Navigation Links
QBI neuroscientists make Alzheimer's disease advance
Date:6/10/2008

Queensland Brain Institute (QBI) neuroscientists at UQ have discovered a new way to reduce neuronal loss in the brain of a person with Alzheimer's disease.

Memory loss in people with Alzheimer's disease can be attributed to several factors.

These include a build-up of the neuro-toxin Amyloid beta the major component of amyloid plaques found in patients with Alzheimer's and corresponding degeneration of a specific population of nerve cells in the basal forebrain.

QBI neuroscientist Dr Elizabeth Coulson's research was recently published in the Journal of Neuroscience.

She said the research had established that the molecule known as p75 neurotrophin receptor was necessary for the Amyloid beta to cause nerve cell degeneration in the basal forebrain.

During her research, Dr Coulson's team found both in cultured cells and in an animal model of Alzheimer's disease that it was possible to completely prevent Amyloid beta toxicity by removing the p75 cell death receptor.

"Discovering how Amyloid beta triggers neuronal degeneration has been a question bugging neuroscientists for decades, and we have identified an important piece of the puzzle," Dr Coulson said.

These results provide a novel mechanism to explain the early and characteristic loss of brain cells that occurs in Alzheimer's disease which are known to be important for memory formation.

Dr Coulson already has patented molecules that can block p75 and is ready to begin testing them in animal models of Alzheimer's disease.

"If such therapy is successful, it probably wouldn't cure this multifaceted disease," Dr Coulson said.

"But it would be a significant improvement on what is currently available for Alzheimer's disease patients."

The World Health Organisation predicts that by 2040, neurodegenerative conditions will become the world's leading cause of death, overtaking cancer.

Alzheim
'/>"/>

Contact: Dr. Elizabeth Coulson
communications@uq.edu.au
61-733-466-392
Research Australia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
2. Jefferson neuroscientists find early lead exposure impedes recovery from brain injury
3. Alzheimers Research Target May Be a Dead End
4. Smoking may strongly increase long-term risk of eye disease
5. Pot bellies linked to early signs of cardiovascular disease
6. Anemia and tropical diseases; Is pharmacogenomics ready for the clinic?
7. Radiologists encouraged to look beyond cancer for clinically unseen diseases
8. Use of certain lipid measures not more effective in predicting coronary heart disease
9. Role seen for cannabis in helping to alleviate allergic skin disease
10. New prion protein discovered by Canadian scientists may offer insight into mad cow disease
11. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... York (PRWEB) August 21, 2014 According ... Research "Medical Fiber Optics Market-Global Industry Analysis, Size, Share, ... medical fiber optics market was valued at USD 863.1 ... a CAGR of 7.6% from 2013 to 2019, to ... 2019. , The medical fiber optics market is witnessing ...
(Date:8/21/2014)... Maryland (PRWEB) August 21, 2014 ... with guidance from Lockton Companies and builds on ... industry’s only cellular glucometer, combined with Accountable Health’s ... robust data analytic capabilities and adds a custom ... care, including eye exams, provider visits, HbA1c testing ...
(Date:8/21/2014)... Aspen Advisors, a U.S.-based healthcare consulting firm, ... Modern Healthcare’s Best Places to Work in Healthcare ... healthcare industry for creating workplaces that enable employees to perform ... employee responses to an employee engagement and satisfaction survey. ... has been named a “Best Places to Work in Healthcare”. ...
(Date:8/21/2014)... on in the morning? Do we drive to work or ... to buy lunch? We make hundreds of different decisions every ... it is extremely important for our long-term personal development to ... ADHD often find this difficult, however. They are known to ... but smaller reward instead of making a choice that yields ...
(Date:8/21/2014)... August 21, 2014 Artisan Business Group ... Investment Exploratory Delegation to southern China October 12-19, 2014. ... explore the rapid growing cities of Shenzhen and Guangzhou. ... have the rare opportunity to meet with major Chinese ... a short weeklong time frame. , The trade ...
Breaking Medicine News(10 mins):Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 2Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 3Health News:Global Medical Fiber Optics Market: Industry Analysis, Size, Share, Growth, Trend and Forecast 2013 - 2019 4Health News:Accountable Health Expands Diabetes Management Solutions to Address Gaps in Provider Care 2Health News:Accountable Health Expands Diabetes Management Solutions to Address Gaps in Provider Care 3Health News:Modern Healthcare Names Aspen Advisors Among the Top 100 Employers in the Healthcare Industry for a Fourth Consecutive Year 2Health News:ADHD children make poor decisions due to less differentiated learning processes 2Health News:Artisan Business Group announces 2014 EB-5 Investment Trade Mission to China 2
... ... in Ophthalmology (JCAHPO), and the Association of Technical Personnel in Ophthalmology (ATPO) proudly launched ... Reference Guide for the Ophthalmic Technician. , ... St. Paul, MN (Vocus) November 10, 2009 -- Compact, ...
... HATBORO, Pa., Nov. 10 InfoLogix, Inc. (Nasdaq: ... solutions for the healthcare and commercial industries, today announced ... exception to NASDAQ,s stockholder approval requirements, in accordance with ... on this exception to complete a proposed plan of ...
... ... Arm in the Last 30 Years" , ... Gulf Breeze, Fla. (Vocus) November 10, 2009 -- The Andrews-Paulos Research & ... Rounds presentation on November, 19, 2009 at 5:30 p.m. (CT). Renowned orthopaedic and sports ...
... Better coordination urged to stem re-admission rate of nearly 1 ... Almost a quarter of the people on Medicare who are ... a month of discharge, a new study reveals. , That ... assistant professor of geriatrics and palliative medicine at the Mount ...
... YORK Medications frequently given to cancer patients to ... increased risk of deep vein thrombosis or pulmonary embolism, ... M.S., co-director of the breast cancer program at the ... Medical Center. The findings will be published online on ...
... Amalgamated Capital, a newly formed division of Amalgamated ... in the recapitalization of Oklahoma City-based 180 Medical, Inc., ... Amalgamated Capital provides senior cash flow debt financing to ... firms and other investors are financial sponsors. , 180 ...
Cached Medicine News:Health News:JCAHPO/ATPO Pocket Guide Launches for Eye Care Professionals 2Health News:JCAHPO/ATPO Pocket Guide Launches for Eye Care Professionals 3Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 2Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 3Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 4Health News:InfoLogix Announces Receipt of NASDAQ Waiver for Stockholder Approval of Restructuring and Extension to Stockholder's Equity Requirement 5Health News:Orthopaedic Surgeon and AOSSM President Dr. James Andrews to Discuss Injury Prevention 2Health News:Orthopaedic Surgeon and AOSSM President Dr. James Andrews to Discuss Injury Prevention 3Health News:The Revolving Door of Heart Failure Hospitalization 2Health News:The Revolving Door of Heart Failure Hospitalization 3Health News:Drugs to treat anemia in cancer patients linked to thromboembolism 2Health News:Drugs to treat anemia in cancer patients linked to thromboembolism 3Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 2Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 3Health News:Amalgamated Capital Serves as Syndication Agent in the Recapitalization of 180 Medical, Inc. 4
(Date:8/20/2014)... Aug. 20, 2014 Children aren,t the ... vaccinations to help prevent disease. The Centers for ... all adults, but currently, many adults are not ... National Immunization Awareness Month, and the American Lung ... especially those with lung disease, to talk with ...
(Date:8/20/2014)... , August 20, 2014 ... market report titled "Monochloroacetic Acid (MCA) Market for Cellulosics, ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast ... valued at USD 817.1 million in 2013 and is ... at a CAGR of 3.6% during the forecast period ...
(Date:8/20/2014)... 2014 Reportlinker.com announces that a ... its catalogue: Wireless Opportunities in ... UWB WWAN, WMAN, WLAN and other technologies) ... Kalorama Information,s Wireless Opportunities in Healthcare ... WWAN, WMAN, WLAN and other technologies) is ...
Breaking Medicine Technology:American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 2American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 3Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 2Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 3Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 4Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 2Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 3Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 4Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 5Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 6Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 7Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 8Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 9Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 10Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 11Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 12Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 13Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 14Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 15Wireless Opportunities in Healthcare (The Market for Bluetooth, RFID, Zigbee, UWB WWAN, WMAN, WLAN and other technologies) 16
... May 23, 2011 Reportlinker.com announces that ... in its catalogue: Advanced ... http://www.reportlinker.com/p0507254/Advanced-Digital-Medical-Equipment-Products-Market .html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Imaging ... sizes the advanced medical device markets, particularly ...
... 2011 Reportlinker.com announces that a ... in its catalogue: ... of Water and Wastewater Management in ... http://www.reportlinker.com/p0506839/Global-Water-Market-Outlook-Strategic-Analysis-of-Water-and-Wastewater-Management-in-the-Pharmaceutical-Industry.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Water_dis This ...
Cached Medicine Technology:Reportlinker Adds Advanced Digital Medical Equipment Products Market 2Reportlinker Adds Advanced Digital Medical Equipment Products Market 3Reportlinker Adds Advanced Digital Medical Equipment Products Market 4Reportlinker Adds Advanced Digital Medical Equipment Products Market 5Reportlinker Adds Advanced Digital Medical Equipment Products Market 6Reportlinker Adds Advanced Digital Medical Equipment Products Market 7Reportlinker Adds Advanced Digital Medical Equipment Products Market 8Reportlinker Adds Advanced Digital Medical Equipment Products Market 9Reportlinker Adds Advanced Digital Medical Equipment Products Market 10Reportlinker Adds Advanced Digital Medical Equipment Products Market 11Reportlinker Adds Advanced Digital Medical Equipment Products Market 12Reportlinker Adds Global Water Market Outlook: Strategic Analysis of Water and Wastewater Management in the Pharmaceutical Industry 2Reportlinker Adds Global Water Market Outlook: Strategic Analysis of Water and Wastewater Management in the Pharmaceutical Industry 3Reportlinker Adds Global Water Market Outlook: Strategic Analysis of Water and Wastewater Management in the Pharmaceutical Industry 4
... (IFA) test for the detection and semi-quantitation ... Louis Encephalitis virus (SLE), Western Equine Encephalitis ... and California Encephalitis/La Crosse virus (CE). Each ... individual spots of SLE, WEE, EEE, and ...
... Indirect immunofluorescent antibody (IFA) ... and semi-quantitation of human ... Epstein-Barr viral capsid antigen ... ten 12-well slides, FITC ...
... immunofluorescent (ACIF) antibody test ... semi-quantitation of human serum ... antigens of Epstein-Barr virus ... ten 12-well slides, EBNA ...
... DonJoy SpinaLogic is a portable, battery-powered, micro-controlled, ... adjunct electromagnetic treatment to primary lumbar spinal ... This treatment has been shown in ... healing process begin working. Clinical studies have ...
Medicine Products: