Navigation Links
Racial and ethnic differences in colorectal cancer emphasize importance of screening
Date:10/15/2007

Philadelphia, PA, October 15, 2007 New research presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology emphasizes the importance of colorectal cancer (CRC) screening among racial and ethnic minorities, who have a higher incidence of colorectal cancer compared to Caucasians. Two studies found more African-Americans had advanced polyps on the right side of the colon than Caucasians, while results from colonoscopy screenings of Latin Americans revealed similarly high risk findings to African-Americans.

African-Americans have a high overall incidence of colorectal cancer and a greater prevalence of proximal or right-sided polyps and cancerous lesions. The right side of the colon includes the cecum, ascending colon and proximal transverse colon and cannot be reached by flexible sigmoidoscopy.

The reasons for higher incidence rates in African-Americans are unclear; however, dietary, nutritional factors, rates of physical inactivity, variability in screening rates, lower use of diagnostic testing, and increasing smoking rates have been most commonly implicated.

Dr. Roy D. Yen and his colleagues from the University at Buffalo and the VA Western New York analyzed the results of 587 colonoscopies (78 African-Americans, 502 Caucasians) performed at their institution in 2004. The number and location of polyps and presence of advanced lesions between the two cohorts were examined. They found significantly more African-American patients (14 percent) had advanced right-sided, or proximal, polyps compared to Caucasian patients (5.4 percent). Researchers also found more black patients had advanced polyps, proximal polyps and proximal colon cancers than whites.

Based on the results of this study, Flexible sigmoidsocopy may be inadequate for colorectal cancer screening in this population. African Americans should undergo colonoscopy with particular attention for proximal lesions, however larger prospective studies are needed to confirm these findings, said Dr. Yen.

Colonoscopy Among Latin Americans Reveals Similar Incidence of High Risk Findings to African-Americans

In a retrospective analysis conducted at The University Hospital and the New Jersey Medical School in Newark, NJ, Dr. Stanley H. Weiss, Dr. Mark J. Sterling, and their research team reviewed screening colonoscopies performed in 2005 and 2006. They found Latin Americans had a higher than expected incidence of polyps, pathologically significant lesions, and significant right-sided lesions, similar to previously reported findings in African-American patients.

Of the 756 screening colonoscopies, 287 (38 percent) were in Latin Americans and 331 (44 percent) were in African-Americans. Forty-eight percent of Latin Americans had pathologically significant lesions, compared to forty-six percent among African-Americans. The percentage of pathologically significant right-sided polyps was similar in Latin Americans (57 percent) and African-Americans (62 percent). However, researchers found that African-Americans were significantly more likely to have a large polyp (>1 cm) than Latin Americans and were more likely to have a large right-sided polyp.

According to study leader Dr. Stanley H. Weiss, Because right-sided lesions are detectable with colonoscopy, which examines the whole colon, but not by flexible sigmoidoscopy, these findings have important implications for appropriate screening for colon cancer in Latin Americans.


'/>"/>

Contact: Rosanne Riesenman
mediaonly@acg.gi.org
301-263-9000
American College of Gastroenterology
Source:Eurekalert

Related medicine news :

1. Death Wishes Influenced By Ethnicity and Racial Background
2. Racial Identity Dictates What We See Or Rather Whom We See
3. Racial disparities in cancer patients in U.S.
4. Racial differences show difference in blood sugar control too!!
5. Medicare Marked by Widespread Racial disparities
6. Racial Gap in Floridas Infant Mortality Rates Increasing
7. Risk of Birth Complications Varies Between Racial Groups
8. More Evidence of Racial Discrimination in the NHS
9. Social Factors Not Genetics Drive Racial Disparities in Colorectal Cancer Survival
10. Racial Discrimination Takes The Nobility Out Of Doctoring
11. Ethnic discrepancy in ovarian cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping ... fitness app. The fitness app plans to fix the two major problems leading the fitness ... size fits all type program , They don’t eliminate all the reasons people ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American Institutes ... Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , ... advance care planning, healthcare costs and patient and family engagement. , AIR researchers ...
(Date:6/25/2016)... Miami, FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton ... Plant City Observer , brings up a new, often overlooked aspect of head lice: ... The closing for fumigation is not a common occurrence, but a necessary one in the ...
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding emergency ... its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. Ogunleye ... M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. Ogunleye ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... June 24, 2016 The Academy of Managed ... recommendations that would allow biopharmaceutical companies to more ... that make formulary and coverage decisions, a move that ... new medicines. The recommendations address restrictions in ... on the drug label, a prohibition that hinders decision ...
(Date:6/24/2016)... According to a new market ... Needles, Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, ... of Purchase (Retail, Non-Retail) - Trends & Global Forecasts ... market for the forecast period of 2016 to 2021. ... by 2021 from USD 1.65 Billion in 2016, growing ...
Breaking Medicine Technology: