Navigation Links
Radiation Not Needed in Many Older Breast Cancer Patients
Date:5/21/2010

No added benefit over surgery plus tamoxifen alone in those 70-plus with early stage disease, study finds

FRIDAY, May 21 (HealthDay News) -- A new study provides more support for the idea of allowing women aged 70 and older with early stage breast cancer to avoid radiation treatment if they have undergone a lumpectomy and treatment with the drug tamoxifen.

"The standard of care for women 70 and older with very small tumors that are estrogen-positive and node-negative -- the largest group of breast cancer patients in this age group -- had been lumpectomy and radiation," study lead author Dr. Kevin Hughes, co-director of the Avon Comprehensive Breast Evaluation Center at Massachusetts General Hospital in Boston, said in a news release.

"Earlier reports of this study with shorter median follow-up have shown the risk of recurrence without radiation to be only marginally worse than with radiation, but there was concern that longer follow-up would show a blossoming of recurrences," he said. "This study confirms that for older women with early stage breast cancer, lumpectomy without radiation is a viable alternative, and tamoxifen may replace the need for radiation."

It has been standard for younger women with early stage breast cancer to receive radiation therapy after a lumpectomy.

The researchers reached their conclusions after randomly assigning 636 women with early stage breast cancer -- all 70 or older -- to receive tamoxifen (319 patients), or tamoxifen plus radiation (317 patients).

After a median follow-up of more than 10 years, the researchers found that the risk of recurrence was lower among those who received both treatments (2 percent) compared with those who received the drug alone (8 percent). But the two groups didn't differ significantly in terms of overall survival and risk of dying from breast cancer.

The findings were released May 20 and the study is to be presented at the annual meeting of the American Society of Clinical Oncology, June 4 to 8 in Chicago.

More information

For more about breast cancer, visit BreastCancer.org .



-- Randy Dotinga



SOURCE: American Society of Clinical Oncology, news release, May 20, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. John Theurer Cancer Center offers breakthrough radiation measurement technology
2. Motorcycle Cancer Risk and ELF EMF Radiation Invasion of Gastrointestinal Melatonin
3. Concerns over radiation exposure may overshadow life-saving benefits of cardiac imaging tests
4. Simple reduction technique decreases radiation dose associated with CT scans of the head
5. Radiation Risks Nearly Double for Younger CT Scan Patients
6. Novel nanoparticles prevent radiation damage
7. Researchers successfully lower radiation dose associated with pediatric chest CT scans
8. Terminal cancer patients do not receive appropriate radiation therapy
9. Too Much Radiation? The FDA Wants to Know
10. Radiation after mastectomy underused, U-M study finds
11. New York Medical Malpractice Attorney Recommends Cancer Patients Take Precautionary Steps Before Undergoing Radiation Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... ... 23, 2017 , ... The physicians of KSF Orthopaedic Center PA are proud ... new location is located at 2255 E. Mossy Oaks Rd., Suite 440, Spring, Texas ... will provide patients living in the north Houston area (The Woodlands, Conroe, Magnolia, Kingwood, ...
(Date:3/23/2017)... ... 23, 2017 , ... The IoT (Internet of Things) is revolutionizing the way ... impact on businesses and individual consumers alike. Laboratories can maximize their profit margin ... anywhere from $4 trillion to $11 trillion dollars by the year 2025. McKinsey expects ...
(Date:3/23/2017)... ... March 23, 2017 , ... March is National Kidney Month – the ... it comes to maintaining good health. Every day, two kidneys filter about 120 to ... drop of your blood, eliminating waste, regulating fluid levels and blood pressure, supporting bone ...
(Date:3/23/2017)... ... March 23, 2017 , ... The ... organized by HMP Communications Holdings, LLC, today announced that RestorixHealth® has ... network of wound centers interested in becoming Certified Wound Specialist Physicians (CWSP®). ...
(Date:3/23/2017)... ... March 23, 2017 , ... After raising more than $1.135 million ... most-funded travel pillow in crowdfunding history, has established a U.S. Headquarters in ... travel innovation to Americans. , “We’re excited to be operating on U.S. shores, where ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... March 23, 2017 CENTRO DE IMAGEM DIAGNOSTICOS ... paragraph 4 of Law 6,404/76 and Instruction 358/02 of ... its shareholders and the market in general that it ... Centro de Diagnosticos por Imagem Ltda. (" CDI "), ... in RADIOLOGISTAS ASSOCIADOS LTDA. (" Partnership " and " ...
(Date:3/23/2017)... , March 23, 2017  The goal ... system to identify and track prescription drugs as they ... , in response to requirements from US FDA to ... of potentially dangerous medicines. Blockchain startup ... cryptographic identity chips and blockchain technology and recently raised ...
(Date:3/23/2017)... , March 23, 2017  Cornerstone Pharmaceuticals, ... a major milestone today.  Following successful End-of-Phase ... U.S. Food and Drug Administration (FDA), the ... and regulatory path forward to conduct pivotal ... patients with acute myeloid leukemia (AML) and ...
Breaking Medicine Technology: