Navigation Links
Radiation beneficial for older breast cancer patients
Date:4/11/2008

A breast cancer patients age alone should not determine whether or not she receives standard breast-conservation treatments, including a lumpectomy and radiation therapy; however, if additional health problems (comorbidities) are present, treatments should be individualized based on age and the type of comorbidities, according to a study in the April 1 edition of the International Journal for Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.

The occurrence of breast cancer in women increases as women age. According to the National Cancer Institutes SEER Cancer Statistics Review, women between the ages of 75 and 79 have the highest incidence of breast cancer diagnoses at 497 cases per 100,000 people. Along with cancer, most women in this age group are dealing with additional health problems. According to a 1999 womens health and aging study in the Journal of Clinical Epidemiology, the majority of older patients diagnosed with cancer have at least one other medical condition and more than half of patients with cancer over the age of 65 have three or more associated medical conditions.

This study, conducted by the departments of Radiation Oncology, Biostatistics and Epidemiology, and Medicine, Division of Geriatrics, at the University of Pennsylvania School Of Medicine in Philadelphia, sought to determine the impact of these additional medical problems on breast cancer patients who receive the same standard treatments as patients with no additional medical problems and if old age is a reason to deny some standard treatments.

Most randomized trials that compare outcomes of breast-conserving surgery with and without radiation consistently show more positive outcomes when radiation is used; however, most of the trials exclude women older than 70 years old so there is not a lot of data on the impact of radiation on older women.

Between 1979 and 2002, 238 women, 70 years old and older, with Stage I or II invasive carcinoma of the breast received breast-conservation therapy and their outcomes were compared by age groups and comorbidities. Most of the patients studied had mild comorbidities.

The researchers found that the number of deaths from breast cancer among the patients studied was similar to the number seen among all age groups of patients without additional medical problems. The researchers also found that the majority of elderly women with early-stage breast cancers and mild comorbidities actually benefited from the use of radiation and had minimal side effects.

The overall survival rates for the patients in the five- and 10-year follow-up periods were 80 percent and 50 percent, respectively; however, more deaths during the 10-year period were caused by intercurrent diseases than breast cancer.

Doctors need to understand that comorbidities should be the determining factor in deciding an older patients course of treatment, not age, said Eleanor Harris, M.D., clinical director of radiation oncology at the Moffitt Cancer Center in Tampa, Fla. There is a sense in the field that elderly women need less treatment than younger women, but we should not be under treating women simply because they have passed the age of 70.


'/>"/>

Contact: Nicole Napoli
nicolen@astro.org
American Society for Therapeutic Radiology and Oncology
Source:Eurekalert

Related medicine news :

1. Informational handout key to giving parents a better understanding of CT radiation risks
2. Prophylactic cranial irradiation in small cell lung cancer significantly increases survival
3. Different method of evaluating the urinary tract system reduces radiation dose
4. Radiation and drug combo helps boost efficacy of lung cancer treatment
5. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
6. Radiation therapy technique reduces length of prostate cancer treatment
7. Radiation therapy technique reduces length of prostate cancer treatment
8. Jefferson radiation oncologists use real-time system to plant seeds against cancer
9. Radiation Therapy Services Acquires North Carolina Facility
10. NASA, NSBRI Select 17 Proposals in Space Radiation Research
11. Breast Cancer Radiation Wont Hurt Immune Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2017)... , ... April 29, 2017 , ... ... Company to the list of fine retailers selling biodegradable, hanging flushable wipes dispensers ... a large supermarket chain headquartered in San Antonio, Texas, operates more than 350 ...
(Date:4/28/2017)... ... April 28, 2017 , ... Accreditation Commission for Health ... Association of America (HCAOA). This agreement allows HCAOA members to receive special pricing ... discounts on Accreditation University (AU) educational resources that help prepare HCAOA members for ...
(Date:4/28/2017)... ... 2017 , ... Getting enough sleep affects much more than energy – it also has mental ... sleep can compromise motor reaction time, which can increase the risk of having a car ... following tips from the NSF to help you sleep better and feel better:, ...
(Date:4/28/2017)... Manhattan New york (PRWEB) , ... April 28, ... ... is pleased to announce that Aditya Patel M.D. has joined the revolutionary endoscopic ... fellowship training and board certification in Interventional Pain Medicine. The patented, revolutionary eDiscSculpt ...
(Date:4/28/2017)... ... April 28, 2017 , ... People are starting to accept that hearing aids ... doesn’t have the stigma it had when great-grandpa wore his hearing aids years ago,” ... a NALA North American Speaker Series (NASS) segment. “He probably wore an ...
Breaking Medicine News(10 mins):
(Date:4/26/2017)... 2017 Phoenix Marketing Solutions ( Phoenix ... its mission of transforming science into clinical practice. During a ... Phoenix,s innovative approach supports the life sciences industry ... advances in science and medicine — which ultimately improves lives. ... in 2002 by Tracy Doyle and Angela ...
(Date:4/24/2017)... , April 24, 2017 SW Safety Solutions, ... and comfort, announces the release of the latest advancement ... most recent example of leading edge nitrile glove technology ... for 200% more tactile grip on wet and oily ... durability. With TracTek and a suite of other advanced ...
(Date:4/21/2017)... PHILADELPHIA , April 21, 2017 Halo ... high throughput biopharmaceutical particle analysis system called the Horizon ... on May 1st. The new system analyzes sub visible ... first time rapid particle screening as early as candidate ... working with leading biopharma contract research organization Elion ...
Breaking Medicine Technology: