Navigation Links
RA individuals from lower GDP countries keep working despite worse symptoms than richer countries
Date:6/12/2009

Copenhagen, Denmark, Friday 12 June 2009: Individuals diagnosed with rheumatoid arthritis (RA) in lower gross domestic product (GDP) countries (GDP below $11,000) are more likely to continue working despite higher disease activity and functional disability scores compared to their counterparts in higher GDP countries (GDP >$24,000) according to a new multinational study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.

Among 1,650 individuals from 30 countries whose symptoms had begun during the 2000's and who remained working after RA diagnosis, disability levels according to the Health Assessment Questionnaire (HAQ*) were 0.25 vs. 0.82 in men and 0.50 vs. 0.94 in women (p<0.001) in higher-GDP and lower-GDP countries, respectively, and the Disease Activity Scores (DAS28**) were 3.1 vs. 4.7 in men, and 3.5 vs. 4.8 in women (p<0.001). A Kaplan-Meier analysis (95% CI) showed that the probability of individuals continuing work for 2 years was 80% and the probability of continuing to work for 5 years was 68%.

Dr Tuulikki Sokka, Jyvskyl Central Hospital, Finland, who leads the project said: "Work disability is the most costly consequence of RA, and the rheumatology community would welcome better treatment strategies to effectively address this. However, real-life data from 30 countries indicate that work disability is still a major issue in early RA during this decade, and especially in low-GDP countries where people continue to work with considerable disease activity and functional limitations."

The results of the study showed that, at the time of symptom onset, 68% (<65 years) of subjects were working, but 35% of these reported that they subsequently became 'work disabled' due to RA. Notably, this proportion of people with RA was similar in both lower and higher GDP countries at 5 years.

Subjects for the study were derived from The Quantitative Standard Monitoring of Patients with RA (QUEST-RA) database of 7,568 patients (80% females, mean age 56 years, mean disease duration 11 years) who receive standard care from rheumatologists. Patients from 83 sites in the following 30 countries were studied: Argentina, Brazil, Canada, Denmark, Egypt, Estonia, Finland, France, Germany, Greece, Hungary, India, Ireland, Italy, Japan, Kosovo, Latvia, Lithuania, Morocco, the Netherlands, Norway, Poland, Russia, Serbia, Spain, Sweden, Turkey, United Arab Emirates, United Kingdom, and the United States.

In the study, HAQ (0-3) was used to measure everyday disability and the DAS28 (0-10) to measure disease activity. Data concerning work status/disability were based entirely on results of a patient self-reporting questionnaire which included multiple choice questions about work status at the time of the first symptoms of RA compared to current work status. Patient self-perceived work disability was queried with questions such as: 'Are you work disabled because of RA?' 'If so, since when?' Kaplan-Meier statistics were applied to measure the survival function of the data over time.

* HAQ (Health Assessment Questionnaire) is a patient self-report questionnaire to measure an individual's physical functioning. It assesses ability to undertake everyday activities such as dressing, eating and walking, and whether assistance from another person or disability aids is required. A higher score indicates greater disability.

** DAS28 (Disease Activity Score) is an index used by physicians to measure how active an individual's RA is. It assesses number of tender and swollen joints (out of a total of 28), the erythrocyte sedimentation rate (ESR, a blood marker of inflammation), and the patient's 'global assessment of global health'. A higher score indicates more active disease.


'/>"/>

Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-789-438-6425
European League Against Rheumatism
Source:Eurekalert

Related medicine news :

1. Companion Global Healthcare Inc. Offers Additional Hospital Choices to Employers, Individuals Looking to Save on Fully Credentialed Health Care
2. Ironman Competitor with Diabetes Inspires Individuals with Diabetes to Live Without Limits
3. Explorers Bounty Coffees and Chocolates Helping Individuals Reverse the Aging Process
4. QualityMetric Offers Way to Measure the Impact of Sleep Problems on Individuals and Groups
5. Eleventh Annual Welcome Back Awards Program Honors Individuals who Positively Impact the Depression Community
6. arc Thrift Stores to Honor Individuals and Businesses Who Support People With Developmental Disabilities
7. NSVRC Honors 12 Individuals With Award for Sexual Assault Awareness Month
8. Omega-3s May Benefit Newborns, Menopausal Women and Obese Individuals
9. HealthForumOnline Offers New Online CE Course on Working with Transgender Individuals
10. Proposed Settlement Will Make Up to $28 Million Available to Individuals Who Purchased and Companies That Reimbursed for Paxil CR(R)
11. Improved Genetic Test Product Empowers Individuals to Better Understand Their Unique Nutritional Needs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... ... 24, 2017 , ... The results from the American Cancer Society’s ... for prostate cancer patients: incidents of cancer is down as is the likelihood of ... death rate has dropped from its peak of 215.1 in 1991 to 161.2 in ...
(Date:1/24/2017)... ... ... American Family Care (AFC) has opened a new 4,000+ square foot state-of-the-art urgent ... area. The Bedford clinic will be the nineteenth location opened by AFC in Massachusetts ... Dr. Kristina Orio. Adams and Orio also independently own and operate AFC clinics in ...
(Date:1/24/2017)... ... January 24, 2017 , ... ... natural supplement for relieving premenstrual syndrome, or PMS . , Most women ... These symptoms can include cramps, constipation, irritability, headaches, fatigue, and other discomfort. ...
(Date:1/24/2017)... ... ... Would Have Dreamed: A Novel of Miracles”: a beautiful and poignant glimpse into the ... in her life. “Who Would Have Dreamed: A Novel of Miracles” is the creation of ... , Sharon shares that she started her spiritual journey later in life, but ...
(Date:1/24/2017)... ... January 24, 2017 , ... “The Octagon of Spiritual Balances”: a ... Balances” is the creation of published author, Pastor Bernard J. Weathers, pastor of Word ... bachelor degree in religious education and a master degree in theology. , ““The Octagon ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... , Jan. 23, 2017 Research and Markets ... - Forecast to 2021" report to their offering. ... The interventional radiology products ... USD 6.35 Billion in 2016, at a CAGR of 4.8%. This ... The major factors driving the growth of this market are ...
(Date:1/23/2017)... , Jan. 23, 2017 7D ... 510(k) clearance from the U.S. Food and Drug ... Health Canada enabling the North American commercial launch ... system for spine surgery, the 7D Surgical System.  ... cutting-edge 3D optical technologies and machine vision algorithms ...
(Date:1/23/2017)... -- The American Pharmacists Association (APhA) is excited about ... Underserved Areas Enhancement Act (H.R. 592) in ... previously introduced in the 114 th session of ... pharmacists and their patient care services. Sponsors ... (R-KY), G.K. Butterfield (D-NC), Tom Reed ...
Breaking Medicine Technology: