Navigation Links
Purdue researchers create prostate cancer 'homing device' for drug delivery
Date:7/6/2009

WEST LAFAYETTE, Ind. - A new prostate cancer "homing device" could improve detection and allow for the first targeted treatment of the disease.

A team of Purdue University researchers has synthesized a molecule that finds and penetrates prostate cancer cells and has created imaging agents and therapeutic drugs that can link to the molecule and be carried with it as cargo.

A radioimaging application used for body scans is expected to enter clinical trials this fall, and an optical imaging application used to measure prostate cancer cells in blood samples is already in clinical trials.

Philip Low, the Ralph C. Corley Distinguished Professor of Biochemistry who led the team, said a targeted treatment could be much more effective in treating cancer and would greatly reduce the harmful side effects associated with current treatments.

"Currently none of the drugs available to treat prostate cancer are targeted, which means they go everywhere in the body as opposed to only the tumor, and so are quite toxic for the patient," said Low, who is a member of the Purdue Cancer Center. "By being able to target only the cancer cells, we could eliminate toxic side effects of treatments. In addition, the ability to target only the cancer cells can greatly improve imaging of the cancer to diagnose the disease, determine if it has spread or is responding to treatment."

Prostate cancer is the most common cancer, other than skin cancers, and is the second leading cause of cancer death in American men, according to the American Cancer Society. It is estimated that about 192,280 new cases will be diagnosed and 27,360 men will die of prostate cancer in the United States this year.

The molecule Low's team created attaches to prostate-specific membrane antigen, or PSMA, a protein that is found on the membrane of more than 90 percent of all prostate cancers. It also is found on the blood vessels of most solid tumors and could provide
'/>"/>

Contact: Elizabeth K. Gardner
ekgardner@purdue.edu
765-494-2081
Purdue University
Source:Eurekalert  

0

GOOD

Page: 1 2 3 4

Related medicine news :

1. KV Pharmaceutical Company, Purdue Pharma L.P. Settle OxyContin(R) Dispute
2. Purdue study projects weakened monsoon season in South Asia
3. Purdue Pharma L.P. Announces a Global Strategic Alliance With Infinity Pharmaceuticals to Advance Discovery and Development Programs in Oncology and Neuropathic Pain
4. NIH grant to strengthen IU and Purdue program to educate physician-scientists
5. Purdue lab works to improve conditions at indoor swimming pools
6. Purdue Pharma Selects Systech to Provide Sustainable Infrastructure for Serialization
7. Purdue researchers develop technology to detect cancer by scanning surface veins
8. Moles and melanoma -- researchers find genetic links to skin cancer
9. Australian researchers identify genes that cause melanoma
10. Researchers find possible environmental causes for Alzheimers, diabetes
11. IU researchers find vibrator use to be common, linked to sexual health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Purdue researchers create prostate cancer 'homing device' for drug delivery
(Date:5/25/2013)... On May 20, 2013 the Sydney Morning Herald ... or plan for their eventual demise, but it is an ... Must-Do List to help people properly arrange for their last ... fact sheet.” , While not a formal document, this document ... It may include a summary of assets, debts, obtained ...
(Date:5/25/2013)... 2013 The latest report from ... bowel syndrome (IBS) to bloating, constipation, diarrhea and ... long-lasting, embarrassing, frustrating and difficult health issues to ... health have provided a cure for these ... contributing to digestive health issues, a healthy diet ...
(Date:5/25/2013)... On May 25, Voices Against Brain ... advocacy, comments on a new study by the Max ... atmospheric plasma into brain cancer treatment may help when ... Science Daily article, physicists from the Max ... demonstrated the “synergistic effect of cold atmospheric plasma -- ...
(Date:5/25/2013)... 25, 2013 Many orthodontists have thought ... where exactly that cloud is. Most people would ... with to provide their cloud service and support would ... the service they're selling, they'd be wrong. Cloud ... (a secure, redundant facility that houses servers and related ...
(Date:5/25/2013)... According to world-renowned scholars, Queen Cleopatra VII was ... ever lived. Cleopatra’s legendary beauty moved nations and her ... men in her time. Cleopatra was also a scientist ... glowing and fresh, from her legendary milk baths to ... cyprus grass. , Cleopatra was said to possess the ...
Breaking Medicine News(10 mins):Health News:FuneralFinancials.com Releases Last Wishes Must-Do List 2Health News:Natural Foods For Digestive Health Report and Video Published by BetterDigestion.org 2Health News:Voices Against Brain Cancer Comments on Study that Shows Cold Plasma’s Success Against Brain Cancer Cells 2Health News:Cirrus Ortho Launches Cloud Computing for Orthodontic Industry That is Unlike Any Other 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 3
... cancer treatments using their knowledge about an obesity drug, orlistat ... in the laboratory . ,The drug binds and ... the protein's function and causes cell death. ,The ... Kridel and W. Todd Lowther at Wake Forest University School ...
... serve to repress an alcoholic's desire for drink, according ... of California-San Francisco . ,Varenicline, manufactured by ... the United States and Europe in 2006, has been ... reward system for addictive substances. ,The research ...
... that a large number of Internet searches are health ... the healthcare sector . This, claims Cambridge UK based ... and medical device manufacturers. According to a series of ... having to come to terms with informed patients who ...
... into a skin-care product that would wipe away wrinkles and ... ,The government's team of camel researchers, which has already pioneered ... found cosmetic properties in the hardy mammal's milk. ... a hospital's skin department to study it on 20 people ...
... or kill tumors in the pancreas of mice, US researchers ... of the deadliest human cancers ,The mutant gene ... kill themselves, researchers from The University of Texas MD Anderson ... more lethal mutant, called BikDD, which spares healthy tissue. ...
...
Cached Medicine News:Health News:Battle Between Google and Microsoft Could Trigger Revolution in Healthcare 2Health News:Mutated Gene Zaps Pancreas Cancer in Mice 2
(Date:5/23/2013)... 23, 2013 Neurocrine Biosciences, Inc. (Nasdaq: ... , President and Chief Executive Officer of Neurocrine Biosciences, will ... dbAccess Health Care Conference in Boston.   The ... a.m. Eastern Time / 8:20 a.m. Pacific Time.  The presentation ... website at http://www.neurocrine.com . If you ...
(Date:5/23/2013)... 23, 2013  Haemonetics Corporation (NYSE: HAE ) ... & EVP-Business Development, will present at The Deutsche Bank 38 ... Boston, MA on May 29, 2013 at 1:30pm ... The public may access Mr. Lindop,s presentation live ... Haemonetics Haemonetics (NYSE: HAE ) is ...
(Date:5/23/2013)... WASHINGTON , May 23, 2013 Hearing health ... active, feel younger, and remain socially and professionally engaged, he ... is the overriding message that the Better Hearing Institute ... support of National Men,s Health Week , which leads ... Health Week runs from June 10 through June 16. ...
Breaking Medicine Technology:Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4
... Hospital (MGH) Cancer Center has purchased four radiation therapy treatment ... and one Elekta Synergy® S. The order, which includes ... facility to offer patients a complete cancer treatment solution from ... systems position MGH to take advantage of Volumetric ...
... 2 The Asthma and Allergy Foundation of America (AAFA) ... annual research project ranks the fall,s 100 most challenging cities ... this year are: McAllen, TX (1); Wichita, KS (2); Louisville, ... In addition, according to a recent AAFA survey, fall ...
Cached Medicine Technology:Massachusetts General Hospital Selects Elekta As New Vendor for Complete Cancer Treatment Solution 2New Fall Allergy Capitals(TM) Reveal the Most Challenging Cities for Allergy Sufferers 2New Fall Allergy Capitals(TM) Reveal the Most Challenging Cities for Allergy Sufferers 3New Fall Allergy Capitals(TM) Reveal the Most Challenging Cities for Allergy Sufferers 4New Fall Allergy Capitals(TM) Reveal the Most Challenging Cities for Allergy Sufferers 5New Fall Allergy Capitals(TM) Reveal the Most Challenging Cities for Allergy Sufferers 6
... the parafollicular C-cells of the thyroid gland ... major action of calcitonin is to lower ... resulting in decreased mobilization of calcium from ... in conditions associated with high levels of ...
Calcitonin RIA Kit...
Validated by decades of research and clinical experience, HFA is the accepted standard of care in glaucoma diagnosis and management. With HFA you can feel confident you're providing the best possible...
... been a standard requirement for ... during laser procedures, however, many ... that smoke plume generated from ... as smoke plume generated from ...
Medicine Products: