Navigation Links
RELAX-AHF shows first positive findings in HFpEF patients
Date:5/26/2013

Lisbon, 26 May 2013: Serelaxin may be more effective for relieving dyspnea in heart failure with preserved ejection fraction (HFpEF) than reduced (HFrEF) during the first 24 hours, according to results from RELAX-AHF presented in today's late breaking trial session1 at the Heart Failure Congress 2013. Results were also presented from VIVIDD, the first trial of the anti-diabetes drug vildagliptin in patients with heart failure.

The Heart Failure Congress is the main annual meeting of the Heart Failure Association of the European Society of Cardiology and is being held 25-28 May in Lisbon, Portugal. Link to congress

Many patients with acute heart failure (AHF) have preserved ejection fraction but there is a lack of evidence based therapies for this population. In a sub-group analysis, investigators of the Relaxin in Acute Heart Failure (RELAX-AHF) trial addressed the question of whether serelaxin was equally effective in AHF patients with HFpEF and HFrEF.

RELAX-AHF was a double blinded, randomised, placebo controlled trial in which 1161 AHF patients from 96 sites were randomised to 48 hour infusion of serelaxin or placebo within 16 hours of presentation. The primary efficacy endpoint was the effect on dyspnea in the short term (6, 12 and 24 hours) and at 5 days. Secondary efficacy endpoints were cardiovascular death or rehospitalisation for heart or renal failure, and days alive and out of hospital through day 60. All-cause death and cardiovascular death through day 180 were also evaluated.

Serelaxin induced similar dyspnea relief in HFpEF and HFrEF patients at day 5 but was more effective in the HFpEF group in the first 24 hours. There were no differences between HFpEF and HFrEF patients in the effect of serelaxin on the secondary endpoints. Serelaxin had similar benefits on mortality in patients with HFpEF and HFrEF.

Presenter Professor Gerasimos Filippatos (Greece) said: "RELAX-AHF is the first trial to give positi
'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Voices Against Brain Cancer Comments on Study that Shows Cold Plasma’s Success Against Brain Cancer Cells
2. Second-generation TAVI device -- Lotus Valve -- shows good performance in REPRISE II
3. Study shows people can be trained to be more compassionate
4. Organic Cotton Sector Shows Signs of Stabilizing, Demonstrating Strength and Commitment of Producer Groups, According to 2011-12 Textile Exchange Farm & Fiber Report
5. Study shows that insomnia may cause dysfunction in emotional brain circuitry
6. Post-approval TAVI registry shows high rates of device success at 1 year
7. Poliovirus vaccine trial shows early promise for recurrent glioblastoma
8. Kaufman Shows People With Diabetes How to Use New Technology to Improve Their Lives
9. Peer-Reviewed Article Shows CLn® BodyWash an Effective Solution for Children with Eczema
10. DrugRisk Update Shows Increase in NuvaRing Blood Clot Lawsuits
11. Flax Seasoning Shows How Eating More Vegetables Will Improve Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2015)... London, UK (PRWEB) March 30, 2015 ... data and analytics professionals search for their next career ... over the next few years for those with skills ... site, at http://www.1potato.com , is a jobs aggregator, ... around the globe and indexing them individually to help ...
(Date:3/30/2015)... Salt Lake City, UT (PRWEB) March 30, 2015 ... for Americans to take stock of their eating habits and ... and long-term health in the future. According to a recent ... of daily calorie intake comes from snack food. Making healthy ... well-balanced diet, even for a busy society constantly on the ...
(Date:3/29/2015)... 2015 Elfster.com, the top-rated Secret Santa ... promotional plans to publicize its gift exchange generator technology ... Known as the leader in Secret Santa online gift ... adjacent markets can see the opportunities as well. , ... explained Peter Imburg, CEO of Elster.com. "With Christmas and ...
(Date:3/29/2015)... The culmination of one of the most exciting sporting ... Four invades Lucas Oil Stadium in Indianapolis IN. The ... excitement, buzzer-beaters, and of course, upsets. Throughout the dozens of ... and future professional products have been seen. In the end, ... that advanced through their regional bracket with the hopes of ...
(Date:3/29/2015)... Ore. (PRWEB) March 29, 2015 Youth ... Marion counties in Oregon to assess the feasibility of ... with emotional and behavioral problems and their families. , ... to select participants that will be provided technical assistance ... Oregon counties join six other national awardees chosen by ...
Breaking Medicine News(10 mins):Health News:New Global Job Site Launched for Big Data and Analytics Job Seekers 2Health News:Benefits of Healthy Snacking — HealthyYOU Vending Machines Offer 21 Healthy Snack Selections for People on the Go 2Health News:Benefits of Healthy Snacking — HealthyYOU Vending Machines Offer 21 Healthy Snack Selections for People on the Go 3Health News:Gift Exchange Generator Promotion Achieves Early Success, Announces Elfster 2Health News:Cheap 2015 Final Four Tickets: Ticket Down Slashes Kentucky Wildcats and Wisconsin Badgers Final Four Tickets at Lucas Oil Stadium and Issues Valuable Promo Code 2Health News:Youth Villages Partners with Two Oregon Counties to Advance Pay-for-Success Model to Help At-Risk Youth 2Health News:Youth Villages Partners with Two Oregon Counties to Advance Pay-for-Success Model to Help At-Risk Youth 3Health News:Youth Villages Partners with Two Oregon Counties to Advance Pay-for-Success Model to Help At-Risk Youth 4
... ... there are 6 key components of a successful strategic workforce planning process,” stated Jim ... components of strategic workforce planning and provides guidelines for implementing each of those 6 ... Waco, ...
... All Allied ... the health care industry. , ... (PRWEB) August 19, 2009 -- Today, All Allied Health Schools announced the launch of a new ... latest developments in the health care industry--and how these changes will affect health care careers ...
... Computed tomography (CT) scans are responsible for more than ... medical imaging exams. However, a newly adapted low-dose technique ... to reduce patient radiation resulting from CT up to ... September issue of the American Journal of Roentgenology ...
... led to fewer surgical deliveries, review shows , TUESDAY, ... increase the risk of Cesarean section delivery, according to ... Researchers reviewed available data on elective induction, in which ... it for medical reasons. Most of the studies included ...
... , , , ... Pharmaceutical Companies, Inc. (NYSE: PRX ) today announced ... final approval from the U.S. Food and Drug Administration for ... Clonidine TDS is a generic version of Boehringer Ingelheim,s ...
... , CHICAGO, Aug. 18 Synch-Solutions is ... on Inc. magazine,s 2009 list of the 5,000 fastest ... Synch-Solutions, reflecting the company,s strong and steady advancement - even in ... and technology solutions for organizations across multiple industry sectors. "As an ...
Cached Medicine News:Health News:Profiles International Releases New Study Identifying Key Factors for Strategic Workforce Planning 2Health News:All Allied Health Schools Launches "Health Care Community" 2Health News:All Allied Health Schools Launches "Health Care Community" 3Health News:Induced Labor May Prevent Need for Cesarean Section 2Health News:Par Pharmaceutical & Aveva Drug Delivery Systems Receive Final Approval to Market Generic Catapres TTS(R) 2Health News:Par Pharmaceutical & Aveva Drug Delivery Systems Receive Final Approval to Market Generic Catapres TTS(R) 3Health News:Synch-Solutions Named to Inc. Magazine's 2009 Ranking of the Fastest Growing Companies in the United States 2
(Date:3/27/2015)... 27, 2015 /CNW/ - Covalon Technologies Ltd. (the "Company" ... today announced the issuance of an aggregate of 30,000 ... and an aggregate of 120,500 stock options to employees ... vest over three years and will be exercisable for ... of $1.40 per stock option. About Covalon ...
(Date:3/27/2015)... , March 27, 2015 Object recognition technology ... visually impaired and elderly. The VelaSense ® ... to lead more independent, productive and fulfilling lives. VelaSense ... will allow users to identify objects from a one ... as create customized object databases for personal use. ...
(Date:3/27/2015)... LAKE CITY , March 27, 2015 Dynatronics ... J. Linder has been appointed to the Company,s Board ... created by the death in November 2014 of board member ... Rich Linder to our Board of Directors represents ... Cullimore, Jr. , chairman and president of Dynatronics.  "Rich is ...
Breaking Medicine Technology:Covalon Announces Issuance of Stock Options 2VelaSense Object Recognition Technology for the Blind was unveiled at Baruch College's CCVIP 8th Annual Conference 2Dynatronics Announces Appointment of Richard J. Linder to Board of Directors 2