Navigation Links
Queen's scientists develop 'magic bullet' nanomedicine for Acute Lung Injury
Date:5/14/2013

Researchers at Queen's University Belfast have devised a 'magic bullet' nanomedicine which could become the first effective treatment for Acute Lung Injury or ALI, a condition affecting 20 per cent of all patients in intensive care.

There are 15,000 cases of ALI every year in the UK. The main causes are road traffic accidents and infections, and many with the condition die as a result of lung failure.

ALI patients can become critically ill and develop problems with breathing when their lungs become inflamed and fill with fluid. These patients frequently require ventilators to aid breathing within an ICU hospital unit. An ICU bed costs the NHS in excess of 1800 per day.

There are currently no effective treatments for this serious condition, but in a joint collaboration between the School of Pharmacy and Centre for Infection and Immunity at Queen's, a team of scientists and clinicians have developed a new drug that could revolutionise clinical management of patients in intensive care units.

Their new drug is a nanoparticle, measuring around one billionth of a metre. The patient can inhale it, taking the drug directly into the lungs and to the point of inflammation. Current treatments are unable to target directly the inflammation and can result in unpleasant side effects.

Speaking about the development, Professor Chris Scott from the School of Pharmacy, who is leading the research, said: "Nanoparticles are perhaps one of the most exciting new approaches to drug development. Most research in the area focuses on how the delivery of drugs to the disease site can be improved in these minute carriers. Our own research in this area focuses on how nanoparticles interact with cells and how this can be exploited to produce therapeutic effects both in respiratory disease and cancer."

The new nanoparticle from Queen's has a surface which allows it to recognize and bind to immune cells called macrophages in the lungs - key to the uncontrolled infl
'/>"/>

Contact: Claire O'Callaghan
c.ocallaghan@qub.ac.uk
Queen's University Belfast
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Block O'Toole & Murphy, LLP Recovers $4,650,000 For Construction Laborer Who Fell In Queens Warehouse
2. Queens University of Charlotte Introduces Online Master of Science in Nursing
3. Independence Residences Inc. Announces Affiliation with Queens Parent Resource Center (QPRC)
4. Scientists Discover More Genetic Clues to Testicular Cancer
5. Advocacy Group Awards $300,000 to Young Scientists in Search of a Cure for Bladder Cancer
6. Scientists define a new mechanism leading to tumor hypoxia
7. Scientists Explore Secrets of the Well-Hit Fastball
8. Monell scientists identify critical link in mammalian odor detection
9. Duke scientists build a living patch for damaged hearts
10. Scientists revolutionize the creation of genetically altered mice to model human disease
11. Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... date, more than 1,500 investor-families have received permanent green cards (I-829 petition approval) ... , The I-829 petition is the final step of the EB-5 visa process ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... borders seldom arise at the most convenient time for everyone involved. These occasions ... help. , Universal Translation Services has real people available to handle ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... MAP Recovery Network, the Premier Outcomes-Driven Provider Network. It is the first-ever, ... dedicated to the provision of quality addiction treatment and the utilization of ...
(Date:9/1/2015)... Sarasota, Fla. (PRWEB) , ... September 01, 2015 , ... ... to be one of the first in the area to offer RADIESSE® filler treatment ... help to reduce the prominence of tendons and veins in the hands, delivering smooth, ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... recently sponsored an educational workshop for physician assistants (PAs) practicing in orthopedics. The ... and Zeel™” was held by Dr. Erick Salado, an orthopedic surgeon at South ...
Breaking Medicine News(10 mins):Health News:CanAm Enterprises Reaches Another Milestone with More Than 1,500 I-829 Petition Approvals 2Health News:Universal Translation Services Provides Quality Translations 24 Hours a Day Including Weekends 2Health News:Universal Translation Services Provides Quality Translations 24 Hours a Day Including Weekends 3Health News:MAP Health Management Launches the MAP Recovery Network 2Health News:SkinSmart Dermatology in Sarasota is Now Offering RADIESSE to Rejuvenate Hands 2Health News:SkinSmart Dermatology in Sarasota is Now Offering RADIESSE to Rejuvenate Hands 3Health News:New Hope for Patients Seeking Treatment of Osteoarthritis Knee Pain 2Health News:New Hope for Patients Seeking Treatment of Osteoarthritis Knee Pain 3
... cardiologists have searched for ways to see dangerous blood ... at Washington University School of Medicine in St. Louis ... and make them visible to a new kind of ... a Washington University cardiologist at Barnes-Jewish Hospital, these nanoparticles ...
... unexpected benefit of osteoporosis treatment that people taking ... without osteoporosis, they appear to be gaining an extra ... the Journal of Clinical Endocrinology and Metabolism , ... John Eisman, from Sydney,s Garvan Institute of Medical Research, ...
... German . Lung tumors are the number one ... is lung cancer. Each year, there are 50,000 new cases of ... detected, the greater the chance of healing the patient. But early ... chronic inflammatory reactions. To get a more complete diagnosis, the patient ...
... delivered intranasally, vaccine was found to be more effective, Funding ... PROVIDENCE, R.I. A new study led ... University of Rhode Island (URI) and EpiVax. Inc, a privately ... potential vaccine capable of reducing colonization of Helicobacter pylori ...
... ( www.elsevier.com ), the leading global publisher of ... announced today that it acquired the oncology portfolio ... LP., (operated as Cancer Information Group). The journals ... articles that disseminate cutting-edge data to physicians, medical ...
... HealthDay Reporter , TUESDAY, Feb. 1 (HealthDay News) -- ... blood pressure and cholesterol levels -- both primary risk ... According to the latest report from the U.S. Centers ... have hypertension (high blood pressure), about the same proportion ...
Cached Medicine News:Health News:New nanoparticles make blood clots visible 2Health News:New nanoparticles make blood clots visible 3Health News:An extra 5 years of life an unexpected benefit of osteoporosis treatment 2Health News:Early detection of lung cancer 2Health News:New study identifies potential vaccine to prevent gastritis, ulcer disease, gastric cancer 2Health News:Half of Adults Have Hypertension or High Cholesterol: CDC 2Health News:Half of Adults Have Hypertension or High Cholesterol: CDC 3
(Date:8/31/2015)... 31, 2015 Thousands of people will peacefully ... the opioid addiction epidemic at dozens of rallies across ... 2008, the United States has ... prescription opioids and heroin, yet the President has never ... worded letter to President Obama , rally organizers ...
(Date:8/31/2015)... ALBANY, New York , August 31, 2015 ... Research report states that the global cardiovascular monitoring ... in 2012 and is predicted to reach a ... at a CAGR of 9.7% between 2013 and ... Monitoring and Diagnostic Devices Market (ECG, Holter Monitors, ...
(Date:8/31/2015)... Pa. , Aug. 31, 2015  The departments ... an event today at Gaudenzia Concept 90 to raise ... drug overdose crisis in Pennsylvania ... treatment and focus on recovery through the Building ... many Pennsylvanians are dying every day to a disease ...
Breaking Medicine Technology:Obama Administration's Neglect of Opioid Crisis Prompts Rallies in Many States 2Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 2Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 3Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 4Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 5Pennsylvania Departments of Drug & Alcohol Programs and Health Kick-off Second Annual Building Bridges to Recovery Initiative 2
... MOUNTAIN VIEW, Calif., Aug. 12 As more and more ... spinal surgery techniques, the negatives of the spinal fusion market ... five years, the industry expects to see a steady inflow ... in the market. (Logo:   http://www.medicaldevices.frost.com ), ...
... Nev., Aug. 13 PDL BioPharma, Inc. (PDL) (Nasdaq: ... and the PDL BioPharma logo are considered trademarks of ... This press release contains forward-looking statements. Each ... results may differ materially from those, express or implied, ...
Cached Medicine Technology:Frost & Sullivan: Innovative Products and Technologies Strengthen U.S. Spinal Surgery Market 2PDL BioPharma Receives Letter from Genentech Relating to European Patents 2
... Mammography has been FDA approved, and represents ... It is the first and only mammography ... - the highest available. SenoScan's larger field ... breast support is more comfortable and helps ...
... P3000 heralds a new concept in pupillometry, designed ... optical system developed for the P2000. We ... which we have paid particular attention to the ... new system is extremely flexible, allowing you to ...
... most useful features is the PupilFit software ... analysis of the pupil images, producing accurate, ... The fitted circle is shown as a ... that the measurement ismeaningful, and not just ...
... urine analyzer that ensures accurate results, test ... by reducing "hands on" operator time. And ... ideal fit for work areas large or ... is designed for continuous sample processing of ...
Medicine Products: