Navigation Links
Radiation at time of lumpectomy may offer faster, more precise treatment for breast cancer patients

CHICAGO- Northwestern Medicine physicians are currently utilizing a new treatment option for breast cancer that allows women to receive a full dose of radiation therapy during breast conserving surgery. Traditionally, women who opt to have a lumpectomy must first have surgery then undergo approximately six weeks of radiation. This schedule can be challenging for women who have busy schedules or do not have access to a center offering radiation therapy. In some cases, the demanding schedule causes women to not comply with the recommended course of treatment, increasing their risk for cancer recurrence. Intraoperative radiation therapy combines lumpectomy and the full course of radiation during a two and half hour operation.

"With this technique, the radiation oncologist will be in the operating room administering radiation to the tumor bed immediately following the surgeon's removal of the tumor," said William Small, Jr., MD, vice chairman radiation oncology at Northwestern Memorial Hospital and professor of radiation oncology at Northwestern University Feinberg School of Medicine. "Instead of waiting a month to start the radiation therapy, it will take place immediately. A patient will wake up from surgery and have received the full amount of radiation therapy that is typically administered over six weeks."

Currently, a breast cancer patient first sees a surgeon to remove the tumor and then is referred to a radiation oncologist for follow up radiotherapy. Intraoperative radiation therapy allows physicians to deliver radiotherapy at the time of surgery directly to the area where the cancer was removed. Using a system called IntraBeam, the radiation oncologist is now able to be in the operating room with the surgical oncologist, delivering the entire dose of radiation during surgery. A large international randomized trial confirmed that delivering radiation at the time of lumpectomy was as effective in preventing breast cancer recurrence as whole breast radiation therapy in selected patients (WBRT).

Not all patients who choose lumpectomy comply with the recommended follow up treatment because of factors including time, money, distance and access to a treatment facility. Neglecting follow up radiation after lumpectomy can increase the risk of cancer recurrence. Intraoperative radiation significantly cuts treatment time and allows women to complete radiation and surgery at the same time.

"By eliminating the geographic and time constraints of traditional radiotherapy, intraoperative radiation can make breast conservation surgery a realistic option for more women," said Kevin Bethke, MD, surgical oncologist at Northwestern Memorial and assistant professor of clinical surgery at the Feinberg School. "Active women with busy jobs can choose lumpectomy and comply with the recommended radiation therapy, but limit the impact the treatment has on their lives."

Along with offering an expedited treatment schedule, intraoperative radiation therapy also has the potential for better cosmetic outcomes, including less scarring, and fewer side effects compared to those associated with WBRT. Skin reactions, including redness, rashes, and irritation, as well as more severe complications including fatigue, swelling, tissue stiffness and scarring are sometimes associated with traditional radiation therapy.

While initial findings indicate single-dose radiation is as effective as WBRT in limiting recurrence of breast cancer in selected patients, it is not an option for every breast cancer diagnosis. Currently, only women with early stage breast cancer are considered as candidates for intraoperative radiation therapy.

"This isn't a replacement for traditional breast cancer treatment, but for the right candidate it may be an attractive alternative," said Small. "This has potential to expand access to radiation therapy allowing more women to comply with the recommended course of treatment. Hopefully, with a more concise and convenient treatment available, a broader group of women will have the option to choose breast conserving treatment options."

The physicians hope that by offering intraoperative radiation therapy, they can help their patients effectively treat their cancer, but also do so in a manner that minimizes its impact on their daily lives. "A cancer diagnosis can be extremely stressful for a patient, so it's important that treatment is not," said Bethke. "With this new option, we're giving women a way to treat their disease while continuing to live a normal, active life."


Contact: Megan McCann
Northwestern Memorial Hospital

Related medicine news :

1. New radiation treatment practice recommendations for thyroid disease
2. Soy increases radiations ability to kill lung cancer cells, study shows
3. Despite Radiation in Japan, Little Shift in Americans Views on Nuke Power: Poll
4. Levels of Radiation in Wash. State Milk No Threat to Health: FDA
5. Benefits of Radiation Therapy Outweigh Risks of a Second Cancer: Study
6. LSUHSC research finds protein that protects cancer cells from chemo and radiation therapy
7. Statins make radiation more effective at curing prostate cancer
8. Trace Amounts of Radiation Reach California; No Health Risk, Experts Say
9. Radiation risks to health: A joint statement from leading scientific experts
10. Radiation From Japans Nuke Disaster Unlikely to Threaten U.S., Experts Say
11. U.S. Unprepared for Major Radiation Emergency: Survey
Post Your Comments:
(Date:6/24/2016)... ... ... A recent article published June 14 on E Online details ... to state that individuals are now more comfortable seeking to undergo not only the ... and cheek reduction. The Los Angeles area medical group, Beverly Hills Physicians (BHP) notes ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell ... pain and the benefits of holistic treatments, Serenity Recovery Center of Marne, ... Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Conference and Scientific Sessions in Dallas that it will receive two significant new ... the grants came as PHA marked its 25th anniversary by recognizing patients, medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, an ... Dr. Cheng has extensive experience with all areas of orthodontics, including robotic Suresmile ... orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can ...
(Date:6/24/2016)... ... ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for ... $12 an hour by 2020 and then adjusting it yearly to increase at the same ... wage, assure the wage floor does not erode again, and make future increases more predictable. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... a startling report released today, National Safety Council research ... proven plan to eliminate prescription opioid overdoses. Prescription Nation ... tackling the worst drug crisis in recorded U.S. history, assigned a ... , New Mexico , Tennessee ... failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)...  Guerbet announced today that it has been named ... . One of 12 suppliers to receive ... support of Premier members through exceptional local customer service ... to lower costs. ... outstanding customer service from Premier," says Massimo Carrara ...
Breaking Medicine Technology: