Navigation Links
Queen's researchers pioneer needle-free test for premature babies
Date:4/13/2011

Scientists at Queen's University Belfast have pioneered a new needle-free test to take the sting out of medicine testing in premature babies. The research will not only lead to greater accuracy in prescribing, but will also significantly reduce the trauma of such tests for newborn infants and their families.

In the first published research project worldwide on this new approach to testing medicines in children, the findings were announced in leading US medical journal Pediatrics.

The study, which involves the use of blood spots obtained from a simple heel-prick, took place in the Belfast Hospital for Sick Children and the School of Pharmacy at Queen's.

The research was carried out by a team from the University's School of Pharmacy in partnership with the Regional Neonatal Unit in the Royal Maternity Hospital. It was funded by the Health and Social Care Research and Development Office (HSC R&D) and Action Medical Research.

Principal Investigator, Queen's Professor of Pharmacy Practice James McElnay said: "This type of testing will obviously reduce the discomfort of medicine testing in these vulnerable patients. What is even more important, however, is that it will ensure maximum accuracy in calculating the most appropriate dose of a medicine for a sick child.

"Some 80 per cent of infants in intensive care in hospitals receive medicines which have not been appropriately tested or licensed for use in such young patients, and the dosage is usually calculated based on licensed doses for adults or older children. Sizable blood samples are then required to measure the concentrations of the drug in the infant's bloodstream.

"Our work opens up opportunities for using the same approach to study other medicines which are used in this manner in children, and we are currently studying a number of these."

The Queen's study involved the antibiotic metronidazole. The research team used single drops of blood collected on blotting paper from premature infants who were receiving the medicine as part of their routine care. The 'spots' were dried, analysed in the University's School of Pharmacy, and the results used to develop dosage guidance for doctors.


'/>"/>

Contact: Anne Langford
a.langford@qub.ac.uk
028-909-75310
Queen's University Belfast
Source:Eurekalert

Related medicine news :

1. New York Personal Injury Lawyers Concerned About Toyota Accident in Queens
2. ENT and Allergy Associates Welcomes Tamekia L. Wakefield, MD, Further Reinforcing its Pediatric Sinus Expertise and Capabilities in Queens
3. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
4. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
5. Researchers discover new way to kill pediatric brain tumors
6. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
7. Researchers create drug to keep tumor growth switched off
8. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
9. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
10. Clemson researchers develop hands-free texting application
11. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... ... ... Shah MD, MBA has joined the Retina Group of New York (RGONY) specializing ... M. Maisel, MD and has been providing tertiary medical and surgical retinal care on Long ... expectations amongst her peers. Growing up in a family of doctors, Dr. Shah emulated ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... ensure moisture measurements are consistently correct. However, regular performance testing is often ... TOLEDO offers a solution: SmartCal™ . This innovative test substance offers ...
(Date:12/5/2016)... ... December 05, 2016 , ... A newly ... significantly improves the reproducibility and accuracy of placing precordial electrodes with little cognitive ... Over the last 60 years, studies have shown that single electrode misplacement is ...
(Date:12/4/2016)... ... December 03, 2016 , ... "Perfect Harmony ... more tools allowing FCPX editors to create professional looking video in a matter ... Perfect Harmony contains a beautifully designed 3D environment for placing in personal media. ...
(Date:12/4/2016)... ... December 03, 2016 , ... ... Company in the Dallas area” Tuesday evening at the 26th Annual SMU Cox ... by SMU's Cox School’s Caruth Institute for Entrepreneurship. Dallas 100™, co-founded by the ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Ill. , Dec. 5, 2016 For ... score on the 2017 Human Rights Campaign Foundation,s ... The CEI is a national benchmarking tool used to ... bisexual, and transgender (LGBT) employee equality. For ... Survey to help companies gauge their equality efforts, culture ...
(Date:12/5/2016)... 2016 Research and Markets has announced the addition ... to 2021" report to their offering. ... , , The global spinal ... 2021, at a CAGR of 5.3% from 2016 to 2021. Factors such ... cases, increasing government spending on healthcare, and rising income levels are propelling ...
(Date:12/5/2016)... , December 5, 2016 PharmaBoardroom today releases ... . ... This report offers companies, investors, policymakers, and stakeholders crucial insight ... of Europe , home to some of the world,s ... pharmaceutical companies in Novartis and Roche, and with a number one ranking ...
Breaking Medicine Technology: