Navigation Links
QLT announces interim data from a Phase II clinical trial and a device study for the Punctal Plug Drug Delivery System
Date:7/28/2009

g L-PPDS is roughly equivalent to 54 latanoprost eye drops, or about 60% of the amount of drug in eye drops given continuously over three months.

Concurrent with the Phase II clinical trial, punctal plug prototype designs for the sustained delivery system are being tested in an ongoing multicenter study in more than 500 healthy volunteers. Safety, tolerability, comfort, ease of handling and insertion/removal, and retention are being assessed in this study. The overall goal for development is to achieve 90% retention for 90 days. Based on currently available data, preliminary results for one family of designs show an overall retention rate of 75% after eight weeks of follow-up. While this does not yet meet the Company's retention criteria, designs are continuing to be refined and evaluated, with longer-term follow-up on the improved designs anticipated by year-end.

"We are pleased with the progress of our Phase II clinical trial and device program," said Bob Butchofsky, President and Chief Executive Officer of QLT. "The interim data we announced today are encouraging and are in line with the data we reported from our earlier CORE study. The results observed at Week 4 are clinically meaningful and similar to the IOP decrease we saw in the CORE study at the same time point. We believe there is sufficient room to increase the dose of latanoprost to further increase reduction in IOP while maintaining a favorable safety profile, and we look forward to updating you on the clinical progress of our higher dose evaluations. We continue to refine our designs for punctal plugs and anticipate that these will lead to improved retention rates in ongoing clinical trials."

The 44-(micro)g Phase II Study

This study includes two cohorts and is an ongoing, Phase II, open-label, multicenter study conducted to investigate the safety and preliminary efficacy of L-PPDS containing either 44-(micro)g (first cohort) or 81-(micro)g (second coho
'/>"/>

SOURCE QLT Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. QLT Announces Second Quarter Results for 2009
2. MoviMED Announces Participation in NIWeek 2009 Conference to Examine Trends and Technologies for Boosting Productivity and Increasing Competitive Advantage
3. Grupo Casa Saba Announces Quarterly Earnings Report 2Q09
4. Image Sensors 2009 Announces Final Program and New Interactive Brochure
5. ULURU Inc. Announces Status of York Note Receivable
6. Danaher Corporation Announces Retirement of Executive Vice President Philip W. Knisely
7. Paradigm Spine Closes $21.5 Million Financing and Announces Promotion of Matt Stuttle to Position of Vice President, US Sales
8. Electronic Healthcare Network Announces Multi-State Expansion, Beginning in Buffalo, NY
9. Association of Gaming Equipment Manufacturers (AGEM) Announces $100,000 in Contributions to Organizations Working to Assist Problem Gamblers
10. American DG Energy Announces $3.5 Million Private Placement
11. Brookdale Announces Second Quarter 2009 Release and Earnings Call
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Steven Reinberg HealthDay Reporter ... sign that the Ebola outbreak in West Africa is starting to ... more than 700 new cases of the deadly viral infection were ... of cases to more than 5,300, with roughly half of those ... reported. The number of deaths now tops 2,600. WHO has ...
(Date:9/18/2014)... 2014 Companies in the Carbon ... selling it to downstream industries in either gas, liquid ... are food and beverage manufacturers. Food producers use carbon ... or pizzas. The gas is also used as a ... to carbonate soft drinks, beer and other beverages. According ...
(Date:9/18/2014)... study has proven it true: exercise is good for ... suggests that exercise may have an added benefit for ... a mouse model of melanoma, found that combining exercise ... , Joseph Libonati, an associate professor in the School ... and Translational Nursing Research, was the senior author on ...
(Date:9/18/2014)... Qualis Health, one of the nation’s ... white paper, “Advancing Primary Care through the Patient-Centered Medical ... , Authors Jeff Hummel, MD, MPH and Peggy C. ... engaged in the work of becoming a Patient-Centered Medical ... PCMH objectives, such as generating and providing useful data ...
(Date:9/18/2014)... Non-governmental stakeholders will convene a one-day conference at the ... Washington University on September 25, 2014 to discuss the ... GHSA implementation. The purpose of this event is to ... the next five years, including action plans to curtail ... launch of the GHSA, international organizations and more than ...
Breaking Medicine News(10 mins):Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 2Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 3Health News:Carbon Dioxide Production in the US Industry Market Research Report Now Available from IBISWorld 2Health News:Carbon Dioxide Production in the US Industry Market Research Report Now Available from IBISWorld 3Health News:Exercise boosts tumor-fighting ability of chemotherapy, Penn team finds 2Health News:Advancing Primary Care Through PCMH and HIT: New White Paper Connects the Dots 2Health News:Non-governmental stakeholders to discuss the Global Health Security Agenda 2
... student in Orissa's Bhadrak district now has hopes of pursuing ... struggle to secure a study loan. ,Imran Alli, ... in his graduation in social work. He managed to get ... Science here to pursue postgraduate studies. ,Alli, the ...
... finds that by tailoring the intensity of radiation to ... chemotherapy improves outcome for those// suffering medulloblastoma. ... Children’s Research Hospital has announced that improved treatment measures ... rate of survival of children with this disease. , ...
... to be inhabited by a rather peculiar protein, sobriquet as ... pattern which is exactly the opposite of the code present ... the theory prescribed in the molecular biology textbooks. ... thinking that relied on the information that the structure of ...
... help in the eventually help in the treatment of ... the Oregon Health & Science University have succeeded in ... a genes over-expression causes skin stem cells to change ... ,The results of the discovery by the ...
... the hardness or elasticity of the liver has been ... (MRI).// Initial tests show promise for this technology, MR ... that can lead to incurable cirrhosis if not treated ... diagnosed using needle biopsies, which can involve complications and ...
... with chemotherapy-induced anemia and anemia associated with chronic ... Amgen's Aranesp, //which is a prefilled autoinjector. The ... States., ,"With the availability of the Aranesp ... have a new secure and simple option that ...
Cached Medicine News:Health News:Survival rates improve with better treatment options for medulloblastoma 2Health News:Survival rates improve with better treatment options for medulloblastoma 3Health News:Discovery of A New Genetic Pathway Could Lead To Treatment Of Skin Problems And Cancer 2Health News:MRI Development Yields Breakthrough in Diagnosis of Liver Fibrosis 2Health News:Amgen introduces Autoinjector For Treating Anemia 2Health News:Amgen introduces Autoinjector For Treating Anemia 3Health News:Amgen introduces Autoinjector For Treating Anemia 4
(Date:9/18/2014)... --  3D Systems   (NYSE: DDD ) announced ... a new robotic surgery skills and procedural training simulator, which ... exhibition in Amsterdam, The Netherlands from ... invasive surgery represents a growing portion of overall surgical volume, ... robotic surgery has increased, and it is expected that this ...
(Date:9/18/2014)... 18, 2014  Neurotrope, Inc. (OTCQB: NTRP) today announced ... Ph.D. to the Company,s Board of Directors, effective September ... vacancy on the Board of seven members. Dr. Altstiel ... Governance Committee and a member of the Audit and ... of Neurotrope,s Scientific Advisory Board, a position he has ...
(Date:9/18/2014)... Australian biomarker discovery company Minomic International Ltd will today ... cancer screening test, planning to achieve US Food and ... Minomic,s proprietary MiStat™ technology is a screening assay capable ... as the MIL-38 antigen. This biomarker is present on ... Researchers at 11 leading urology centres in ...
Breaking Medicine Technology:3D Systems Introduces New Simbionix Robotics Training Platform 23D Systems Introduces New Simbionix Robotics Training Platform 3Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 2Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 3Larry D. Altstiel, M.D., Ph.D. Joins Neurotrope Board of Directors 4Minomic Launches US Pilot Study of MiStat(TM) Novel Prostate Cancer Screening Technology 2
... Pa., Jan. 12, 2011 ECRI Institute® ( ... the best approaches to improving patient care, is ... Health Devices Achievement Award program. The award ... technology management. (Logo: http://photos.prnewswire.com/prnh/20110112/DC29081LOGO ...
... 2011, what will be the major trends in the ... regulations affect what,s next and what,s new?  What will ... competitive corporate landscape?  When it comes to market research, ... the job done right? The answers to these questions ...
Cached Medicine Technology:ECRI Institute's 2011 Health Devices Achievement Award - Call for Entries 2ECRI Institute's 2011 Health Devices Achievement Award - Call for Entries 3Pharma Industry Leaders to Reveal Hottest, Latest Trends for Pharma & Biotech at Groundbreaking Event 2
The CryoSurgery console is the control center for CryoCath's surgical probe. It is a modular system made up of a console control unit and a tank dolly system. The system can be used as a unit or in s...
... developed a minimally invasive cryocatheter to ... delivers a very high level of ... site precision, minimal tissue disruption, and ... ,Freezor is a flexible, single-use, minimally ...
The Valve Mapper Steerocath-Dx has a unique "peanut" shaped tip. It is designed to conform to the anatomy during mapping procedures. Both 8F/8mm and 8F/6mm tips are available....
... The PORTERFIELD catheter incorporates six electrodes which ... from a single catheter. Positioned in the ... while recording atrial electrograms. The catheter may ... apex for atrial recording and ventricular pacing ...
Medicine Products: