venture through an ... has been operating a joint venture home health company with Asante, delivering clinically ...
(Date:10/12/2017)... ... ... On Saturday, October 21, the Health & Wellness Center at Florida Hospital ... for the American Heart Association Heart Walk. Teams of up to 10 people can ... their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on Saturday, ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... -- HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy ... team developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D ...
(Date:9/18/2017)... Mich. , Sept. 18, 2017  PMD Healthcare ... Specialty Pharmacy of Kalamazoo, Mich. , ... hub service that expedites and streamlines patient and provider ... PD 2.0, and wellness management services.  ... device used to measure lung function for a variety ...
(Date:9/13/2017)... 2017   OrthoAtlanta has been named the official ... Committee (AFHC) for the 2018 College Football Playoff (CFP) National ... Mercedes-Benz Stadium in Atlanta, Georgia . OrthoAtlanta ... In" campaign, participating in many activities leading up to, and ... ...
Breaking Medicine Technology: