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Quality of Life an Issue in Prostate Cancer Treatment
Date:3/19/2008

Each therapy has an impact on overall day-to-day living, experts say

WEDNESDAY, March 19 (HealthDay News) -- Quality-of-life issues should be weighed carefully when prostate cancer patients are considering the thicket of treatment options available to them, new research suggests.

Different therapies can have a very different impact on aspects of everyday living, and these outcomes need to be discussed with the doctor, the patient and his spouse or partner, concludes a study appearing in the March 20 issue of the New England Journal of Medicine.

"Every patient has to weigh their hope, fears, concerns and expectations against the risks and benefits and include their spouse in the decision-making," said Dr. Jeff Michalski, co-author of the paper and a radiation oncology professor at Washington University School of Medicine in St. Louis. "You can't expect one size to fit all. Patients are often faced with decisions based on quality-of-life impact."

"With cancer treatment, it's not enough just to be a survivor, particularly with prostate cancer," added Dr. David Chen, attending surgeon with Fox Chase Cancer Center in Philadelphia, who was not involved with the study. "The majority of patients are asymptomatic [after treatment], so their quality of life becomes very important. A paper like this is important to show some of those effects in a quantified way."

Prostate cancer can be successfully treated in a number of ways, notably with a radical prostatectomy, which is surgery to remove the prostate and some surrounding tissue, or with external-beam radiation therapy, or with brachytherapy, in which radioactive "seeds" are implanted in the tumor.

"There are no randomized trials between the three modalities," Michalski noted. "No one is better than the others."

The researchers, from nine hospitals, looked at quality-of-life data on 1,201 patients and 625 spouses or partners b
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