Navigation Links
Queen's University study aims at early diagnosis for ADHD and Parkinson's disease
Date:7/13/2009

Eye movement tests developed by Queen's University researchers to aid in understanding childhood brain development and healthy aging may also help in the diagnosis of Attention Deficit Hyperactivity Disorder and detecting the early onset of Parkinson's disease. The project has received close to $1 million in recent funding from the Canadian Institutes of Health Research (CIHR).

"An important aspect of what makes us human is the ability to control our behaviour," says Physiology professor Douglas Munoz, who leads the study. "Our project investigates how the brain provides this control by observing eye movements. Our experiments have been designed to combine high speed eye movement recording with modern brain imaging techniques to identify brain regions that control our behaviour."

To test this, the team designed a simple yet ingenious experiment. Participants from a wide range of age groups were placed in a magnetic resonance imaging unit that measured their brain activity. While in the unit, they were shown a series of lights and asked to move their eyes toward or away from the lights. The speed and accuracy of their eye movements were recorded and correlated to the activity being documented in specific areas of their brains.

The study showed that at early ages, children scored low. Although they understood the task, sometimes they couldn't help but look at the light, even when asked to look away from it. As the age of the subjects increased, response times decreased and accuracy improved, peaking at age 20-25. As the subjects continued to age, the response times started to increase.

The researchers could also see which sections of the participant's brains were active, and which were less active, with age. With these baselines in place, the same experiments can now be conducted with patients who have ADHD and Parkinson's disease.

"In preliminary experiments, kids with ADHD could not help but look at the light no matter if they were asked to look away or not. Normal brain activity was also decreased," says Professor Munoz. "When they took their ADHD medication the success rates, and the activity in certain areas of the brain, increased. This test could therefore be used to examine the effectiveness of new ADHD medication."

The same holds true for Parkinson's disease. In preliminary experiments, patients with the disease had a consistent pattern of eye movement time and brain activity. Introducing the tests in clinics as part of regular health exams could result in earlier diagnosis of Parkinson's, allowing the disease progression to be controlled with diet and medication, Dr. Munoz adds.

Other members of the research team include, from Queen's, Drs. Giovanna Pari (Neurology), Angela Garcia (Geriatrics) and Patrick Stroman (Diagnostic Radiology); and Thomas Trappenberg, a computer scientist at Dalhousie University. The investigation into ADHD and Parkinson's disease will take place over the next five years, thanks to the $953,000 funding grant from CIHR.


'/>"/>

Contact: Jeff Drake
jeff.drake@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert

Related medicine news :

1. Life and Legacy of Philanthropist Theresa Lang Remembered at New York Hospital Queens Gala
2. Urban Health Plan Receives $1.3M from Economic Stimulus Package to Increase Health Care Access in Corona, Queens
3. Its a Wrap - New York Hospital Queens Goes Red Seven Stories Up to Build Awareness of Womens Risk for Heart Disease
4. Gold Coast, Queensland Cosmetic Plastic Surgeon Using Video to Give Virtual Tours of his Practice
5. For Second Consecutive Year New York Hospital Queens Named 100 Top Hospital Performance Improvement Leader
6. Queensland researchers get the latest tools to fight cancer
7. Keane Wins Revenue Cycle Management Implementation With Mount Sinai Hospital of Queens
8. Queensland technology licensed by billion-dollar US company
9. QueensLander Tours Presents an Adventure Boot Camp Cruise with John Spencer Ellis from Bravos The Real Housewives of Orange County
10. Queensland businessman is one in a million
11. Sudden Cardiac Arrest Association Launches Long Island and Queens Chapters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... 27, 2016 , ... More than a third of American adults are considered ... surgery has received increased attention in recent years, as an article published ... weight loss, most people are familiar with the basic requirements of maintaining a healthy ...
(Date:5/27/2016)... York, NY (PRWEB) , ... May 27, 2016 , ... ... campaign returns for a third time to shed lights on the variety of topics ... and inspirational stories, “Nurse Appreciation” tackles why this career has gone from being in ...
(Date:5/27/2016)... ... May 27, 2016 , ... In ... the many who are unaware of the plight of aphasia. In collaboration with ... the “Stroke Awareness” campaign. , The link between stroke and aphasia is relatively ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... in scholarships to students studying complementary medicine. Allison Outerbridge is this year’s ... her award on May 18 at the university’s Student Leadership Awards ceremony. , ...
(Date:5/26/2016)... , ... May 26, 2016 , ... W.S. Badger ... has been honored with a 2016 When Work Works Award for its use of ... of the national When Work Works project administered by the Families and Work Institute ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)...   , Study met ... bowel cleansing and superiority in , ... of the ascending colon   ... Norgine B.V. today announced new positive data from the phase ... preparation) versus standard 2 litre PEG with ascorbate. The study met ...
(Date:5/24/2016)... May 24, 2016  NxStage Medical, Inc. (Nasdaq: ... on advancing renal care, today announced that Jeffrey ... in the following schedule of investor conferences. Where applicable, ... at http://ir.nxstage.com/ .   ... Conference NY, NY           Friday, June 10, 2016 1:30 ...
(Date:5/24/2016)... HONG KONG , May 24, 2016 ... , the world , s ... and AV fistula intervention   OrbusNeich, a ... solutions, has expanded its portfolio to include products to ... balloons are the company,s first entry devices for lower ...
Breaking Medicine Technology: