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Psychiatric Meds in Water Supply May Alter Fish Behavior
Date:2/15/2013

FRIDAY, Feb. 15 (HealthDay News) -- Small amounts of mood-altering drugs used to treat psychiatric disorders that are making their way into rivers and streams may be changing the behavior of some fish, a new study suggests.

Researchers in Sweden found exposure to the anti-anxiety drug, Oxazepam, caused fish to become bolder, less social and eat faster.

Reporting in the Feb. 15 issue of Science, the researchers explained that trace amounts of the drug and other medications end up in waterways downstream of wastewater treatment plants, after being excreted by people. The team worries that exposure of wildlife to pharmaceuticals such as Oxazepam could eventually lead to unexpected ecological and evolutionary consequences.

In the study, the researchers gave wild European perch a dose of Oxazepam that was similar to the amounts of the drug found in Sweden's waterways. They found that even trace amounts of the mood-altering medication seemed to alter the behavior and foraging rate of the wild perch.

"Normally, perch are shy and hunt in schools. This is a known strategy for survival and growth. But those who swim in Oxazepam became considerably bolder," lead researcher Tomas Brodin, an ecologist at Umea University, said in a university news release.

He said that perch exposed to Oxazepam became more independent, leaving the safety of schools to forage on their own - potentially exposing themselves to being eaten by other fish.

"In contrast, unexposed fish stayed hidden in their refuge," Brodin said in a news release from Science.

Since the fish also ate their food more quickly, the researchers pointed out, this behavior could change the composition of species in the water. This unbalance, they added, could alter ecological events over time, such as the blooming of algae.

Exposure to Oxazepam also made the fish less social, making them easier prey for potential predators, the research
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