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Queen's research gives fresh hope to couples with 'unexplained infertility'
Date:11/14/2012

tment and increase their chances of having a baby."

The study also has a second major finding. It is the first study to show that the chances of having a baby after IVF is closely related to the amount of DNA damage a man has in each of his sperm. A little damage is normal (under 15 per cent per sperm), as is seen in the sperm of fertile men. But if the damage reaches clinically important levels (high sperm DNA damage more than 25 per cent per sperm) it will reduce the couples' chances of a family, even with some forms of fertility treatment. These findings are the latest in a series of studies performed by the internationally recognised male fertility research team based at Queen's Centre for Public Health involving over 500 couples.

The research was carried out using a unique test for male fertility called the SpermComet. Professor Lewis said: "We at Queen's have developed the SpermComet, which is a unique test for male infertility that measures damaged DNA in individual sperm providing all couples with specific information about the causes and extent of their infertility. This test can predict the success of infertility treatments and fast-track couples to the treatment most likely to succeed, leading to reduced waiting times and improved chances of success.

"With one million couples worldwide requiring fertility treatment, these new research findings will give many fresh hope of having a family." Professor Lewis, in partnership with Queen's venture spinout arm, QUBIS, has now set up a company called Lewis Fertility Testing Ltd which is already marketing the test. For more information visit www.lewisfertilitytesting.com


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Contact: Claire O'Callaghan
c.ocallaghan@qub.ac.uk
Queen's University Belfast
Source:Eurekalert

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