Navigation Links
Racial difference in blood clotting warrants a closer look at heart attack medications
Date:11/10/2013

r if these findings relate to drugs that are currently prescribed or to those currently in development.

Further molecular studies identified a novel gene called PCTP that mediated platelet activation through PAR4. PCTP was expressed at higher levels in platelets from blacks and appears to be a major contributor to the racial difference in blood clotting. Furthermore, a microRNA was identified that silenced the expression of PCTP; this microRNA was expressed at higher levels in platelets from whites than blacks and may contribute to the lower levels of thrombin activation through the PAR4 receptor in whites.

In fact, the researchers found many silencing microRNAs were more actively expressed in whites than in blacks, at least in platelets, suggesting that other aspects of platelet biology may be regulated differently depending on race. Uncovering the genes that these microRNAs suppress could help researchers hone in on individual differences in platelet function, and eventually how these differences contribute to disease and response to anti-clotting treatments.

"In this age where there is such a focus on delivering personalized medicine, we should embrace these differences to try to give our patients better care," says Dr. Bray.


'/>"/>

Contact: Edyta Zielinska
edyta.zielinska@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UC Irvine study finds racial, economic disparities in ovarian cancer care, survival
2. Racial make-up of community impacts obesity risk
3. Racial Gap in Kids Dental Care Vanishing: Study
4. Multiracial youths show similar vulnerability to peer pressure as whites
5. New CDC study on racial disparities in infant mortality published in Journal of Womens Health
6. Black gay men worldwide 15 times more likely to have HIV and racial disparity
7. Racial differences in diabetes diagnostic thresholds
8. Vanderbilt-led study reveals racial disparities in prostate cancer care
9. CT depicts racial differences in coronary artery disease
10. Are there racial disparities in osteoporosis screening and treatment?
11. Racial Disparities Still Seen in Use of Breast Cancer Treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... ARBOR, Mich. Nearly 7 in 10 Americans ... a new national survey by researchers at the University ... with children under the age of 18 at home, ... more likely than other adults to support universal coverage ... appear in the Journal of the American Medical ...
(Date:4/22/2014)... patients diagnosed with non-small cell lung cancer are 70 ... percentage, these elderly patients are not well represented in ... made it difficult to reach evidence based clinical recommendations. ... Task Force and Lung Cancer Group along with the ... opinion on managing treatment for elderly patients with non-small ...
(Date:4/22/2014)... parallel with modern man ( Homo sapiens ), there were ... side by side, such as Neanderthals and the recently discovered ... survived. What was it in our genetic makeup that gave ... known about our unique genetic makeup as distinguished from our ... we are the only species among them ,to survive. Even ...
(Date:4/22/2014)... DC -- When mothers are exposed to trauma, illness, ... a single molecular trigger in brain cells that can ... stress disorder and some forms of autism. , Until ... have impacted the cells of a developing brain. Past ... herself to alcohol or drug abuse or she experiences ...
(Date:4/22/2014)... may be influenced by low exposure to testosterone in ... revealed how men,s testosterone levels may be determined before ... less of the hormone than others is important because ... of the hormone have been linked to obesity, diabetes ... cells responsible for producing testosterone in adults known ...
Breaking Medicine News(10 mins):Health News:More than two-thirds of Americans support mandated coverage of birth control in health plans 2Health News:EORTC and SIOG update expert opinion on management of elderly patients with NSCLC 2Health News:What gave us the advantage over extinct types of humans? 2Health News:Life stressors trigger neurological disorders, researchers find 2
... designed to treat chronic inflammatory conditions and leukemia resulted ... men involved in the trail becoming seriously ill. ... drug reaction. ,Dr. Ganesh Suntharalingam and colleagues ... immune system overreaction, known as a cytokine storm, was ...
... Clinton and Microsoft boss Bill Gates said inadequate access to ... combating the AIDS epidemic, in addresses to the largest ever ... continue to fight the stigma and stop people from being ... ,Both Clinton and Gates have donated billions of dollars ...
... be programmed to encourage fidgeting and other restless behaviors that ... research published by The American Physiological Society. ,The ... lean are more sensitive to a chemical produced in the ... such as fidgeting and other unconscious movements. Compared to rats ...
... good alternative for identifying risks for kidney disease, cardiovascular disease, ... a researcher at the San Francisco VA Medical Center, has ... incapable of picking up chronic health risks among the elderly., ... at risk for kidney disease, this is an important message: ...
... Neurosciences Institute in Rockville have claimed that the discovery ... patients// with Alzheimer's disease, could be developed as a ... ,The researchers explained that not only would be quick ... test for diagnosing Alzheimer's disease, which as of now ...
... Eighth International Conference on Mercury as a Global Pollutant, ... noted that Mercury pollution// can threaten the health of ... remote corners of the planet, but reducing mercury use ... declaration essentially says that mercury pollution is a problem ...
Cached Medicine News:Health News:Experimental Drug Causes Cytokine Storm 2Health News:Biological Basis Behind a Couch Potato 2Health News:Biological Basis Behind a Couch Potato 3Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 2Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 3Health News:Scientists Claim Developing A New Skin Test For The Early Detection Of Alzheimer’ 2Health News:Dangers Of Mercury 2
(Date:1/14/2014)... 2014 The Brandeis Medical Center, led by Dr. Emmanuel ... and affordable laser tattoo removal experience with the advanced Astanza Duality ... providing high quality cosmetic services with cutting edge medical technology and ... Southern California has seen a dramatic increase in the ...
(Date:1/14/2014)... Emergency Critical Care, a LifeCentre partner practice, located at 165 Fort ... first in Loudoun County to receive a ... M. Barnes , Medical Director, is a well-seasoned veterinarian of more ... , are avid scuba divers. "As altitude skiers and hikers, we ...
(Date:1/14/2014)... , Jan. 14, 2014   Oligomerix, Inc. , a ... therapeutics for Alzheimer,s disease (AD) and related neurodegenerative disorders, ... Valhalla, NY as of January ... space at New York Medical College. Oligomerix, ...
Breaking Medicine Technology:Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... Sevocity, a division of Conceptual MindWorks, Inc. (CMI), today ... as a preferred electronic health record (EHR) vendor with ... leading true Internet or cloud-based EHR. This enables Sevocity ... health record system with low start-up cost and affordable ...
... STAMFORD, Conn., July 20, 2011 A new online ... healthcare professionals, law enforcement, and community organizations combat the ... Purdue Pharma L.P . has developed RxSafetyMatters.org ... company and organizations with which it is partnering to ...
Cached Medicine Technology:Sevocity® Named Preferred EHR Vendor by CITIA-SC, South Carolina's Health IT Regional Extension Center (REC) 2New Online Resource to Help Combat Abuse of Prescription Medications Launched by Purdue Pharma L.P. 2New Online Resource to Help Combat Abuse of Prescription Medications Launched by Purdue Pharma L.P. 3
... System is designed to help physicians provide ... leg. Endovenous laser therapy is a patient-friendly ... of varicose veins., In endovenous laser therapy, ... the varicosed vein, generally through a small ...
ELVeS is a new minimally-invasive laser treatment for patients with superficial vein reflux of the greater saphenous vein. The ELVeS laser treatment offers your patients an effective out-patient alt...
Using proven 1064 nm technology for the treatment of deeper lesions, the Lumenis One Multi-Spot Nd:YAG module provides versatility allowing targeted treatment of leg veins, vascular lesions, facial w...
... #1 physician choice in laser treatment, brings ... superficial vein reflux. EVLT is a minimally ... stripping that effectively and safely treats varicose ... occlude the vein. The procedure is easy ...
Medicine Products: