Navigation Links
Queen's scientists develop 'magic bullet' nanomedicine for Acute Lung Injury
Date:5/14/2013

Researchers at Queen's University Belfast have devised a 'magic bullet' nanomedicine which could become the first effective treatment for Acute Lung Injury or ALI, a condition affecting 20 per cent of all patients in intensive care.

There are 15,000 cases of ALI every year in the UK. The main causes are road traffic accidents and infections, and many with the condition die as a result of lung failure.

ALI patients can become critically ill and develop problems with breathing when their lungs become inflamed and fill with fluid. These patients frequently require ventilators to aid breathing within an ICU hospital unit. An ICU bed costs the NHS in excess of 1800 per day.

There are currently no effective treatments for this serious condition, but in a joint collaboration between the School of Pharmacy and Centre for Infection and Immunity at Queen's, a team of scientists and clinicians have developed a new drug that could revolutionise clinical management of patients in intensive care units.

Their new drug is a nanoparticle, measuring around one billionth of a metre. The patient can inhale it, taking the drug directly into the lungs and to the point of inflammation. Current treatments are unable to target directly the inflammation and can result in unpleasant side effects.

Speaking about the development, Professor Chris Scott from the School of Pharmacy, who is leading the research, said: "Nanoparticles are perhaps one of the most exciting new approaches to drug development. Most research in the area focuses on how the delivery of drugs to the disease site can be improved in these minute carriers. Our own research in this area focuses on how nanoparticles interact with cells and how this can be exploited to produce therapeutic effects both in respiratory disease and cancer."

The new nanoparticle from Queen's has a surface which allows it to recognize and bind to immune cells called macrophages in the lungs - key to the uncontrolled infl
'/>"/>

Contact: Claire O'Callaghan
c.ocallaghan@qub.ac.uk
Queen's University Belfast
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Block O'Toole & Murphy, LLP Recovers $4,650,000 For Construction Laborer Who Fell In Queens Warehouse
2. Queens University of Charlotte Introduces Online Master of Science in Nursing
3. Independence Residences Inc. Announces Affiliation with Queens Parent Resource Center (QPRC)
4. Scientists Discover More Genetic Clues to Testicular Cancer
5. Advocacy Group Awards $300,000 to Young Scientists in Search of a Cure for Bladder Cancer
6. Scientists define a new mechanism leading to tumor hypoxia
7. Scientists Explore Secrets of the Well-Hit Fastball
8. Monell scientists identify critical link in mammalian odor detection
9. Duke scientists build a living patch for damaged hearts
10. Scientists revolutionize the creation of genetically altered mice to model human disease
11. Scientists Pinpoint Most Major Genes Behind Deadly Blood Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... In today’s world, a good night’s sleep has become ... apnea (a medical problem where the airway collapses during sleep ... the rest they need to face their daily challenges. ... million people in the United States alone have sleep apnea. ... of those treated, many cannot tolerate their prescribed medical device ...
(Date:8/30/2014)... (PRWEB) August 30, 2014 "My niece ... knowing that, at any moment, her fever might get ... to keep me well aware of how she was ... the TEMP ALARM to continuously monitor a child's temperature. ... a fever. This ensures that prompt medical care can ...
(Date:8/30/2014)... 30 August 2014: Transvenous lead extraction (TLE) is clinically ... data from the European Lead Extraction ConTRolled (ELECTRa) registry ... 2014 by Dr Maria Grazia Bongiorni, chair of the ... of cardiac implantable electronic devices (CIED) implant procedures has ... number of complications has increased and leads are often ...
(Date:8/30/2014)... The new review published by Daily Gossip ... Karen Brimeyer, who wanted to make her guide accessible to ... is now easy to find in the form of an ... the author of the new method shares all her tips ... writes in its review that the leaky gut syndrome can ...
(Date:8/30/2014)... Jake W., 18, is completing his high ... Back2Basics Outdoor Adventures transition program known as Beyond the ... I can actually start on a real career path,” said ... done.” , He has six months of sobriety under his ... choose to continue on to the Beyond the Basics transition ...
Breaking Medicine News(10 mins):Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Transvenous lead extraction clinically successful in 98 percent of cases 2Health News:Transvenous lead extraction clinically successful in 98 percent of cases 3Health News:Leaky Gut Cure Review Reveals Unique Method to Stop Chronic Symptoms 2
... In a unique research effort, kin cancer researchers from all ... umbrella to help the world understand what exactly their risk ... the international Genomel consortium based in Leeds, England has been ... will lead the teams from around the world. All these ...
... Institute of Neurological Disease have found that the protein ... //that acts by inactivating the conversion of glucose into ... released from apoE. ,The apoE protein is ... not providing the glucose present in the brain to ...
... population runs a risk that is four times higher ... to the Australian Institute of Health and Welfare (AIHW).// ... attack. Between 2001 and 2003, almost 21,000 people aged ... diabetes. ,During the period under review ...
... religion plays in a patient's life positively affect physician bedside ... and no, for male medicos.// ,According to a ... Medical Journal, patients want their physicians to be aware of ... issues with them, especially if they are preparing for death. ...
... from an acute shortage of nurses, with some schools having ... across the country in schools on a fulltime basis.// This ... federal guidelines call for a nurse for every 750 students. ... when compared to other parts of the country. Because of ...
... his new book 'The Failure of Democratic Nation Building: Ideology ... that Democracy should not or cannot be forcibly thrusted on ... an intrinsic need for hierarchical and authoritarian social and political ... hand requires unique conditions before it is accepted by the ...
Cached Medicine News:Health News:Religious sensitivity of medicos gender-dependent 2Health News:School Children Put To Risk Due To Shortage Of Nurses 2
(Date:8/29/2014)... MARLBOROUGH, Mass. , Aug. 29, 2014 /PRNewswire/ ... ) prospective, multinational study on stent removability and ... strictures has been published in the August issue ... The multinational study 1 is being conducted ... removal of fully covered self-expanding metal stents (FCSEMS) ...
(Date:8/29/2014)... 29, 2014 Thoratec Corporation (NASDAQ: ... support therapies to save, support and restore failing hearts, ... Morgan Stanley Global Healthcare Conference on Wednesday, September 10. ... Chief Executive Officer, will provide an update on the ... a.m., Pacific Daylight Time).   A webcast ...
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Global Peptide Cancer Therapeutics Market & Pipeline Insight ... The conventional methods developed to prevent and eradicate the ... treatment. These methods are confined to low specificity, safety ... researchers to look for a better solution. It has ...
Breaking Medicine Technology:Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2
... Mass.--(BUSINESS WIRE)--Jun 5, 2007 - Elixir,Pharmaceuticals, Inc., ... as a potential method for regulating,metabolism, decreasing ... were presented in poster sessions during ENDO ... held in Toronto,Canada. Elixir is focused on ...
... Multinational Phase III Study Provides Further Evidence ... in the Treatment,of Rheumatoid Arthritis, BASEL, Switzerland, ... the second multinational phase III Actemra,(tocilizumab) study, ... a greater proportion of patients treated with ...
Cached Medicine Technology:Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 2Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 3Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 4New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 2New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 3New Data Confirms Significant Improvement of Disease Signs and,Symptoms in Patients with Rheumatoid Arthritis 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: