Navigation Links
RSNA: Atherosclerosis in Abdominal Aorta May Signal Future Heart Attack, Stroke

Oak Brook, IL (PRWEB) June 17, 2013

In a study of more than 2,000 adults, researchers found that two MRI measurements of the abdominal aorta — the amount of plaque in the vessel and the thickness of its wall — are associated with future cardiovascular events, such as a heart attack or stroke. Results of the study are published online in the journal Radiology.

“This is an important study, because it demonstrates that atherosclerosis in an artery outside the heart is an independent predictor of adverse cardiovascular events,” said the study’s lead author, Christopher D. Maroules, M.D., a radiology resident at the University of Texas Southwestern Medical Center in Dallas and lead author. “MRI is a promising tool for quantifying atherosclerosis through plaque and arterial wall thickness measurements.”

Atherosclerosis is a condition in which fat, cholesterol and other substances collect within the arteries, forming plaque. As plaque accumulates, the artery narrows, limiting blood flow. The condition can occur in any artery, including the cerebral (brain) and coronary (heart) arteries and the aorta, which carries oxygenated blood from the heart through the abdomen to the rest of body. The aorta is the largest artery body.

In the study, researchers analyzed abdominal MR images of 2,122 participants (mean age 44) in the Dallas Heart Study, a multiethnic population-based study of healthy adults from Dallas County, Texas. Two measurements were obtained from the MR images: mean abdominal aortic wall thickness, or the thickness of the vessel wall, and the amount of plaque buildup, referred to as the aortic plaque burden.

Following imaging, study participants were monitored for a period of 7.8 years. During that time, 143 participants experienced an adverse cardiovascular event in which arterial blood flow was obstructed, resulting in death or medical intervention. Researchers categorized the events as related to the heart (cardiac events) or to other arteries (called extra-cardiac vascular events) such as those in the brain or abdomen.

Of the 143 cardiovascular events, 34 were fatal. Seventy-three were non-fatal cardiac events, including heart attack or coronary revascularization, and 46 were non-fatal extra-cardiac vascular events, such as stroke or carotid revascularization.

Using the MRI measurements, the researchers found that increased abdominal aortic wall thickness correlated with a greater risk for all types of cardiovascular events. An increase in both wall thickness and aortic plaque burden was associated with an increased risk for non-fatal extra-cardiac vascular events.

“These MRI measurements may add additional prognostic value to traditional cardiac risk stratification models,” Dr. Maroules said.

MR imaging of the abdominal aorta is less technically challenging than other vascular imaging exams because of the large size of the vessel and its lack of proximity to a moving organ, such as the heart or the lungs. In addition, images of the abdominal aorta are often captured when patients undergo other exams, such as MRI of the spine or abdomen.

“The abdominal aorta is incidentally imaged on a regular basis,” Dr. Maroules said. “Radiologists can infer prognostic information from routine MRI exams that may benefit patients by identifying subclinical disease.”

According to Dr. Maroules, further MRI research will contribute to a better understanding of the progression of atherosclerosis, which scientists believe begins with a remodeling or thickening of the vessel wall prior to the buildup of plaque.

“Abdominal Aortic Atherosclerosis at MR Imaging Is Associated with Cardiovascular Events: The Dallas Heart Study.” Collaborating with Dr. Maroules were Eric Rosero, M.D., Colby Ayers, M.S., Ronald M. Peshock, M.D., and Amit Khera, M.D., M.Sc.

Radiology is edited by Herbert Y. Kressel, M.D., Harvard Medical School, Boston, Mass., and owned and published by the Radiological Society of North America, Inc. (

RSNA is an association of more than 51,000 radiologists, radiation oncologists, medical physicists and related scientists promoting excellence in patient care and health care delivery through education, research and technologic innovation. The Society is based in Oak Brook, Ill. (

For patient-friendly information on MRI, visit

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. RSNA: Concussion Patients Show Alzheimer’s-like Brain Abnormalities
2. RSNA: ‘Heading’ a Soccer Ball Could Lead to Brain Injury
3. RSNA: Digital Mammography Cancer Detection Rates May Vary Significantly
4. RSNA: Benefits of CT Outweigh Cancer Risks in Young Adults
5. RSNA: New Study Finds Brain Angioplasty and Stents Safe and Effective for Stroke Patients
6. Atherosclerosis in abdominal aorta may signal future heart attack, stroke
7. The search for an early biomarker to fight atherosclerosis
8. Atherosclerosis: Specific microRNAs promote inflammation
9. Islet transplant may slow progression of atherosclerosis
10. Autopsy-based study examines prevalence of atherosclerosis among US service members
11. Atherosclerosis found in HIV children
Post Your Comments:
(Date:11/26/2015)... Viejo, CA (PRWEB) , ... November 26, 2015 ... ... users a new set of retro-fused, self-animating trailer titles with ProTrailer: Vintage. This ... style options. These classically-influenced trailer titles work with any font, giving users limitless ...
(Date:11/26/2015)... ... November 26, 2015 , ... Indosoft Inc., developer and distributor ... application server to improve system efficiency and reliability. , The new Q-Suite 6 platform ... standards, the system avoids locking itself into a specific piece of software for many ...
(Date:11/25/2015)... ... 2015 , ... As part of a global movement to ... together who want to combine talents and resources to help create sustainable communities ... The non-profit launched its first major fundraiser on November 6, 2015 at Bent ...
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in the traditional and ... of traditional and far-infrared saunas. , For traditional saunas, Finnleo is offering ... Finnish sauna wood, and Finnleo uses only European Grade A Nordic White Spruce from ...
(Date:11/25/2015)... ... November 25, 2015 , ... TyloHelo Inc , ... accessories. , Sauna accessories help improve the bather experience in the sauna, and ... styles for the purist looking for simplicity in design to accessories that encourage ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... DUBLIN , November 26, 2015 /PRNewswire/ ... the addition of the "2016 Future ... Drugs of Abuse Testing Market: Supplier Shares, ... report to their offering. --> ... of the "2016 Future Horizons and ...
(Date:11/26/2015)... November 26, 2015 ... addition of the  "2016 Future Horizons ... Therapeutic Drug Monitoring (TDM) Market: Supplier ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
(Date:11/26/2015)... , Nov. 26, 2015 Research ... addition of the "2016 Future Horizons and ... (TDM) Market: Supplier Shares, Country Segment Forecasts, Competitive ... --> --> ... analysis of the Italian therapeutic drug monitoring market, ...
Breaking Medicine Technology: