Navigation Links
Psoriasis medication rises hope in the fight against multiple sclerosis
Date:3/7/2011

Fumaric acid salts have been in use against severe psoriasis for a long time. About ten years ago, researchers in Bochum speculated that they may also have a favourable effect on Multiple Sclerosis (MS) as a result of their TH2 polarizing mechanisms. In parallel to phase III studies, research is actively searching for the precise effective mechanisms. This has now been achieved by a neuroimmunological group at Bochum: fumaric acid salts detoxify radicals released during the inflammation process. In this way, they protect nerve and glial cells. Neurologists at the Ruhr University Hospital, St. Josef Hospital, working with Prof. Dr. Ralf Gold report early online in the leading neurology journal BRAIN.

Previous history. inspiration from dermatology

Like Multiple Sclerosis, psoriasis is an auto-immune disease, in which the immune system attack the body's own cells. In MS, the "insulating myelin layer" of the axons is destroyed in this way. About ten years ago, the RUB dermatologist Prof. Peter Altmeyer informed his colleague, the neurologist Prof. Horst Przuntek, that the mixture of fumaric acid salts registered for treatment of psoriasis under the trade name FUMADERM could possibly exert favourable effects in MS as well. In turn, the Swiss manufacturer Fumapharm sponsored a small study in Bochum. Ten patients were examined for a period of 48 weeks (Schimrigk et al European Journal of Neurology 2006, 13: 604�). In Parallel to this, Fumapharm supported basic research which Prof. Gold then performed at his MS Institute in Gttingen (Schilling et al. Clin Exp Immunology 2006; 145: 101-107).

Fumaric acid salts detoxify radicals and protect nerve cells

After that, the scenario moved rapidly: the US pharmaceutical company BiogenIdec with its focus in MS research took over Fumapharm AG and initiated a successful Phase II study (Kappos, Gold, Lancet 2008; 372: 1463󈞴). Parallel to this, the group arou
'/>"/>

Contact: Dr. Ralf Gold
49-023-450-92410
Ruhr-University Bochum
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Project Runways Tim Gunn Returns to Address Psoriasis(TM) and Empower Patients to be Confident in Their Personal Style
2. Psoriasis is More Than Skin Deep
3. Psoriasis Tied to Raised Heart Risk
4. LeAnn Rimes Brings Battle With Psoriasis to Center Stage
5. Acne, Psoriasis Meds Dont Raise Fracture Risk
6. Insurance Woes Can Add to Burden of Psoriasis
7. Beer Linked to Psoriasis in Women
8. Kids With Psoriasis Often at Risk of Being Bullied: Survey
9. Psoriasis Linked to Raised Heart Risks
10. Certain pain medications do not appear to be associated with skin cancer risk
11. Study supports alternative anti-seizure medication following acute brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Boston Children’s Museum and From the ... series, introducing young Museum visitors to musicians from ... national platform celebrating the stories, talents, and character ... musicians featured will also be showcased on NPR's ... fortunate to partner with the wonderful musicians of ...
(Date:9/17/2014)... 2014 Why are Asian Americans at higher risk ... prone to develop the disease at lower body weights? ... transition from traditional high-fiber, low-fat Asian diets to current ... of Asian heritage, says George King, M.D., Senior Vice ... and the senior author of the study. , A ...
(Date:9/17/2014)... Leading eco-friendly beauty brand , Lotus Moon, ... vegan and gluten-free Sugar Cane Fruit Mask. Their newest ... skincare testers were looking for. , “My goal ... that provided results, and I think I accomplished it,” ... Mask combines Willow bark (Salix Alba extract), a natural ...
(Date:9/17/2014)... The Delta Dental Community Care Foundation announced ... Oral Health Foundation: America’s ToothFairy (NCOHF) to support oral ... Health Zone Program® in California. , The Orange County ... of local constituent groups and stakeholders in a comprehensive ... and its devastating effects on local families. The support ...
(Date:9/17/2014)... Managing diabetes, quitting smoking, controlling high blood pressure, exercising ... for dementia -- even late in life, according to ... commissioned by Alzheimer,s Disease International, revealed that diabetes can ... study noted that obesity and an inactive lifestyle are ... blood pressure. The researchers suggested that dementia ...
Breaking Medicine News(10 mins):Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 2Health News:Boston Children's Museum Partners with From the Top to Offer Monthly Concert Series 3Health News:In Joslin trial, Asian Americans lower insulin resistance on traditional diet 2Health News:In Joslin trial, Asian Americans lower insulin resistance on traditional diet 3Health News:EcoBeauty Brand Lotus Moon Unveils New Gluten-Free Sugar Cane Fruit Mask 2Health News:Delta Dental Community Care Foundation Donation to America's ToothFairy Helps Deliver Critical Services 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 3
... scientists have developed a hormone-free contraceptive pill for men they ... tablet, developed by researched at King's College London, can be ... being able to impregnate a woman. However, his fertility would ... edition of Daily Mail. ,Contraceptive pills available in ...
... Jai Prakash Narayan Apex Trauma Center (JPNATC), which was conceived ... patients of road accidents. ,The All India ... sq meters, seven-storey hospital with 200 beds, including 16 ICU ... dry run on Monday by shifting 55 'not so critical ...
... unearthed clues,from studies on dragonflies, that may help in ... revealed that when dragonflies are infected with certain parasites ... similar to the Type -2 diabetes seen in humans. ... studies may hold the key to understanding the underlying ...
... the Department of Molecular, Cellular and Developmental Biology (MCDB) ... awarded// the prestigious 2006 E. B. Wilson Medal, ... scientific research in cell biology. ,The medal ... assembly, maintenance and function of fine, hair-like cell organelles, ...
... brain protein known to underlie a form of Parkinson's disease ... branching of neurons//, researchers have found. They have pinpointed the ... gene called LRRK2 and how it affects neurons, ultimately leading ... to the pathology of PD, and loss of connections among ...
... in 2002 to work in the National Health Service but was ... incurable brain disease, will now be// able to return to India ... ,Kaushik Chatterjee, a doctor from Kolkata, came to Britain in ... was appointed senior house officer in elderly care at Sunderland Royal ...
Cached Medicine News:Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 2Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 3Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 4Health News:Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum 5Health News:Parkinson's Mutation Stunts Neurons 2Health News:Ailing Indian doctor in Britain to return to Kolkata 2
(Date:9/17/2014)...  Dr. Stephen Loyd , a recovering substance ... National Recovery Month, stars in a new television ad ... advocates were also joined by a Los ... her fiancée because of a preventable error in surgery ... of crack cocaine abuse. Proposition 46 would identify doctors ...
(Date:9/17/2014)... , Sept. 17, 2014 /PRNewswire-iReach/ -- ChemImage ... paper discussing improvements in the development of ... for both normal and diseased tissue that ... simplifies surgical procedures, lowers surgical costs and ... procedures. The clinical and ...
(Date:9/17/2014)... Calif. , Sept. 17, 2014 ... Prostate Vanguard, an awareness campaign to educate men about ... needle biopsies of the prostate. Annually, a million ... gland through the rectum. Multi-parametric MRI (MP-MRI) of the ... prostate cancer (CSPC). Men need to be fully ...
Breaking Medicine Technology:Doctor Recovering From 100-Pill-A-Day Addiction Stars In New Ad Supporting Prop 46; Appears At White House for National Recovery Month, Says Consumer Watchdog Campaign 2Doctor Recovering From 100-Pill-A-Day Addiction Stars In New Ad Supporting Prop 46; Appears At White House for National Recovery Month, Says Consumer Watchdog Campaign 3Patient Outcomes Improve When Molecular Chemical Imaging Technology Is Used to Aid Robotic Surgical Procedures, According to New White Paper 2Prostate Cancer Awareness Month - Stop Random Biopsies 2Prostate Cancer Awareness Month - Stop Random Biopsies 3
... 2 MedAvante, Inc., the leader in centralized evaluation of central nervous ... Service for trials assessing Alzheimer,s Disease. Its CQC Services are already in use ... in the United States , Europe , Asia , ... , , ...
... HARBIN, China , June 2 /PRNewswire-Asia-FirstCall/ ... a,developer, manufacturer and distributor of botanical products,bio-pharmaceuticals and traditional Chinese ... a conference call at 9:00 a.m. Eastern Time ... for the second quarter of its,fiscal year 2010, ended ...
Cached Medicine Technology:MedAvante Launches Service to Boost Reliability of Assessments to Reduce Risk of Failed Alzheimer's Disease Trials 2MedAvante Launches Service to Boost Reliability of Assessments to Reduce Risk of Failed Alzheimer's Disease Trials 3Renhuang Schedules Conference Call to Discuss FY 2010 Second Quarter Results 2Renhuang Schedules Conference Call to Discuss FY 2010 Second Quarter Results 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: