Navigation Links
Quark Pharmaceuticals Presents Data on Synthetic siRNAs for Prevention of Ocular and Inner Ear Sensory Cell Damage
Date:5/14/2009

FREMONT, Calif., May 14 /PRNewswire/ -- Quark Pharmaceuticals, Inc., a development-stage pharmaceutical company discovering and developing novel RNA interference (RNAi)-based therapeutics, today announced that Elena Feinstein, M.D., Ph.D., Chief Scientific Officer, presented a study titled, "siRNA Therapeutics for Prevention of Ocular and Inner Ear Sensory Cells Death," at the DxRx Summit: Nucleic Acid Diagnostics & Therapeutics. The event was held May 12-13, 2009 in Boston, MA.

Dr. Feinstein presented data demonstrating that synthetic, chemically-modified 19-bp siRNAs, including PF 04523655 currently being studied by partners Pfizer and Quark in patients with diabetic macular edema (DME) and age-related macular degeneration (AMD), enter cells in the retina of the eye and exert their therapeutic effects while avoiding non-specific activation of the toll-like receptor 3 (TLR3) - the effect reported for other synthetic siRNAs. Similar data for QPI-1007, Quark's proprietary siRNA composition, were also reported. QPI-1007 was demonstrated to confer effective ocular neuroprotection and is currently in late-stage IND-enabling studies.

In addition to studies in the eye, Dr. Feinstein also reported results demonstrating effective delivery of synthetic siRNAs to the inner ear, which resulted in protection of hearing epithelium from ototoxic and noise-induced damage. These studies were performed in collaboration with Prof. Jayakrishna Ambati, University of Kentucky College of Medicine, Lexington, KY; Prof. Ann Logan, University of Birmingham, UK; Prof. Adriana Di Polo, University of Montreal; and Prof. Richard Salvi, SUNY University at Buffalo.

Daniel Zurr, Ph.D., President and Chief Executive Officer, said, "Results from the studies presented at DxRx demonstrate our successful track record in discovering and advancing industry-leading siRNA product candidates. Our strong position
'/>"/>

SOURCE Quark Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Quark Pharmaceuticals to Present at the 20th Annual Piper Jaffray Health Care Conference
2. Quark Pharmaceuticals Receives FDA Approval of IND for Kidney Transplant siRNA Drug DGFi
3. Keryx Biopharmaceuticals, Inc. Announces First Quarter 2009 Financial Results
4. Transcept Pharmaceuticals Reports First Quarter 2009 Financial Results
5. MAP Pharmaceuticals to Present at the Deutsche Bank Securities 34th Annual Health Care Conference
6. Jiangbo Pharmaceuticals, Inc. Announces Conference Call to Discuss Results for its Third Quarter of FY 2009
7. Celator(R) Pharmaceuticals to Present at 2009 BIO International Convention
8. Arena Pharmaceuticals to Present at the 34th Annual Deutsche Bank Health Care Conference
9. Onyx Pharmaceuticals to Present at the Deutsche Bank 34th Annual Health Care Conference
10. Jiangbo Pharmaceuticals, Inc. to Present at CCG IRs China Rising Conference in New York
11. Vion Pharmaceuticals Reports 2009 First Quarter Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... April 17, 2015 Florida Hospital Wesley ... and Florida Hospital Carrollwood were all selected as Top ... located in Pasco County, is ranked number one for ... survey, which was conducted in partnership with an independent ... all-private bed hospital that opened in October of 2012 ...
(Date:4/17/2015)... 17, 2015 Consumers who prefer to ... modifications can now use the Insurance Pros USA website ... policy rates that are featured by leading companies quoting ... that are offered are mixed between three of the ... 79. There are now term, universal and whole policies ...
(Date:4/17/2015)... April 17, 2015 At the end ... Lounge and the “Salute to the Oscars” in the ... Hilton Hotel, overlooking the impressive Los Angeles skyline. These ... by Debbie Durkin, LA’s leading producer of sustainable product ... of the world’s premier providers of eco-friendly and socially ...
(Date:4/17/2015)... Organic Valley, the nation’s largest cooperative of ... Year of Soils by “Cycling for Sustainability” through California ... will travel 215 miles from Auburn, California, to the ... the impact of agriculture on water and soil in ... Wisconsin, Oregon, and Washington state, the cyclists have diverse ...
(Date:4/17/2015)... Calvary Hospital recently announced Timothy P. Barr will be ... May 11. The Fund directs all fundraising efforts in support ... J. Spinelli, who retired several months ago. , “We are ... the important work that the Fund does every year,” said ... expand and bring our signature care to people who need ...
Breaking Medicine News(10 mins):Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4Health News:General Life Insurance Policy Rates Added to Quotation System at Insurance Website Online 2Health News:Choices Recovery Speaks with Dakota Hood of “The Hunger Games” about Addiction in Hollywood 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 2Health News:Organic Valley Farmers and Employees "Cycling for Sustainability" Through 215 Miles of California Watershed April 19-25 3Health News:Timothy P. Barr Appointed Executive Vice President of Calvary Fund 2Health News:Timothy P. Barr Appointed Executive Vice President of Calvary Fund 3
... Heart attack patients whose blood potassium levels are within a ... levels of the mineral below or above that range, says ... in heart attack patients. Researchers looked at data from ... between 2000 and 2008. Of those patients, nearly 7 percent ...
... A new classification for diagnosing fibrosis in patients with ... as accurate as currently used algorithms, but required no ... issue of Hepatology , a journal published by ... Study of Liver Diseases, details a method that synchronously ...
... 10 (HealthDay News) -- People who suffer sudden cardiac arrest ... help bystanders assess victims and begin CPR immediately, says a ... of its main goals is to increase how often bystanders ... to arms," statement lead author E. Brooke Lerner, an associate ...
... January 10, 2012. Kessler Foundation and the University ... will collaborate on clinical research projects applying virtual ... The goal, according to USC,s Albert Rizzo, PhD ... is to conduct research to develop the evidence ...
... CHICAGO (January 10, 2012) According to the results ... issue of the Journal of the American College ... knowledge about their disease and were not meaningfully involved ... approach to treatment. As a result, the study,s investigators ...
... an up-close look at multimorbidity, the coexistence of multiple chronic ... growing at an alarming rate and bankrupting the U.S. health ... percent of the American population will be living with multiple ... $1.07 trillion. In fact, more than three-fifths of health care ...
Cached Medicine News:Health News:Study Challenges Potassium Guidelines for Heart Attack Patients 2Health News:New fibrosis classification improves accuracy of diagnosis in hepatitis C 2Health News:Heart Experts Make Boosting Bystander CPR a Priority 2Health News:Kessler Foundation and USC collaborate on clinical virtual reality for disability research 2Health News:Early-stage breast cancer patients lack knowledge; may not receive treatment they prefer 2Health News:Early-stage breast cancer patients lack knowledge; may not receive treatment they prefer 3Health News:January/February 2012 Annals of Family Medicine 2Health News:January/February 2012 Annals of Family Medicine 3Health News:January/February 2012 Annals of Family Medicine 4Health News:January/February 2012 Annals of Family Medicine 5Health News:January/February 2012 Annals of Family Medicine 6Health News:January/February 2012 Annals of Family Medicine 7Health News:January/February 2012 Annals of Family Medicine 8Health News:January/February 2012 Annals of Family Medicine 9
(Date:4/17/2015)... 17, 2015   IBA Molecular, a global ... today that it has signed a definitive agreement to ... (IBAM NA), to Illinois Health and Science (IHS). Under IHS ... independent company headquartered in Dulles, Virginia ... of new product and footprint synergies. IBA Molecular is ...
(Date:4/17/2015)... ADELAIDE, Australia , April 17, 2015 ... the discovery and development of innovative therapeutics for the ... system, today announced the presentation of data from three ... American Association for Cancer Research (AACR) 106 th ... Philadelphia, PA USA. ...
(Date:4/16/2015)... drug commonly taken to prevent seizures in epilepsy may surprisingly ... to a study released today that will be presented at ... Washington, DC , April 18 to 25, 2015. ... at some point in their life a condition called acute ... eye to the brain gets inflamed," said study author Raj ...
Breaking Medicine Technology:Health Care System to Acquire IBA Molecular North America 2Health Care System to Acquire IBA Molecular North America 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 2Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 3Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 4Bionomics Showcases Oncology Drug Development Programs at 2015 AACR Annual Meeting 5Epilepsy Drug May Preserve Eyesight for People with MS 2
... , SANTA MONICA, Calif. and ... QUOSA, Inc., today announced that Cubist Pharmaceuticals ... between Reprints Desk,s STM Document Delivery service with QUOSA,s ... literature re-use. The integrated solution features integration with ...
... , SOUTH SAN FRANCISCO, Calif., Dec. 9 Anesiva, ... 3, 2009, Anesiva entered into an Asset Purchase Agreement which ... Technologies, Ltd., dated November 30, 2009, and sold certain assets ... British Virgin Island LLC, and Lee,s Pharmaceuticals (HK) Limited (Lee,s ...
Cached Medicine Technology:Cubist Pharmaceuticals Becomes First Company to Implement Integrated Reprints Desk Document Delivery and QUOSA Scientific Literature Workflow Solution 2Cubist Pharmaceuticals Becomes First Company to Implement Integrated Reprints Desk Document Delivery and QUOSA Scientific Literature Workflow Solution 3Anesiva Completes Sale of its Zingo(TM) Assets to Powder Pharmaceuticals and Lee's Pharmaceuticals 2
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
The Snap-In Snap-Out-II Tip Inserts offer a large variety of configurations....
Medicine Products: