Navigation Links
Pulse pressure elevation could presage cerebrovascular disease in Alzheimer's patients
Date:4/6/2012

Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer's disease (AD). Their study has been published in the early online edition of Journal of Alzheimer's Disease in advance of the June 5 print publication.

The findings may have treatment implications, since some antihypertensive medications specifically address the pulsatile component of blood pressure. Pulse pressure (PP) the difference between systolic and diastolic pressure is one measure of the pulsatile component of blood pressure. PP increases substantially with age, partially due to hardening of the arteries.

Hypertension is a common risk factor for AD, but the use of antihypertensive medications to prevent dementia has had mixed results. Most studies examining the effects of blood pressure on the risk of AD have focused on standard measures of blood pressure, the systole and diastole readings. However, scientists theorized that PP elevation may impair the clearance of beta amyloid a hallmark of AD from the brain. Other studies have suggested that PP elevation may contribute to AD risk indirectly by increasing the risk of CVD.

The researchers, led by Mark W. Bondi, PhD, of VA San Diego Healthcare System and UC San Diego Department of Psychiatry, looked at 65 patients who later met the criteria for AD at autopsy. These patients were examined before death for relationships among blood pressure and neuropathologic markers. More than half of them were found, at autopsy, to have CVD.

"The association between PP and CVD was independent of dementia severity and the presence of other vascular risk factors," said Bondi. "Interestingly, standard measures of blood pressure were not significantly associated with the presence of CVD."

The study suggests several conclusions: tha
'/>"/>

Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert

Page: 1 2

Related medicine news :

1. SportsDirect Inc. and Enetpulse Form Global Sports Information Alliance
2. Electromagnetic pulses provide pain relief for osteoarthritis
3. Electromagnetic Pulses May Stem Arthritic Knee Pain
4. Six Degrees Launches ePulse - an Online Buzz Monitoring Tool
5. Queens University researchers locate impulse control center in brain
6. Membrane molecule keeps nerve impulses hopping
7. BMC doctor recognized by World Health Organization for pulse oximetry training video
8. Mayo Clinic CPR efforts successful on man with no pulse for 96 minutes
9. Pulse oximetry: A viable screening tool for infants with suspected congenital heart disease
10. Infants Faces Trigger Caregiving Impulse in Adults Brains
11. Electrical pulse treatment gives pancreatic cancer patients new hope
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/5/2015)... On March 2, 2015, NBC News ... the Rise, Plastic Surgeons Say,” that comments on the ... Aesthetic Plastic Surgery and the American Society ... year-over-year doubling of surgical butt augmentations performed in 2014. ... article, this increase can be attributed to the social ...
(Date:3/5/2015)... HMP Communications Holdings , LLC ... announced today its acquisition of the Amputation ... conference designed for health care providers dedicated to ... due to vascular disorders. The 5-year-old meeting ... and CME activities across therapeutic fields such as ...
(Date:3/5/2015)... Venice, FL (PRWEB) March 05, 2015 ... their 15th annual listing of “Pros to Know” in ... announce that two members of MEBC’s leadership team were ... Rhodes were nominated and received this award due to ... use of innovative methods for meeting and resolving client ...
(Date:3/5/2015)... Leading nutritional supplement provider Metabolic Nutrition ... and Arnold Fitness EXPO in Columbus, Ohio ... a display booth featuring free samples of its superior ... class-leading fat burner Synedrex. The company will also be ... its top-of-the-line supplements and miniature action figures of its ...
(Date:3/5/2015)... (PRWEB) March 05, 2015 Think it’s tough ... even tougher to get them to brush their teeth. That’s ... parents released today by Delta Dental(1) in conjunction with National ... (45 percent) say getting kids to brush their teeth is ... to do. That’s slightly higher than getting children to eat ...
Breaking Medicine News(10 mins):Health News:The Kim Kardashian and Jennifer Lopez Effect: Butt Augmentations Double from 2013 to 2014 2Health News:HMP Holdings Acquires The Amputation Prevention Symposium (AMP) 2Health News:HMP Holdings Acquires The Amputation Prevention Symposium (AMP) 3Health News:MEBC Leaders Awarded Supply Demand Chain Executive Pros to Know Title For 2015 2Health News:Metabolic Nutrition Exhibiting at 2015 Arnold Sports Festival and Fitness EXPO This Week 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 3
... environment and energy related products and services, has ... technology effectively suppresses avian influenza viruses. // ... national university in south western Japan,Sanyo’s proprietary electrolysed ... Mist’ system was shown highly effective in suppressing ...
... biotech, the company that is known for being the sole ... known, about its intention to go public//. The company is ... per the papers filed with the Securities and Exchange Commission. ... and debates have been raging about what this science can ...
... in the British Journal of Clinical Pharmacology states that 10% ... providing morning-after pill at local pharmacies //as they have the ... Kent Primary Care Trust and the University of Bradford looked ... the medication from family planning clinics and community pharmacies. ...
... a mouse model by the Oregon Health & Science University ... of the often devastating// head and neck squamous cell cancers. ... Ph.D., and his colleagues. The results of their research breakthrough ... & Development. ,‘This is the first animal model ...
... by the researchers of Obstetricians and Gynecologists at the new ... can be tiresome and complicated. They say that this could ... of obese pregnant women it takes a longer time to ... at the annual meeting of the American College of Obstetricians ...
... will be made available to every Canadian who gets ill ... to combat a potential pandemic. ,The Minister ... A strategy is now in place to make sure everyone ... been initiated to equip the provinces to combat any public ...
Cached Medicine News:Health News:Sanyo’s Electrolysed Water Technology Effective In Suppressing Bird Fl 2Health News:Morning-After Pill At The Local Pharmacy Could Prevent Unwanted Pregnancies 2Health News:Morning-After Pill At The Local Pharmacy Could Prevent Unwanted Pregnancies 3Health News:Mouse Model Beneficial to Study of Head and Neck Cancer 2
(Date:3/5/2015)... , March 5, 2015 CANTEL MEDICAL CORP. (NYSE: ... second quarter ended January 31, 2015 on Thursday, March 12 ... discuss the results at 11:00 AM ET. ... 5 to 10 minutes before the beginning of the call. ... the call will be available from Thursday, March 12, 2015 ...
(Date:3/5/2015)...   ndd Medical Technologies , a leader in ... ultrasound technology, announced that its EasyOne Pro® was used ... Antonio Pulmonary Fibrosis Support Group. The clinic targeted patients ... as well as those suspected of having ILD or ... 12 square inches, EasyOne Pro provides accurate respiratory test ...
(Date:3/5/2015)... 5, 2015   AMC Health , the ... for improving the effectiveness and efficiency of healthcare ... Anazagasty and Jared Wilstead have ... President, Strategic Client Development, and Wilstead will serve ... AMC Health,s commitment to accelerating the adoption of ...
Breaking Medicine Technology:Cantel Medical Corp. To Hold Conference Call To Discuss Results For Its Second Quarter Ended January 31, 2015 2ndd Medical Technologies' Mobile Pulmonary Function Testing Helps Combat Pulmonary Fibrosis 2ndd Medical Technologies' Mobile Pulmonary Function Testing Helps Combat Pulmonary Fibrosis 3AMC Health Bolsters Sales Team with Robert Anazagasty and Jared Wilstead 2AMC Health Bolsters Sales Team with Robert Anazagasty and Jared Wilstead 3
... 17, 2012 Morgan honored with The ... The National Council for Prescription Drug Programs ... throughout the pharmacy services industry, awarded Kay Morgan, Senior Vice ... for Elsevier / Gold Standard , with its highest ...
... N.C., May 17, 2012  The performance of high intensity ... invasive treatment of prostate cancer is the focus of ... Annual Meeting of the American Urological Association (AUA), in ... HIFU), a world leader in minimally invasive HIFU technologies, ...
Cached Medicine Technology:Elsevier / Gold Standard's Kay Morgan Awarded NCPCP Highest Honor 2Elsevier / Gold Standard's Kay Morgan Awarded NCPCP Highest Honor 3US HIFU to Showcase High Intensity Focused Ultrasound for the Treatment of Prostate Cancer at AUA 2US HIFU to Showcase High Intensity Focused Ultrasound for the Treatment of Prostate Cancer at AUA 3
The Oculus easyfield is an exciting new compact perimeter to do automatic static perimetry up to 30 degrees eccentricity. It has been designed for the combined use as a visual field screener and peri...
Automatic tangent screen with plane type central field tester. Static, quantitative perimetry....
Focus Dailies Toric are the first daily disposable lens for astigmatism...
Frequency 55 Toric XR is a great option for those with high levels of astigmatism...
Medicine Products: