Navigation Links
Race, Weight May Influence Success of Prostate Surgery

Among diabetic men undergoing prostatectomy, obese whites have worse outcomes, study finds

FRIDAY, Jan. 15 (HealthDay News) -- Race and obesity may affect the outcome of men with diabetes who have prostate cancer surgery, a new U.S. study reveals.

"We found that diabetes was significantly associated with more aggressive disease in obese white men and less aggressive disease for all other subsets of men in our study," Dr. Stephen Freedland, an associate professor of urology and pathology at the Duke Prostate Center at Duke University, said in a Duke news release.

Freedland and colleagues examined the medical records of 1,262 prostate cancer patients who had undergone radical prostatectomy -- surgery to remove the prostate gland and some tissue surrounding it.

The researchers found an association between diabetes and an increased risk of cancer recurrence and a trend toward more aggressive recurrence in obese white men. In all other groups of men, diabetes was associated with lower recurrence risk.

"We really don't know what mechanisms might be in place that could account for this relationship," Freedland said. "But consider this: diabetes is associated with low levels of insulin and testosterone, an inhospitable environment for tumor growth. This is compounded in obese white men who also have lower insulin-like growth factor levels. The thinking is that if a tumor is powerful enough to grow in such a hostile environment, then it's probably a pretty aggressive one."

The study was published in the January issue of Cancer Epidemiology, Biomarkers & Prevention.

More information

The American Cancer Society has more about prostate cancer.

-- Robert Preidt

SOURCE: Duke Medicine, news release, Jan. 11, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study shows insurance status, not race, linked to complications in patients with acute appendicitis
2. Race, Gender Affect Laryngeal Cancer Survival
3. Race, insurance status affect access to transplantation and kidney disease treatment
4. Groundbreaking Town Hall Meeting to Explore Why Race, Income and Geography Can Predict Health
5. Womens Awareness of Cancer Risk Linked to Race, Ethnicity
6. Perceptions and experiences of homeless youth vary by race, UCSF study shows
7. Study of neighborhoods points to modifiable factors, not race, in cancer disparities
8. Shared Race, Social Group Seem to Help People Relate
9. Race, Insurance May Affect Testing of Kids in ER
10. Race, obesity affect outcomes among diabetics following prostatectomy
11. Does race, income predict prostate cancer outcome?
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... “While riding the bus, I ... Bronx, N.Y. “I thought there had to be a convenient and comfortable way to ... The PROTECTOR enables disabled individuals to safely travel during cold or inclement weather. In ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... ... Association (PHA) announces the nation’s Periwinkle Pioneers, individuals and groups responsible for advancing ... this disease. The Periwinkle Pioneers, nominated by the public, will receive special recognition ...
(Date:11/25/2015)... ... November 25, 2015 , ... An unlikely ... resulting in a way for homeless people to have a more dignified and ... new initiative whereby they are repurposing plastic bags into sleeping mats for the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Since ... providing comprehensive solutions involving adult stem cell therapies to patients with chronic degenerative ... “Regenestem” name as a Registered Trademark (RTM). , Organizations are required to hold ...
(Date:11/24/2015)... (PRWEB) , ... November 25, 2015 , ... ... and monitoring. Their Care Plan software creates an agreement between the practice ... care plan, including financial, scheduling, monitoring, notification, and projections. Click here ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... and BERN, Switzerland , November ... ARTORG Center for Biomedical Engineering Research of the University ... Division of Endocrinology, Diabetes and Clinical Nutrition of the ... start of an exclusive collaboration to develop a novel ... for the personalised delivery of insulin for diabetic patients ...
(Date:11/24/2015)... FLINT, Mich. , Nov. 24, 2015 Diplomat ... , Senior Vice President of Clinical Services, Education and Human ... (AIS) online webinar, "Oral Oncology Drugs: Health Plan Strategies for ... co-presenting with Beckie Fenrick , a consultant with the ... The webinar will ...
(Date:11/24/2015)... 24, 2015 iRhythm Technologies, Inc. , a leading ... announced that it will participate in the 27th Annual Piper Jaffray ... New York, NY . Kevin King , Chief ... 1, 2015 at 8:50am ET. --> ... . --> . --> iRhythm is ...
Breaking Medicine Technology: