Navigation Links
Radiation device in the breast reduces complications for early stage breast cancer patients
Date:4/23/2009

A new study shows that the SAVI applicator, a small, expandable device inserted inside the breast to deliver partial breast irradiation, carries a low infection risk, a potential complication of such devices. The research, led by radiation oncologists and surgeons at the Moores UCSD Cancer Center and Fort Myers, Florida-based 21st Century Oncology, also indicates that other complications such as seromas, pockets of fluid that build with the use of internal radiation devices are unlikely to occur.

That's good news for those women with early-stage breast cancer who opt to have such devices inserted for their radiation therapy after breast-sparing lumpectomy surgery, said Cate Yashar, MD, associate professor of radiation oncology at the UC San Diego School of Medicine and chief of breast and gynecological radiation services at the Moores UCSD Cancer Center. Their use is increasing, she added, noting that the Moores UCSD Cancer Center was one of the first medical facilities in the country to offer SAVI.

SAVI, which consists of flexible catheters through which radiation is given, provides customized radiation therapy and minimizes exposure to healthy tissue after a woman has undergone a lumpectomy to remove a cancerous tumor. Radiation specialists sometimes decide to give women internal radiation a process called brachytherapy with the goal of giving concentrated doses of radiation to areas of concern while avoiding healthy tissue.

In the study, researchers examined one-year follow-up data on 63 patients treated with the Food and Drug Administration-approved SAVI device. They found an infection rate that is less than half of the published rates associated with balloon brachytherapy methods, and rated overall cosmetic outcomes with SAVI as "excellent." The results will be presented at the American Society of Breast Surgeon's annual meeting in San Diego, April 24, 2009.

In addition, physicians were able to use the device's many catheters to customize the radiation dose based on the woman's needs, greatly minimizing radiation to the heart, lungs, ribs and skin, likely resulting in fewer complications, Yashar said. To date, there have been no recurrences or formation of persistent seromas.

"With a full year of follow-up, our research confirms previous findings that this device is safe and effective for radiation delivery, especially compared to other brachytherapy methods," said Yashar. "Without the ability to customize the dose, other devices can lead to complications, like persistent seroma and skin burns. This applicator was created to overcome these problems, and our research shows it has been successful."

Breast brachytherapy is a form of Accelerated Partial Breast Irradiation (APBI). Lasting just five days, APBI offers a shorter course of radiation compared to the six weeks required with traditional whole breast irradiation.

"SAVI has the most flexible dose modulation for single-entry APBI applicators and can sculpt the radiation dose to the size and shape of the tumor cavity and the patient's anatomy, even when only one to two millimeters from normal tissues," Yashar said.

Without the technical limitations of other methods such as balloon brachytherapy, SAVI substantially increases the number of women who qualify for the benefits of APBI, she noted.


'/>"/>

Contact: Steve Benowitz
sbenowitz@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert  

Related medicine news :

1. Majority of ordering physicians lack knowledge of radiation exposure risks from CT
2. Educating physicians about ventilation-perfusion scanning leads to reduced radiation exposure
3. Pediatric patient body shape may play a key role in decreasing radiation dose during CT scans
4. Excluding the lateral view in chest radiograph screenings decreases radiation exposure by 67 percent
5. Elekta Contract Provides MAGNET Cooperative Access to Leading Radiation Therapy Solutions
6. Worlds First Disposable Wireless RFID Sensor Detects Radiation Threats in Shipping Containers Using Modified Cell Phone Technology
7. Radiation Exposure Linked to Aggressive Thyroid Cancers
8. Acupuncture eases radiation-induced dry mouth in cancer patients
9. Experimental agents may prevent radiation-induced leukemia
10. Relief Is Available for Cancer Patients Suffering from Radiation Therapy-Related Nausea
11. Living With Radiation Conference Commemorating Chernobyl Nuclear Disaster Held at United Nations, Sponsored by New York Eye & Ear Infirmary
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Radiation device in the breast reduces complications for early stage breast cancer patients
(Date:7/21/2017)... ... July 21, 2017 , ... The Visiting ... the C. R. Bard Foundation, Inc. to support the music therapy ... service available through the nonprofit home care agency. Using evidence-based methods, professionally trained ...
(Date:7/21/2017)... ... July 21, 2017 , ... Sharon Kleyne is ... product of her research center at Bio-Logic Aqua Research® Water Life Science®, has ... greatest number of sufferers of blindness. “We think that Nature’s Tears® EyeMist® will ...
(Date:7/21/2017)... , ... July 21, 2017 , ... ... cruciate ligament (ACL) offer patients improved quality of life five years after injury, ... Medicine’s Annual Meeting in Toronto, Ontario, Canada. The study followed patients for ...
(Date:7/20/2017)... ... July 20, 2017 , ... ChenMed , a ... joined JenCare Senior Medical Center as Richmond Chief Medical Officer. Dr. ... Medicine, and Associate Chief Medical Officer of Ambulatory Services for the UVA Health System, ...
(Date:7/20/2017)... ... July 20, 2017 , ... ... in Houston, is pleased to announce their expansion to the Midwest with the ... directors Alysse Hollis and Ronald Bell, and of counsels, John Peck and Robert ...
Breaking Medicine News(10 mins):
(Date:7/21/2017)... -- Did you know that PhRMA member companies invested $65.5 billion ... on brand medicines, generics and the supply chain account for 14 ... half of this (7 percent)? Or that the United ... capital investments in high-growth biopharmaceutical startups? ... The biopharmaceutical industry ...
(Date:7/15/2017)... 15, 2017 Enterin Inc., a Philadelphia ... disease (PD), today announced the completion of a $12.7 million ... Ventures III, as well as the participation of existing investors. ... to have the support of New Ventures III and our ... validation of the potential of our platform technology to transform ...
(Date:7/13/2017)... -- RK Logistics Group, Inc. was awarded California ... Fremont, CA headquarters facility where it provides ... San Jose for hi-tech, pharmaceutical and biomedical ... with its Fremont Innovation District, is excited to strategically partner ... to the hundreds of biotech, pharma and biomed companies throughout ...
Breaking Medicine Technology: