Navigation Links
Purines fend off surgery-related damage
Date:12/18/2012

Anesthesia is quite safe these days. But sometimes putting a patient under to fix one problem, such as heart damage, can harm a different organ, such as a kidney.

Now a group of researchers led by Holger Eltzschig, MD, PhD, a professor of anesthesiology at the University Colorado School of Medicine, has found a group of molecules that fend off damage during anesthesia.

"This is a promising discovery," says Eltzschig, who practices at University of Colorado Hospital. "It suggests a new way to promote healing."

In an article published Dec. 12 in the New England Journal of Medicine, Eltzschig and colleagues at Harvard Medical School and Northeastern University report hopeful findings about a group of molecules called purines. Purines are basic molecular building blocks in the body they help produce DNA and RNA and they assist with short-term storage of energy. One variety of purine is called adenosine.

The researchers determined that generating adenosine outside of cells can help protect organs from damage. And they saw that activating adenosine receptors on the lungs, the intestine, or the heart can help protect these organs.

Eltzschig and his fellow researchers looked at adenosine and related chemical processes in cancer, lung injury, bowel inflammation and platelet function, among others.

For patients who might face surgery with anesthesia, the findings are good news.

"Increasing developments in this arena will open up several new avenues for the treatment," the article says.


'/>"/>
Contact: Dan Meyers
dan.meyers@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Page: 1

Related medicine news :

1. d'Oliveira & Associates Help New Bedford Woman Receive $95,000 in Damages for Dog Bite Injury Case #:NB-11736
2. Sleep Apnea Tied to More Brain Damage in Women Than Men
3. Airport Security X-Rays May Damage Diabetes Devices
4. Umbilical cord cells outperform bone marrow cells in repairing damaged hearts
5. Can Playing Soccer Lead to Brain Damage?
6. Two Years On, Stem Cells Still Healing Damaged Hearts
7. A protein’s role in helping cells repair DNA damage
8. Sandy Leaves Massive Blackouts, Flood Damage in Her Wake
9. OHSU researchers discover potential way to repair brain damage in multiple sclerosis
10. Halloween Warning: Decorative Contact Lenses May Damage Your Eyes
11. Experts warn that e-cigarettes can damage the lungs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... For additional information contact Phyllis ... Pioneering book "Better with Age: The Ultimate Guide to Brain Training" by award-winning author ... memory. The book’s publication date is March 16, 2016. A free review copy ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... digital self-scheduling readily available to physicians. The integration will enable Allscripts users ... select appointments via Everseat’s free mobile app. , The partnership gives Everseat substantial ...
(Date:2/10/2016)... CA (PRWEB) , ... February 10, 2016 , ... Workrite ... and most versatile series of monitor mounts ever. , “Our goal was to ... and easy to install system that we have ever created.” said Darren Hulsey, Product ...
(Date:2/10/2016)... ... ... Anxiety of older Americans over steep cost increases of prescription drugs is at ... to The Senior Citizens League (TSCL). Since last fall, TSCL has ... costs. “The implications are chilling, particularly for people with chronic health problems,” says ...
(Date:2/10/2016)... ... February 09, 2016 , ... Ross A. Clevens, MD, ... to welcome a new addition to their growing practice. Beginning this month, Teresa ... nurse practitioner performing cosmetic procedures including injectables, fillers and laser treatments. ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... , Feb. 10, 2016  CVS Health (NYSE: ... people living in Santa Clara County, CA ... B on the Santa Clara University campus. CVS Pharmacy ... to protect patients against the disease. Students at Santa ... to get vaccinated. In addition, anyone who has had ...
(Date:2/10/2016)... , Feb. 10, 2016  Oxis International Inc. (OTC/QB: ... OXS-1550, was described as a "clinical trial triumph" after ... went into complete cancer remission. Daniel ... Minnesota Masonic Cancer Center. --> Daniel ... Minnesota Masonic Cancer Center. --> An ...
(Date:2/10/2016)... 2016  LexisNexis® Risk Solutions, a leading provider ... launch of LexisNexis Provider Performance Monitor , ... and optimize the quality and efficiency of provider ... scores. By measuring provider performance through Provider Performance ... better outcomes, improve the patient experience and reduce ...
Breaking Medicine Technology: