Navigation Links
REM sleep deprivation plays a role in chronic migraine
Date:6/22/2010

LOS ANGELES (June 23, 2010) Reporting at the American Headache Society's 52nd Annual Scientific Meeting in Los Angeles this week, new research shows that sleep deprivation leads to changes in the levels of key proteins that facilitate events involved in the underlying pathology of migraine.

Paul L. Dunham, Ph.D. and his team at Missouri State University's Center for Biomedical & Life Sciences sought to understand the mechanisms by which sleep disturbance increases the risk of migraine and may even trigger migraine.

"Previous clinical data support a relationship between sleep quality and migraine," said Dr. Durham, "so we used an established model of sleep deprivation to measure levels of proteins that lower the activation threshold of peripheral and central nerves involved in pain transmission during migraine. We found that REM sleep deprivation caused increased expression of the proteins p38, PKA, and P2X3, which are known to play an important role in initiating and sustaining chronic pain."

"So little is known about the biological mechanisms that underlie how certain factors trigger a migraine attack," said David Dodick, M.D., president of the AHS. "This is important work and this Missouri State team should be applauded for beginning to shed light on an area desperately in need of investigation."

The work was supported by Merck & Co.

More than 200 scientific papers and posters are being presented during the AHS meeting which is expected to draw some 500 migraine and headache health professionals including doctors, researchers, and specialists.


'/>"/>

Contact: Lauren Martiello
laurenm@mbooth.com
212-539-3291
American Headache Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Sleep Tips Web Site SleepBetter.org Expands The Bedtime Stories Project
2. Air Pollution Tied to Breathing Problems in Sleep
3. Possible link between sleep-disordered breathing and cardiovascular disease revealed
4. Purity Products Releases Ultimate Sleep Plus Melatonin
5. Sleep may help you become a Guitar Hero
6. Sleep colors your view of the world: Study suggests sleep may restore color perception
7. High-school seniors with excessive daytime sleepiness have an increased risk of depression
8. Sleep preference can predict performance of Major League Baseball pitchers
9. First-time parents daily sleep duration predicts their relationship satisfaction
10. CPAP therapy provides a memory boost for adults with sleep apnea
11. The best and worst work schedules: Shift start times can impact sleep and alertness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... ... April 28, 2016 , ... Sanford Health’s work ... A group of researchers and leaders from Sanford Health were selected to participate ... Its Cultural Impact ” and receive the 2016 Pontifical Key Innovation Award at ...
(Date:4/28/2016)... CA (PRWEB) , ... April 28, 2016 , ... La ... currently number one in Central America and is looking to grow their market share ... for such an exceptional brand as La Sirena Foods and indirectly with ...
(Date:4/28/2016)... ... 28, 2016 , ... Head Over Heels Athletic Arts’ gymnast, Brooklyn Varize, has ... be held at the University of Montana on April 28-May 1. Varize will compete ... , In order to qualify, Varize needed to place top seven all-around in her ...
(Date:4/28/2016)... ... April 28, 2016 , ... The ... a new CDISC standard, Clinical Trial Registry (CTR) XML. Clinical trial registries ... will make it possible to build applications that generate submissions for multiple, ...
(Date:4/28/2016)... ... 28, 2016 , ... Cosmetic Town, an online plastic surgery community, announces the ... was recently revamped and upgraded to allow even more interaction between doctors and patients ... , According to the senior editor of Cosmetic Town, “We are excited that our ...
Breaking Medicine News(10 mins):
(Date:4/26/2016)... , April 26, 2016 Hill-Rom Holdings, Inc. ... a management presentation at the Deutsche Bank 41 st ... 2:50 p.m. EDT. You are invited to listen ... http://ir.hill-rom.com/events.cfm or access it directly at http://edge.media-server.com/m/p/mr4uxgas . ... hour after conclusion of the live event and accessible at ...
(Date:4/26/2016)... DUBLIN , April 26, 2016 ... "Financial Assessment and Credit Risk Analysis of the Biological ... This comprehensive report analyzes the financial assessment ... China . The report provides readers ... key topics all market participants should be aware of. ...
(Date:4/26/2016)... April 26, 2016 ... 2016;9(1):16-20 DOI: http://doi.org/10.17925/USOR.2016.09.01.16 ... Published recently in US Ophthalmic Review, ... Davidson discusses how laser cataract surgery ... cataract surgery: the laser fragments the lens ...
Breaking Medicine Technology: