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Published Study Shows More Patients See Improvement in Overactive Bladder Symptoms With Urgent(R) PC Device Compared to Those Using a Drug
Date:9/3/2009

female with an average age of 58 years, and an average history of OAB duration of more than 9 years.

"PTNS may be considered a clinically significant alternative to pharmacologic therapy for the treatment of OAB with statistically significant improvements in patient self-assessments compared to drugs, and comparable objective effectiveness," said Dr. Kenneth M. Peters, the primary author, and Chairman of the Department of Urology at Beaumont Hospital in Royal Oak, Michigan. "PTNS represents an important addition to our therapeutic armamentarium."

Dr. Peters led the 12-week OrBIT (Overactive Bladder Innovative Therapy) multi-center trial, on which the article "Randomized Trial of Percutaneous Tibial Nerve Stimulation Versus Extended-Release Tolterodine: Results From the Overactive Bladder Innovative Therapy Trial" is based.

The results confirm that Urgent PC's PTNS reduces the incidence of voiding episodes at a rate comparable to extended-release tolterodine, known by the trade name Detrol(R) LA (Pfizer), the leading pharmaceutical therapy for OAB, and that patients report a statistically significant decrease in their overall OAB symptoms compared to patients on extended-release tolterodine.

The study of 100 patients was conducted in 11 U.S. centers. These patients were randomized to either PTNS treatment with Urgent PC, or to extended-release tolterodine. All patients in the study were diagnosed with urinary frequency at eight or more voids per day. Patients randomized into the PTNS treatment were treated weekly for 12 consecutive weeks, while patients randomized into the pharmacologic therapy were given a 90-day prescription of 4 mg daily. All patients completed voiding and bladder control diaries and questionnaires at baseline and after completion of 12 weeks of treatment.


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SOURCE Uroplasty, Inc.
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