Navigation Links
Radiation Not Needed in Many Older Breast Cancer Patients
Date:5/21/2010

No added benefit over surgery plus tamoxifen alone in those 70-plus with early stage disease, study finds

FRIDAY, May 21 (HealthDay News) -- A new study provides more support for the idea of allowing women aged 70 and older with early stage breast cancer to avoid radiation treatment if they have undergone a lumpectomy and treatment with the drug tamoxifen.

"The standard of care for women 70 and older with very small tumors that are estrogen-positive and node-negative -- the largest group of breast cancer patients in this age group -- had been lumpectomy and radiation," study lead author Dr. Kevin Hughes, co-director of the Avon Comprehensive Breast Evaluation Center at Massachusetts General Hospital in Boston, said in a news release.

"Earlier reports of this study with shorter median follow-up have shown the risk of recurrence without radiation to be only marginally worse than with radiation, but there was concern that longer follow-up would show a blossoming of recurrences," he said. "This study confirms that for older women with early stage breast cancer, lumpectomy without radiation is a viable alternative, and tamoxifen may replace the need for radiation."

It has been standard for younger women with early stage breast cancer to receive radiation therapy after a lumpectomy.

The researchers reached their conclusions after randomly assigning 636 women with early stage breast cancer -- all 70 or older -- to receive tamoxifen (319 patients), or tamoxifen plus radiation (317 patients).

After a median follow-up of more than 10 years, the researchers found that the risk of recurrence was lower among those who received both treatments (2 percent) compared with those who received the drug alone (8 percent). But the two groups didn't differ significantly in terms of overall survival and risk of dying from breast cancer.

The findings were released May 20 and the study is to be presented at the annual meeting of the American Society of Clinical Oncology, June 4 to 8 in Chicago.

More information

For more about breast cancer, visit BreastCancer.org .



-- Randy Dotinga



SOURCE: American Society of Clinical Oncology, news release, May 20, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. John Theurer Cancer Center offers breakthrough radiation measurement technology
2. Motorcycle Cancer Risk and ELF EMF Radiation Invasion of Gastrointestinal Melatonin
3. Concerns over radiation exposure may overshadow life-saving benefits of cardiac imaging tests
4. Simple reduction technique decreases radiation dose associated with CT scans of the head
5. Radiation Risks Nearly Double for Younger CT Scan Patients
6. Novel nanoparticles prevent radiation damage
7. Researchers successfully lower radiation dose associated with pediatric chest CT scans
8. Terminal cancer patients do not receive appropriate radiation therapy
9. Too Much Radiation? The FDA Wants to Know
10. Radiation after mastectomy underused, U-M study finds
11. New York Medical Malpractice Attorney Recommends Cancer Patients Take Precautionary Steps Before Undergoing Radiation Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June 14 ... The article goes on to state that individuals are now more comfortable seeking to ... operations such as calf and cheek reduction. The Los Angeles area medical group, Beverly ...
(Date:6/24/2016)... ... 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida ... their peers for this recognition are considered among the top 2 percent of lawyers ... as members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark ...
(Date:6/24/2016)... ... 24, 2016 , ... EB Medicine presented its first-ever “Issue ... conference in Ponte Vedra Beach, FL. The awards honor the outstanding work of ... and Pediatric Emergency Medicine Practice. , “With this award, we recognize the ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)...   Bay Area Lyme Foundation , collaborating ... for Tick Borne Illness , Harvard Medical School ... Medicine, University of California, Berkeley, and the Veterans ... finalists of Lyme Innovation , the first ... scientists, clinicians, researchers, entrepreneurs, and investors from several ...
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
Breaking Medicine Technology: