Navigation Links
RSNA: Contrast Agent Linked With Brain Abnormalities On MRI
Date:12/16/2013

Oak Brook, IL (PRWEB) December 16, 2013

For the first time, researchers have confirmed an association between a common magnetic resonance imaging (MRI) contrast agent and abnormalities on brain MRI, according to a new study published online in the journal Radiology. The new study raises the possibility that a toxic component of the contrast agent may remain in the body long after administration.

Brain MRI exams are often performed with a gadolinium-based contrast medium (Gd-CM). Gadolinium’s paramagnetic properties make it useful for MRI, but the toxicity of the gadolinium ion means it must be chemically bonded with non-metal ions so that it can be carried through the kidneys and out of the body before the ion is released in tissue. Gd-CM is considered safe in patients with normal kidney function.

However, in recent years, clinicians in Japan noticed that patients with a history of multiple administrations of Gd-CM showed areas of high intensity, or hyperintensity, on MRI in two brain regions: the dentate nucleus (DN) and globus pallidus (GP). The precise clinical ramifications of hyperintensity are not known, but hyperintensity in the DN has been associated with multiple sclerosis, while hyperintensity of the GP is linked with hepatic dysfunction and several diseases.

To learn more, the researchers compared unenhanced T1-weighted MR images (T1WI) of 19 patients who had undergone six or more contrast-enhanced brain scans with 16 patients who had received six or fewer unenhanced scans. The hyperintensity of both the DN and the GP correlated with the number of Gd-CM administrations.

“Hyperintensity in the DN and GP on unenhanced MRI may be a consequence of the number of previous Gd-CM administrations,” said lead author Tomonori Kanda, M.D., Ph.D., from Teikyo University School of Medicine in Tokyo and the Hyogo Ca
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. RSNA: Brain Chemical Ratios Help Predict Developmental Delays in Preterm Infants
2. RSNA: MR Spectroscopy Shows Differences in Brains of Preterm Infants
3. RSNA: Embolization Procedure Aids in Weight Loss
4. RSNA: Self-Referral Spurs Unnecessary MRI Exams for Patients
5. RSNA: Multicenter Trial Finds BI-RADS 3 Breast Lesions Have Low Cancer Rate
6. RSNA: Tomosynthesis Reduces Breast Cancer Screening Recall Rate
7. RSNA: Some Women With Abnormal Breast Lesions May Avoid Surgery
8. RSNA: Hospital Mammography Recall Rates Higher
9. RSNA: Fat in Organs and Blood May Increase Risk of Osteoporosis
10. RSNA: Exercise Benefits Patients with Type 2 Diabetes
11. RSNA: Atherosclerosis in Abdominal Aorta May Signal Future Heart Attack, Stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Pain Free Living a leader in the ... new Superior magnetic necklace using ion neodymium ... neodymium magnets for the fastest pain relief in a ... Magnetics brand for the fastest relief by using 5200 ... using Superior Magnetic Jewelry at fairs and festivals” explained ...
(Date:12/19/2014)... December 19, 2014 After a 13-year ... is again returning to the stage to entertain his ... for concert performances, and the successful tour has been ... announced. , Visit Ticketability.com for a ... Detroit shows at fair prices. , Music fans have ...
(Date:12/19/2014)... THURSDAY, Dec. 18, 2014 (HealthDay News) -- Being in good ... researchers report. They looked at data from more than ... who underwent treadmill tests between 1991 and 2009. Those ... chance of having high blood pressure at the start of ... with high levels of fitness. Of the more than ...
(Date:12/19/2014)... Dotinga HealthDay Reporter ... including ibuprofen, might slightly reduce your risk of developing ... of ibuprofen (Advil, Motrin) and naproxen (Aleve) appear to ... 15 percent, the researchers concluded after reviewing nine prior ... sun exposure. These painkillers "have potential ...
(Date:12/17/2014)... While countless companies tempt patients to buy hCG ... of their purchase. Not only is the sale of hCG ... patients who buy hCG online are typically receiving products that ... real hCG present. Illegal internet hCG is typically manufactured outside ... and may contain unknown fillers that can pose very serious ...
Breaking Medicine News(10 mins):Health News:New Superior Magnetic Necklace Relieves Migraine Headache 2Health News:Garth Brooks Tickets for Joe Louis Arena: Ticketability.com Becomes a Popular Destination for Discount Tickets for Garth Brooks’ Detroit Concerts Set for February 27-28 2Health News:Being Fit Keeps Blood Pressure in Check 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 3Health News:Diet Doc Reveals the Real Dangers for Those who Buy hCG Online 2Health News:Diet Doc Reveals the Real Dangers for Those who Buy hCG Online 3
... on the eve of its 35th Anniversary, Ronald McDonald House Charities (RMHC) ... that a little help goes a long way. The initiative, designed to ... three core programs: Ronald McDonald House, Ronald McDonald Family Room and the ... ...
... Healthcare, Inc. reminds,consumers to take full advantage of the ... expire by purchasing products to take,control of their personal ... nebulizers. , (Photo: ... (Photo: http://www.newscom.com/cgi-bin/prnh/20081204/AQTH541-b ) , ...
... available to couples , , THURSDAY, Dec. 4 (HealthDay News) ... have finished fertility treatments aren,t happy with the usual options ... eggs. , Most of 1,020 women surveyed said they were ... be thawed and thrown away, used by other women, given ...
... to Manage Stress and Promote Health during Holidays , ... As reports about the extent of the recession in the United ... Psychological Association (APA) finds that more than eight out of 10 ... impacting women and families most. , ...
... from 2000 to 2007, report shows , , THURSDAY, Dec. ... 74 percent between 2000 and 2007, according to a ... evidence that an international campaign to increase measles vaccination ... for Disease Control and Prevention report, the number of ...
... Stop and think for a moment. What do you remember ... will recall the smell of coffee brewing, while another will ... does the brain weave together these fragments, and how does ... by Prof. Itzhak Fried, a neurosurgeon at Tel Aviv University,s ...
Cached Medicine News:Health News: Ronald McDonald House Charities Brings People Together Like Never Before with First-Ever, Multi-Channel Social Networking Campaign : Charity Finds New Ways to Encourage Seasonal Giving in Tough Economic Times 2Health News: Ronald McDonald House Charities Brings People Together Like Never Before with First-Ever, Multi-Channel Social Networking Campaign : Charity Finds New Ways to Encourage Seasonal Giving in Tough Economic Times 3Health News:Maximize Flex Spending Account Funds Before They Expire 2Health News:Maximize Flex Spending Account Funds Before They Expire 3Health News:Women Unhappy With Disposal Options After Infertility Treatment 2Health News:Women Unhappy With Disposal Options After Infertility Treatment 3Health News:Financial Concerns Top List of Holiday Stressors for Women, Families with Children 2Health News:Financial Concerns Top List of Holiday Stressors for Women, Families with Children 3Health News:Financial Concerns Top List of Holiday Stressors for Women, Families with Children 4Health News:Worldwide Measles Deaths Drop Dramatically 2Health News:Worldwide Measles Deaths Drop Dramatically 3Health News:Unlocking the mysteries of memory 2
(Date:12/19/2014)... 18, 2014   Aratana Therapeutics, Inc . ... focused on the licensing, development and commercialization of ... results from its pivotal field study of AT-001 ... in dogs with osteoarthritis.  In the study, dogs ... that were statistically significant compared to placebo (p<0.05) ...
(Date:12/17/2014)... Revenue and earnings above the previous ... development In the past 2013/14 fiscal year (ended ... to EUR 4.287 billion (last year: EUR 4.190 billion) despite ... EUR 360 million. "Overall, 2013/14 was a successful fiscal year ... President and CEO of Carl Zeiss AG. "Thanks to our ...
(Date:12/17/2014)... , December 17, 2014 ... nothing less than a hub of information concerning the biopharmaceutical ... A further addition to the recently launched institutional ... and has now been enriched by a new chapter in ... A richly detailed and panoramic hub on the ...
Breaking Medicine Technology:Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5ZEISS Asserts its Position in Difficult Environment 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3
... 2011 Henry Schein, Inc. (NASDAQ: ... services to office-based practitioners, announced today that Ferdinand ... the CL King 9th Annual Best Ideas Conference 2011. The ... New York City. Henry Schein,s presentation is ...
... Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX ... for human disease, reported positive data from a recently ... dual inhibitor of the sodium glucose transporters 1 and ... effects on multiple parameters of glycemic control and cardiovascular ...
Cached Medicine Technology:Henry Schein to Present at the CL King 9th Annual Best Ideas Conference 2011 2LX4211 for Diabetes Shown to Reduce Fasting and Post-Prandial Blood Sugar in Healthy Subjects 2LX4211 for Diabetes Shown to Reduce Fasting and Post-Prandial Blood Sugar in Healthy Subjects 3LX4211 for Diabetes Shown to Reduce Fasting and Post-Prandial Blood Sugar in Healthy Subjects 4
... Trinity Biotech Uni-Gold™ Pf Malaria Test ... vitro, the presence of Plasmodium ... test is an antigen-capture assay detecting ... histidine- rich protein II (PfHRP- II), ...
High sensitive, specific one step immunochromatographic assay for human infectious disease...
Span Diagnostics Limited...
Malaria (P. fal.) Ag Rapid Test...
Medicine Products: