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QED International Associates Announces Changes to the HealthShares(TM) Composite, HealthShares(TM) Cardio Devices, and the HealthShares(TM) Orthopedic Repair Indexes

NEW YORK, Nov. 5 /PRNewswire/ -- QED International Associates Inc, administrator for the HealthShares(TM) Exchange-Traded Funds, a series of 20 underlying fund portfolios, today announced that effective at the opening of trading on Wednesday November 7, 2007 BioSphere Medical Inc. (Nasdaq: BSMD) will replace Kyphon INC. (Nasdaq: KYPH), in the HealthShares(TM) Cardio Devices Index, The Corin Group (LSE: CRG.L) will replace KYPH in the HealthShares(TM) Orthopedic Repair Index, and LiveCell Corp, (Nasdaq: LIFC) will replace KYPH in the HealthShares(TM) Composite Index. Kyphon is being acquired by Medtronic Inc (NYSE: MDT).

Companies included in the Cardio Devices Index engage in the manufacture, distribution, and commercialization of medical devices for the treatment of cardiac, vascular, and endovascular disorders and diseases, including but not limited to stents, valves, patches, pumps, defibrillators, pacemakers, sutures and sensors/ chips.

Companies included in the Orthopedic Repair Index are engaged in the manufacturing, distribution, and/or commercialization of medical devices, pharmaceuticals and/or regenerative medicine for the treatment of bone, cartilage, tendon, muscle, ligament, maxillofacial and dental elements, excluding periodontal and skin conditions or disorders.

About HealthShares(TM)

XShares Advisors LLC, a financial services company based in New York, is the creator of the HealthShares(TM) family of Exchange Traded Funds (ETFs). HealthShares(TM) ETFs are organized into therapeutic 'Verticals' and represent specific areas of the healthcare, life science and biotechnology industries. Each Vertical addresses a distinct sub-segment of healthcare, such as the diagnosis and treatment of specific therapeutic areas (e.g. cardiology, cancer, infectious disease, etc.) and the development of medical devices (e.g. orthopedic repair, cardio devices, etc.). Each ETF tracks an index of 22-25 stocks and offers institutional and individual investors a more precise financial instrument that leverages the potential of healthcare investing while mitigating the risks of single stock picking. For more information, visit the company's website at:

About XShares

XShares Advisors LLC, a subsidiary of XShares Group LLC, is a registered investment advisor that provides investment advisory services to Exchange Traded Funds. XShares also partners with major institutions and index providers seeking to bring innovative Exchange Traded Funds to market using its administrative platform. In addition, XShares creates and licenses distinctive intellectual property for its ETFs, developing products that allow for innovative trading strategies and alternative investments for the financial community. For more information, visit the company's website at

About QED International Associates

QEDI International, based in New York, is a leading financial industry consulting firm specializing in quantitative modeling and the design, development and maintenance of indexes and Exchange Traded Funds. For more information, visit the company's website at

SOURCE QED International Associates Inc
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