Navigation Links
Queen's researchers pioneer needle-free test for premature babies
Date:4/13/2011

Scientists at Queen's University Belfast have pioneered a new needle-free test to take the sting out of medicine testing in premature babies. The research will not only lead to greater accuracy in prescribing, but will also significantly reduce the trauma of such tests for newborn infants and their families.

In the first published research project worldwide on this new approach to testing medicines in children, the findings were announced in leading US medical journal Pediatrics.

The study, which involves the use of blood spots obtained from a simple heel-prick, took place in the Belfast Hospital for Sick Children and the School of Pharmacy at Queen's.

The research was carried out by a team from the University's School of Pharmacy in partnership with the Regional Neonatal Unit in the Royal Maternity Hospital. It was funded by the Health and Social Care Research and Development Office (HSC R&D) and Action Medical Research.

Principal Investigator, Queen's Professor of Pharmacy Practice James McElnay said: "This type of testing will obviously reduce the discomfort of medicine testing in these vulnerable patients. What is even more important, however, is that it will ensure maximum accuracy in calculating the most appropriate dose of a medicine for a sick child.

"Some 80 per cent of infants in intensive care in hospitals receive medicines which have not been appropriately tested or licensed for use in such young patients, and the dosage is usually calculated based on licensed doses for adults or older children. Sizable blood samples are then required to measure the concentrations of the drug in the infant's bloodstream.

"Our work opens up opportunities for using the same approach to study other medicines which are used in this manner in children, and we are currently studying a number of these."

The Queen's study involved the antibiotic metronidazole. The research team used single drops of blood collected on blotting paper from premature infants who were receiving the medicine as part of their routine care. The 'spots' were dried, analysed in the University's School of Pharmacy, and the results used to develop dosage guidance for doctors.


'/>"/>

Contact: Anne Langford
a.langford@qub.ac.uk
028-909-75310
Queen's University Belfast
Source:Eurekalert

Related medicine news :

1. New York Personal Injury Lawyers Concerned About Toyota Accident in Queens
2. ENT and Allergy Associates Welcomes Tamekia L. Wakefield, MD, Further Reinforcing its Pediatric Sinus Expertise and Capabilities in Queens
3. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
4. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
5. Researchers discover new way to kill pediatric brain tumors
6. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
7. Researchers create drug to keep tumor growth switched off
8. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
9. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
10. Clemson researchers develop hands-free texting application
11. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... (PRWEB) , ... January 19, 2017 , ... ... owned insurance agency which serves Lawrenceville, New Jersey and the surrounding area, ... , Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease or ...
(Date:1/19/2017)... , ... January 19, 2017 , ... ... the 2017 Spring Create Real Impact contest from Impact Teen Drivers and California ... http://www.createrealimpact.com . , Educational grants totaling $15,000 will be awarded for ...
(Date:1/19/2017)... ... January 19, 2017 , ... Bill Howe Plumbing, Heating & Air ... Heart Association; “Howe” Healthy is Your Heart Drawing Contest The drawing contest ... year, Bill Howe Plumbing, Heating & Air receives over 600 entries. The culmination of ...
(Date:1/19/2017)... ... January 19, 2017 , ... Sales Focus Inc. (SFI), a Maryland-based sales ... market. , Over the past 20 years SFI has been recognized as the world’s ... six new clients into the US market. The new clients include: Panacea Pro, ...
(Date:1/19/2017)... Atlanta, Georgia (PRWEB) , ... January 19, 2017 ... ... Reconstructive Surgeons hosts the Atlanta Breast Surgery Symposium, a conference where hundreds of ... latest advancements in breast surgery. Covering topics from cosmetic breast augmentation ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... , Jan. 19, 2017 Conference Call and Webcast to ... ) today announced it will release results for the fourth quarter ... ... host a conference call at 4:30 PM ET on Wednesday, February ... full year 2016 financial results and other corporate activities. To participate ...
(Date:1/19/2017)...  Stealth BioTherapeutics Inc. ( Stealth ), a clinical-stage ... announced new additions to its senior leadership team: ... and Daniel Geffken as interim Chief Financial ... , Pharm.D. has been promoted to Chief Clinical Development ... Doug and Daniel to our management team, as both ...
(Date:1/19/2017)... 19, 2017  Abaxis, Inc. (NasdaqGS: ABAX ... instruments and consumables for the medical and veterinary markets ... financial results for the third quarter fiscal year 2017, ... 4:15 p.m. ET on Thursday, January 26, 2017.  The ... fiscal year 2017 after the market closes on Thursday, ...
Breaking Medicine Technology: