Navigation Links
REM sleep deprivation plays a role in chronic migraine
Date:6/22/2010

LOS ANGELES (June 23, 2010) Reporting at the American Headache Society's 52nd Annual Scientific Meeting in Los Angeles this week, new research shows that sleep deprivation leads to changes in the levels of key proteins that facilitate events involved in the underlying pathology of migraine.

Paul L. Dunham, Ph.D. and his team at Missouri State University's Center for Biomedical & Life Sciences sought to understand the mechanisms by which sleep disturbance increases the risk of migraine and may even trigger migraine.

"Previous clinical data support a relationship between sleep quality and migraine," said Dr. Durham, "so we used an established model of sleep deprivation to measure levels of proteins that lower the activation threshold of peripheral and central nerves involved in pain transmission during migraine. We found that REM sleep deprivation caused increased expression of the proteins p38, PKA, and P2X3, which are known to play an important role in initiating and sustaining chronic pain."

"So little is known about the biological mechanisms that underlie how certain factors trigger a migraine attack," said David Dodick, M.D., president of the AHS. "This is important work and this Missouri State team should be applauded for beginning to shed light on an area desperately in need of investigation."

The work was supported by Merck & Co.

More than 200 scientific papers and posters are being presented during the AHS meeting which is expected to draw some 500 migraine and headache health professionals including doctors, researchers, and specialists.


'/>"/>

Contact: Lauren Martiello
laurenm@mbooth.com
212-539-3291
American Headache Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Sleep Tips Web Site SleepBetter.org Expands The Bedtime Stories Project
2. Air Pollution Tied to Breathing Problems in Sleep
3. Possible link between sleep-disordered breathing and cardiovascular disease revealed
4. Purity Products Releases Ultimate Sleep Plus Melatonin
5. Sleep may help you become a Guitar Hero
6. Sleep colors your view of the world: Study suggests sleep may restore color perception
7. High-school seniors with excessive daytime sleepiness have an increased risk of depression
8. Sleep preference can predict performance of Major League Baseball pitchers
9. First-time parents daily sleep duration predicts their relationship satisfaction
10. CPAP therapy provides a memory boost for adults with sleep apnea
11. The best and worst work schedules: Shift start times can impact sleep and alertness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... ... December 05, 2016 , ... ... and relationship-marketing firm, announced today that nominations will be accepted from December ... (ISE®) Central Awards. , Awards include the Information Security Executive® of the ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... Meeting through tomorrow, December 6th, sparks a conversation about epilepsy, bearing down on ... in 26 people will be diagnosed with epilepsy within their lifetime. With such ...
(Date:12/5/2016)... , ... December 05, 2016 ... ... interoperability, today announced that the company will provide alerting technology to Central ... been recently awarded $1.7 million in federal funds as the sole sub-recipient ...
(Date:12/5/2016)... ... December 05, 2016 , ... Dr. Barry M. Weintraub, one ... Surgery, who recently participated in the 36th Annual Cutting Edge Aesthetic Symposium at the ... techniques for getting that perfect, yet natural-looking, nose. Dr. Weintraub, who is world-renowned for ...
(Date:12/5/2016)... , ... December 05, 2016 , ... ... Officer for the Florida Hospital West Florida Region. McGuinness brings experience in executive ... and engaging staff, physicians and leaders. , In her new role, that officially ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... , Dec. 5, 2016  BD (Becton, Dickinson ... global medical technology company, will demonstrate an enhanced technology ... management technologies, including the company,s leading Pyxis™ and Alaris™ ... Pharmacists (ASHP) 2016 Midyear Meeting being held in ... While national data show that approximately 68 ...
(Date:12/5/2016)... Research and Markets has announced the addition of the "Global ... and Demand Forecast to 2022" report to their offering. ... , , ... market is expected to grow at a CAGR of 4.5% during ... witnessing high growth, due to growing female geriatric population and increasing ...
(Date:12/5/2016)... England , December 5, 2016 ... Transitions to Deputy Chairman   ... on selectively targeting deubiquitylating enzymes (DUBs) to treat cancer, neurodegenerative ... has been appointed as non-executive Chairman, effective January 1 st ... of Mission Therapeutics as a non-executive Director in July 2015. ...
Breaking Medicine Technology: