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Quality of life benefits of transcatheter aortic valve replacement differ by access site
Date:11/10/2011

measures. For TF patients, TAVR resulted in substantial quality of life benefits compared with surgical AVR at one month with similar benefits at later time points. For patients eligible only for the TA approach, there was no benefit of TAVR over AVR at any time point, and quality of life measures tended to be better with surgical AVR at both one and six months.

"Taken together with previous data, these findings demonstrate that for patients suitable for a transfemoral approach, transcatheter aortic valve replacement provides meaningful clinical benefits compared with surgical aortic valve replacement from the patient's perspective," said David J. Cohen, MD, the principal investigator for the quality of life sub-study. Dr. Cohen is Professor of Medicine at the University of Missouri-Kansas City and Director of Cardiovascular Research at Saint Luke's Mid America Heart Institute.

"The lack of benefit and suggestion of worse outcomes among patients ineligible for the transfemoral approach suggest that the transapical approach may not be preferable to surgical aortic valve replacement in such patients. Whether further experience and refinements in the transapical approach can overcome these limitations should be the subject of future investigation."


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Contact: Judy Romero
jromero@crf.org
Cardiovascular Research Foundation
Source:Eurekalert

Page: 1 2

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