Navigation Links
'Publication Bias' Casts Doubt on Value of Antidepressants for Autism
Date:4/23/2012

By Jenifer Goodwin
HealthDay Reporter

MONDAY, April 23 (HealthDay News) -- Studies that show a type of antidepressant eases autism symptoms are more likely to get published in medical journals than studies concluding the drugs don't improve common behaviors such as rocking and hand-flapping, new research says.

That "publication bias" may mean that physicians believe the medications -- known as selective serotonin reuptake inhibitors (SSRIs) -- are more effective than they really are for children with these behaviors. Indeed, when researchers combined the data from published studies and those that never made it into print, the new analysis showed that SSRIs don't help repetitive behaviors much at all.

"At least from what we have right now, we need more information to determine if SSRIs are useful in treating repetitive behavior," said study author Melisa Carrasco, of the neuroscience graduate program at the University of Michigan in Ann Arbor. "I don't think we're trying to say they should not be used at all in autism. There is some compelling evidence toward their use in treating anxiety disorders in autism."

The study, in the May print issue of Pediatrics, appears online April 23.

The study also calls into question the effectiveness of current methods used to evaluate drugs, particularly pediatric drugs, in the United States. One expert said the findings have implications for countless other drug trials for other conditions.

It's long been recognized that drug trials that show the drug is effective are more likely to be published in peer-reviewed journals, where the results are widely read and disseminated to doctors, said Dr. Scott Denne, a professor of pediatrics at Indiana University School of Medicine, who wrote an accompanying editorial.

"Positive studies are exciting and potentially groundbreaking. Negative studies are not particularly exciting and at least in the estimation of
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. Video publication goes viral
2. Oxford University Press acquires 2 journals from Preston Publications
3. Charles to receive GSAs 2011 Richard Kalish Innovative Publication Award
4. IASLC welcomes publication of CT screening results from National Lung Screening Trial
5. ACP Publications take home awards for publishing excellence
6. Elsevier Health Middle East announces publication of first bilingual medical title
7. PSA screening declines following publication of large trials, guidelines
8. Publication of World Health Report 2000 an act of remarkable courage, says school expert
9. Trainee publication highlights success of US-China agricultural injury research training project
10. The International Association of Anesthesiologists Places its Top Doctors in the Renowned Medical Publication, The Leading Physicians of the World.
11. HealthLeaders Magazine Named Publication of the Year – ASHPE's Most Prestigious Award
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Publication Bias' Casts Doubt on Value of Antidepressants for Autism
(Date:5/19/2013)... Passages Malibu, the leading non-12 step, ... this week the launch of a “Sobriety, Health, and ... channels. “We are always looking for new ways ... get feedback regarding sobriety, what’s working for people, and ... the Passages Addiction Treatment Centers located in ...
(Date:5/19/2013)... May 19, 2013 The AMTC team will ... the Columbus Georgia Convention & Trade Center on June 1st. ... attend. AMTC auditions are free of charge. , Actors, Models ... for hundreds of successful artists and grads like Caitlin Kinney ... European Tombolini , Chris Young - on his Liquid Neon ...
(Date:5/19/2013)... The legal team at Pulaski & Middleman, ... effort to connect women and families coping with the ... Yasmin & Ocella with the legal representation they need. ... notorious birth control drugs as well as news and ... Yasmin & Ocella were very popular birth control medications ...
(Date:5/18/2013)... COOLA, British Columbia (PRWEB) May 19, 2013 ... to Cooking” (published by iUniverse) , author Janet Hall Svisdahl’s ... delectable world recipes sure to make even the pickiest ... living peacefully, pleasurably and prayerfully,” she explains. , Found ... Spirit” are a wide range of delicious recipes, from fast ...
(Date:5/18/2013)... Each year, the American Gastroenterological Association (AGA) ... achievements in gastroenterology through its esteemed recognition awards. ... talented individuals who work tirelessly to advance the ... pleased to announce the 2013 recognition award honorees ... their tremendous contributions to our field," said Loren ...
Breaking Medicine News(10 mins):Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 2Health News:Passages Malibu Announces its Sobriety, Health, and Wellness Social Media Survey 3Health News:Actors, Models and Talent for Christ Hosting Auditions in Columbus, GA June 1st in Search of Local Talent 2Health News:Yazsideeffects.com Connects Yaz Side Effects Sufferers With Yaz Side Effects Lawyers 2Health News:Janet Hall Svisdahl Announces Release of ‘Cooking with Spirits for the Spirit’ 2Health News:AGA honors distinguished clinicians, researchers and educators with prestigious recognition awards 2Health News:AGA honors distinguished clinicians, researchers and educators with prestigious recognition awards 3Health News:AGA honors distinguished clinicians, researchers and educators with prestigious recognition awards 4Health News:AGA honors distinguished clinicians, researchers and educators with prestigious recognition awards 5
... in to Boston from India, on April 26, brought over ... the 18th floor of the John Hancock Tower, little did ... ,On May 5 the characteristic symptoms of measles ... measles struck another half-dozen workers at Investors Bank & Trust, ...
... at new prescription- only medicines that were publicly funded between 2000 ... new prescription-only medicines have been listed on the Australian PBS, ... are registered in New Zealand, of which only 20 are ... New Zealand is slower to fund new drugs when compared ...
... the Queensland Department of Primary Industries (DPI) has quarantined ... ,Although the DPI has not yet confirmed what ... could be serious.,The general manager of plant biosecurity, Chris ... trace-back and trace-forward process and would also begin surveillance ...
... has provided $7 million towards development of some of ... //. ,According to the incoming president of ... beds and acute care beds would help to provide ... opinions differ, with Dr. Margaret MacDiarmid hoping that new ...
... According to the doctors at Kozhikode Medical College Hospital, Kerala ... //. ,The man named Akkooppoyil Achuthan aged 65 ... six Kg tumor. ,Then he was discharged but ... an X-ray another doctor found the scissors in the stomach. ...
... of the gene responsible for Type 2 diabetes scientists have ... //. ,The PSARL gene associated with the Type ... in Washington tomorrow. ,Diabetes, now considered as an ... about $3 billion annually. ,Diabetes has long been ...
Cached Medicine News:Health News:Global Threat of Measles Outbreak 2
(Date:5/16/2013)... 2013  Nektar Therapeutics, (Nasdaq: NKTR ) President ... , is scheduled to present at the upcoming 2013 UBS ... at the Sheraton New York Hotel on Tuesday, May 21, ... will be accessible via a Webcast through a link posted ... website: http://www.nektar.com . This Webcast will be available for ...
(Date:5/16/2013)... Mass. , May 16, 2013  Alere Inc. (NYSE: ... to take charge of their health at home through the ... cash dividend of $3.00 per share on its Series B ... on July 15, 2013 to holders of record of Series ... 2013.  Such payment will cover the amount of ...
(Date:5/16/2013)... , May 16, 2013 OrthoView ... the U.S. to access the widely-used OrthoView digital templating ... and Internet connection to get started. OrthoView, ... for over 10 years, is dedicated to enabling orthopaedic ... digital x-ray images, when printed film is unavailable. Over ...
Breaking Medicine Technology:Nektar Therapeutics' President and CEO, Howard W. Robin, To Present at the 2013 UBS Global Healthcare Conference in New York City 2OrthoView Announces the U.S. Launch of a New, Subscription-based, Digital Planning and Templating Solution for Individual Orthopaedic Surgeons 2
... Nile Therapeutics,Inc. (Nasdaq: NLTX ), today announced ... placebo-controlled clinical study of CD-NP, a novel,chimeric natriuretic ... heart failure., The primary objective of the ... physiologic parameters of intravenous infusions of,CD-NP in patients ...
... Transplant Monitoring Test that Meets International Standards for ... ... The ability of blood,tests to precisely measure very low doses ... difference in assuring long-term,viability and survival, according to research presented ...
Cached Medicine Technology:Nile Therapeutics Announces Dosing in Second Phase Ib Study of CD-NP in Heart Failure Patients 2Nile Therapeutics Announces Dosing in Second Phase Ib Study of CD-NP in Heart Failure Patients 3Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success 2Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success 3
... Stabilizer Plastazote® with plastic anterior ... straps. Chin cradle reduces rotation. ... be interchanged for individualized fitting.,Philadelphia™ ... standard Philadelphia Collar for added ...
Bougie Urethrotomes for slitting the female urethra and for meatus stenosis in males...
Optical Mini Urethrotome for telescope 3.3 mm, 0...
... cystoscope is being used more and more as ... outstanding optical quality and large working/irrigation channel, the ... therapy. The outstanding flexibility of the cystoscope guarantees ... Being simple ...
Medicine Products: