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ROCKET AF trial suggests that digoxin increases risk of death in AF patients
Date:9/2/2014

creased risk of death due to a cardiovascular event.

Dr Patel said: "Our analysis represents an important observation with digoxin use in patients with atrial fibrillation. Digoxin could potentially be harmful and we need randomised trials to determine whether it can be used patients with atrial fibrillation. Our findings suggest that doctors should proceed with caution when using this drug for complex AF patients."

Dr Jeffrey Washam, a clinical pharmacist at the Duke Heart Center and first author of the abstract, said: "Despite being one of the oldest therapeutics in heart care, we still know very little regarding the risks and benefits of digoxin when used in patients with atrial fibrillation. In complex patients with atrial fibrillation, this analysis highlights the need for well-controlled studies to evaluate the efficacy and safety of digoxin."

Dr Patel concluded: "The results from this study should be confirmed in a prospective randomised trial."


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Contact: ESC Press Office
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European Society of Cardiology
Source:Eurekalert  

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ROCKET AF trial suggests that digoxin increases risk of death in AF patients
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