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Quark Pharmaceuticals to Participate in IBC's Oligonucleotide Therapeutics: From Concept to Implementation Conference
Date:8/3/2009

p>Daniel Zurr, Ph.D., President and Chief Executive Officer of Quark, said, "Dr. Thompson's active and visible roles at the conference represent Quark's leadership position in the RNAi industry as the pioneer in systemic siRNA administration. We are at the forefront in oligonucleotide therapeutic development and look forward to discussing practical strategies and forward-looking approaches to support the current momentum in research and development in the field."

Dr. Thompson has been a leader in siRNA development for several years. Prior to joining Quark, he was Director of Research and Development at Genta, and previously Director of Biology Research at Sirna Therapeutics (formerly named Ribozyme Pharmaceuticals), which was acquired by Merck.

About Quark Pharmaceuticals, Inc.

Quark Pharmaceuticals, Inc. is a development-stage pharmaceutical company engaged in discovering and developing novel RNAi-based therapeutics. Quark has a fully integrated drug development platform that spans therapeutic target identification to drug development. Quark's RNAi technology includes novel siRNA structures and chemistry providing Quark with freedom to operate in the siRNA intellectual property arena, as well as the ability for non-invasive delivery of siRNA to other target tissues including the eye, ear, lung, spinal cord and brain.

PF-4523655 (RTP801i-14), currently in Phase II clinical trials, is a synthetic, chemically modified siRNA designed to inhibit the expression of the gene RTP801 discovered by Quark through the gene discovery platform BiFAR. PF-4523655 is licensed to Pfizer. In addition, Quark's current clinical pipeline includes QPI-1002, the first systemically administered siRNA drug in human clinical trials, developed by Quark for the prevention of acute kidney injury (AKI) following major cardiovascular surgery and the prophylaxis of delayed graft function after kidney transplantation
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SOURCE Quark Pharmaceuticals, Inc.
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