Navigation Links
QLT announces interim data from a Phase II clinical trial and a device study for the Punctal Plug Drug Delivery System
Date:7/28/2009

uates the effect of artificial tears preserved with benzalkonium chloride (AT-BAK) on IOP response to L-PPDS; 22 patients are currently enrolled and enrollment is continuing. The second trial compares IOP and safety outcomes based on L-PPDS placement (upper or lower punctum); enrollment is complete with 30 patients, and follow-up is ongoing.

The Device Study (Punctal Plug Prototype Designs)

This study is an ongoing, device, open-label, multicenter study conducted to investigate the safety, tolerability, comfort, ease of handling and insertion/removal, and retention of punctal plug prototype designs, in healthy subjects. Subjects are fitted with a punctal plug in each eye and wear the devices for 24 hours, after which the plugs are removed and replaced. Subjects then wear the devices for up to 12 weeks. Enrollment is ongoing. The preliminary overall retention rate of 75% after eight weeks of follow-up is based on a baseline sample of 447 eyes from 239 subjects who were fitted with prototypes from one family of designs. Subject comfort ratings for this design family are high (mean of 97 on a scale of 0-100 at Week 8), and physician handling assessments indicate that the devices are easy to insert and remove. Interim analyses show that these designs have been well tolerated. The most frequently reported adverse events for subjects fit with this family of designs have been increased lacrimation, eye irritation, and device migration (2.1% for each event); conjunctival hyperemia (1.7%); and conjunctival edema and eye disorder (1.3% for each event). Interim analyses of all punctal plug prototype designs in 590 subjects show that the most frequently reported adverse events overall have been device migration (3.7%), conjunctival hyperemia (1.3%), and eye irritation (1.0%).

Prototype punctal plug designs continue to be refined and evaluated to meet our retention criteria and converge with the identification of a dose formulation to pr
'/>"/>

SOURCE QLT Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. QLT Announces Second Quarter Results for 2009
2. MoviMED Announces Participation in NIWeek 2009 Conference to Examine Trends and Technologies for Boosting Productivity and Increasing Competitive Advantage
3. Grupo Casa Saba Announces Quarterly Earnings Report 2Q09
4. Image Sensors 2009 Announces Final Program and New Interactive Brochure
5. ULURU Inc. Announces Status of York Note Receivable
6. Danaher Corporation Announces Retirement of Executive Vice President Philip W. Knisely
7. Paradigm Spine Closes $21.5 Million Financing and Announces Promotion of Matt Stuttle to Position of Vice President, US Sales
8. Electronic Healthcare Network Announces Multi-State Expansion, Beginning in Buffalo, NY
9. Association of Gaming Equipment Manufacturers (AGEM) Announces $100,000 in Contributions to Organizations Working to Assist Problem Gamblers
10. American DG Energy Announces $3.5 Million Private Placement
11. Brookdale Announces Second Quarter 2009 Release and Earnings Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2014)... Global electrophysiology devices market is ... according to a new study by Grand View ... clubbed with growing global geriatric population base are ... in the budding stage, the electrophysiology devices market ... in the recent times, with physicians increasingly gaining ...
(Date:11/24/2014)... A new sports massage technique available ... and massage therapy provider, announced it newest massage ... newest sports massage is a fast-acting, “to-the-point” ... sports massage and ESM is that ESM has ... "reset button,” and ESM can increase flexibility, elasticity, ...
(Date:11/24/2014)... Mental health issues affect tens ... up families, ruin careers, and generally destroy lives. ... that suffer,” says Hardy Nutritionals® founder ... our specialized nutritional treatments can reverse these disorders ... Over Matter”, the premiere episode of O2 Media’s ...
(Date:11/24/2014)... Dr. Michael Kettel , a leading ... on NBC to discuss egg freezing as a viable and ... in the news recently, with new company benefits at Facebook ... , “[The companies] see it as a way to ... hot path.” Says Dr. Kettel. , Up until a few ...
(Date:11/23/2014)... The report, “Market Snapshot: Aesthetic ... - Asia-Pacific” provides quantitative analysis of the three ... invasive body contouring devices, non-invasive body contouring devices ... size data by revenue and volume over the ... Japan, South Korea, Australia and India. It uses ...
Breaking Medicine News(10 mins):Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 2Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 3Health News:Electrophysiology Devices Market Worth Forecasted To Reach $6.19 Billion By 2020: Grand View Research, Inc. 4Health News:Sports Massage in London by Massaggi Presents New Technique to Reset Muscles, Rapidly Eliminate Pain 2Health News:Sports Massage in London by Massaggi Presents New Technique to Reset Muscles, Rapidly Eliminate Pain 3Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 2Health News:Nutritional Mental Health Treatment Featured on Access Health Airing on Lifetime Television® 3Health News:Dr. Michael Kettel of San Diego Fertility Center Gives “An Inside Look at Freezing Eggs” on NBC 2Health News:Dr. Michael Kettel of San Diego Fertility Center Gives “An Inside Look at Freezing Eggs” on NBC 3Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 2Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 3Health News:Aesthetic Lasers and Energy Devices Market in APAC (China, Japan, South Korea, Australia and India) to 2020 4
... and more drug advertisements are appearing on television, ... that pharmaceutical companies spend annually to market their ... (residents) and medical students. , A literature ... of Medicine and the Regenstrief Institute, Inc. published ...
... suggests it boosts production of bone-eroding cells , , MONDAY, Dec. ... millions of diabetes patients, may contribute to bone loss, according ... that, over the long term, Avandia (rosiglitazone) may speed osteoporosis, ... and even fatal fractures. , The findings appear in the ...
... Hurricane Katrina was one of the,five deadliest ... costliest (at an,estimated $86 billion.) The total fatalities ... Witnessing the,destruction/displacement from the West Coast, CJ (of ... new school training techniques, with,old school parental inspirations, ...
... fake snow can trigger symptoms, experts warn , SATURDAY, Dec. ... to become the season of sneezing, congestion and other ... say experts at the American Academy of Allergy, Asthma & ... to a minimum, they say. , "Whether it,s feasting on ...
... annual,Saddleback Global Summit on AIDS & The Church concluded yesterday ... more than 1,700 attendees for,the Church to lead with love ... need to have the invisible God made visible to,them -- ... things we,don,t know about this epidemic, but what we do ...
... A recent press release,incorrectly attributed findings from an ... of family caregivers. Today,SarahCare issued the following statement ... release issued by SarahCare corporate did not attribute,data ... the "Evercare(R)/NAC,Study of Caregivers -- What They Spend, ...
Cached Medicine News:Health News:Do medical schools affect the way future doctors interact with drug companies? 2Health News:Diabetes Drug Avandia Could Weaken Bones 2Health News:CJ Transforms His Functional Fitness Program Into an Additional Resource for the Hurricane Katrina Survivors 2Health News:CJ Transforms His Functional Fitness Program Into an Additional Resource for the Hurricane Katrina Survivors 3Health News:'Tis the Season For Allergy, Asthma 2Health News:Global Summit on AIDS & The Church Calls for Public, Private and Parish Sectors To Unite in Response to Worldwide Pandemic: Pastor Rick and Kay Warren Host More Than 1,700 at Event Featuring International Dignitaries, Political Figures and International E 2Health News:Global Summit on AIDS & The Church Calls for Public, Private and Parish Sectors To Unite in Response to Worldwide Pandemic: Pastor Rick and Kay Warren Host More Than 1,700 at Event Featuring International Dignitaries, Political Figures and International E 3
(Date:11/21/2014)... , Nov. 21, 2014  World Hemp Oil, ... low THC, announces they are now offering legal, organic ... Charlotte,s Web type strains grown in medical marijuana states. ... neurological disorders, such as Parkinson,s, MS, and spinal cord ... laws to pass, because imported CBD Oil Is legal ...
(Date:11/21/2014)... Nov. 21, 2014  Abaxis, Inc. (NasdaqGS: ... and consumables for the medical, research, and veterinary markets ... and research markets in the United States ... purchase agreement to acquire 100% of QCR & Trio ... based distribution organization. The transaction closed on November 17, ...
(Date:11/21/2014)... MONTREAL , 21. November 2014 ... hat heute bekannt gegeben, dass ... – EMA) die Kennzeichnung als Orphan-Medizinprodukt ... Produktkandidat des Unternehmens zur Behandlung von ... eine seltene, stark beeinträchtigende genetische Krankheit, ...
Breaking Medicine Technology:New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 2New CBD Oil From Industrial Hemp is Comparable to Charlotte's Web, Legal In All 50 States 3Abaxis Acquires UK-based Distribution Organization 2Abaxis Acquires UK-based Distribution Organization 3Abaxis Acquires UK-based Distribution Organization 4Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 2Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 3
... June 21, 2011 Robbins & Myers, Inc. (NYSE: ... of Directors has approved its regular quarterly cash dividend ... on August 5, 2011 to shareholders of record as ... Inc. is a leading supplier of engineered equipment and ...
... 2011 Reportlinker.com announces that a new market ... The Outlook for Medical Devices in ... Detailed analysis of four ... global medical device market and which present immense ...
Cached Medicine Technology:Reportlinker Adds The Outlook for Medical Devices in North East Asia 2Reportlinker Adds The Outlook for Medical Devices in North East Asia 3Reportlinker Adds The Outlook for Medical Devices in North East Asia 4
... single-use is designed to saturate dry eyes, ... very dry eyes. For maximum hydration and ... dosing--splitting the entire contents of one container, ... after opening at least 4 times a ...
POLYSORB™ sutures are composed of LACTOMER™ glycolide/lactide copolymer which is a synthetic polyester composed of glycolide and lactide (derived from glycolic and lactic acids)....
Surgitie&trade Single Use Ligating Loops with Delivery System...
Surgitie&trade Single Use Ligating Loops without Delivery System with POLYSORB™....
Medicine Products: