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RXplore: New Regenstrief tool lets docs instantly track down drug reactions
Date:4/12/2010

INDIANAPOLIS It's not uncommon for individuals to take as many as a dozen different prescriptions, each with its own set of possible side effects. If a patient experiences one of the potential hundreds of different adverse reactions such as nausea, headaches, insomnia or heart palpitations, how does the physician quickly and accurately determine which drug is the culprit?

Jon D. Duke, M.D., a medical informatics fellow at the Regenstrief Institute and the Indiana University School of Medicine, has created an easy-to-use graphical tool called RXplore which expedites tracking down the cause of drug side-effects. His work is published in the April 2010 issue of the Journal of Biomedical Informatics.

Currently doctors depend on knowledge of drug reactions acquired from past experience or by reviewing published prescribing information either online or in print. When evaluating multiple drugs the physician must look up each medication one at a time, a time-consuming process made more difficult by the dense and complex text found in typical drug labels.

RXplore solves this problem in a novel manner allowing physicians and other health-care providers to retrieve adverse reaction data for multiple medications simultaneously with an intuitive visual representation. An evaluation study showed that physicians are able to retrieve accurate side-effect information 65 percent faster using Rxplore than when using traditional drug information resources.

"Patients on complex drug regimens are doubly disadvantaged. They are at increased risk for an adverse event, yet their physician may be less likely to perform a thorough review of their medications due to the lengthy time required," said Dr. Duke.

He notes that he came up with the concept of visualizing Food and Drug Administration drug data but soon found that labels were inconsistent in how adverse events were reported. The greatest challenge of this project, accordin
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Contact: Cindy Fox Aisen
caisen@iupui.edu
317-274-7722
Indiana University School of Medicine
Source:Eurekalert  

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RXplore: New Regenstrief tool lets docs instantly track down drug reactions
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