Navigation Links
Race, Weight May Influence Success of Prostate Surgery

Among diabetic men undergoing prostatectomy, obese whites have worse outcomes, study finds

FRIDAY, Jan. 15 (HealthDay News) -- Race and obesity may affect the outcome of men with diabetes who have prostate cancer surgery, a new U.S. study reveals.

"We found that diabetes was significantly associated with more aggressive disease in obese white men and less aggressive disease for all other subsets of men in our study," Dr. Stephen Freedland, an associate professor of urology and pathology at the Duke Prostate Center at Duke University, said in a Duke news release.

Freedland and colleagues examined the medical records of 1,262 prostate cancer patients who had undergone radical prostatectomy -- surgery to remove the prostate gland and some tissue surrounding it.

The researchers found an association between diabetes and an increased risk of cancer recurrence and a trend toward more aggressive recurrence in obese white men. In all other groups of men, diabetes was associated with lower recurrence risk.

"We really don't know what mechanisms might be in place that could account for this relationship," Freedland said. "But consider this: diabetes is associated with low levels of insulin and testosterone, an inhospitable environment for tumor growth. This is compounded in obese white men who also have lower insulin-like growth factor levels. The thinking is that if a tumor is powerful enough to grow in such a hostile environment, then it's probably a pretty aggressive one."

The study was published in the January issue of Cancer Epidemiology, Biomarkers & Prevention.

More information

The American Cancer Society has more about prostate cancer.

-- Robert Preidt

SOURCE: Duke Medicine, news release, Jan. 11, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study shows insurance status, not race, linked to complications in patients with acute appendicitis
2. Race, Gender Affect Laryngeal Cancer Survival
3. Race, insurance status affect access to transplantation and kidney disease treatment
4. Groundbreaking Town Hall Meeting to Explore Why Race, Income and Geography Can Predict Health
5. Womens Awareness of Cancer Risk Linked to Race, Ethnicity
6. Perceptions and experiences of homeless youth vary by race, UCSF study shows
7. Study of neighborhoods points to modifiable factors, not race, in cancer disparities
8. Shared Race, Social Group Seem to Help People Relate
9. Race, Insurance May Affect Testing of Kids in ER
10. Race, obesity affect outcomes among diabetics following prostatectomy
11. Does race, income predict prostate cancer outcome?
Post Your Comments:
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... June 19, ... the dangers associated with chronic pain and the benefits of holistic treatments, Serenity ... who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a ...
(Date:6/24/2016)... Dallas, Texas (PRWEB) , ... June 24, 2016 ... ... 12th International Conference and Scientific Sessions in Dallas that it will receive two ... Announcement of the grants came as PHA marked its 25th anniversary by recognizing ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
(Date:6/24/2016)... ... ... Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair ... hour by 2020 and then adjusting it yearly to increase at the same rate as ... the wage floor does not erode again, and make future increases more predictable. , The ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
Breaking Medicine Technology: